Home LiteratureArticle Details
PMID: 2509435 Published · ppublish English Comparative Study Journal Article Research Support, Non-U.S. Gov't

Structural similarity among Escherichia coli FtsW and RodA proteins and Bacillus subtilis SpoVE protein, which function in cell division, cell elongation, and spore formation, respectively.

Journal of bacteriology ·Vol. 171 ·No. 11 ·1989-11-00 ·Pages 6375-8

Ikeda M, Sato T, Wachi M, Jung HK, Ishino F, Kobayashi Y, Matsuhashi M

Abstract

The Escherichia coli cell division gene ftsW (2 min) was cloned and sequenced. It encodes a hydrophobic protein(s) with 414 and/or 384 amino acid residues. The deduced amino acid sequence and the hydropathy profile of the protein showed high homology with those of the E. coli RodA protein functioning in determination of the cell shape and the Bacillus subtilis SpoVE protein functioning in spore formation. Probably similar functional membrane proteins are involved in these three cell cycle process.

MeSH Terms
Amino Acid Sequence Bacillus subtilis/cytology,genetics,physiology Bacterial Proteins/genetics Base Sequence Cell Division Cloning, Molecular Escherichia coli/cytology,genetics,physiology Escherichia coli Proteins Genes, Bacterial Genetic Complementation Test Membrane Proteins Molecular Sequence Data Multigene Family Protein Conformation Restriction Mapping Sequence Homology, Nucleic Acid Sigma Factor Spores, Bacterial/physiology Transcription Factors
Chemicals
Bacterial Proteins Escherichia coli Proteins Membrane Proteins Sigma Factor Transcription Factors spoIIR protein, Bacillus subtilis spore-specific proteins, Bacillus mrdB protein, E coli FtsW protein, Bacteria
Authors & Affiliations
7 authors, click to expand affiliations / ORCID
Ikeda M
Institute of Applied Microbiology, University of Tokyo, Japan.
Sato T
Wachi M
Jung H K
Ishino F
Kobayashi Y
Matsuhashi M
References (19)
19 references, click to expand
  1. Identification of new genes in a cell envelope-cell division gene cluster of Escherichia coli: cell envelope gene murG.
    J Bacteriol. 1980 Oct;144(1):438-40 PMID: 6998962
  2. Genetic aspects of bacterial endospore formation.
    Bacteriol Rev. 1976 Dec;40(4):908-62 PMID: 12736
  3. Peptidoglycan synthetic enzyme activities of highly purified penicillin-binding protein 3 in Escherichia coli: a septum-forming reaction sequence.
    Biochem Biophys Res Commun. 1981 Aug 14;101(3):905-11 PMID: 7030331
  4. Identification of the rodA gene product of Escherichia coli.
    J Bacteriol. 1983 Aug;155(2):854-9 PMID: 6348029
  5. Rapid and sensitive protein similarity searches.
    Science. 1985 Mar 22;227(4693):1435-41 PMID: 2983426
  6. Structure and expression of the cell division genes ftsQ, ftsA and ftsZ.
    J Mol Biol. 1985 Aug 5;184(3):399-412 PMID: 2995680
  7. Peptidoglycan synthetic activities in membranes of Escherichia coli caused by overproduction of penicillin-binding protein 2 and rodA protein.
    J Biol Chem. 1986 May 25;261(15):7024-31 PMID: 3009484
  8. Nucleotide sequence of the pbpA gene and characteristics of the deduced amino acid sequence of penicillin-binding protein 2 of Escherichia coli K12.
    Eur J Biochem. 1986 Oct 15;160(2):231-8 PMID: 3533535
  9. Nucleotide sequence of the Bacillus subtilis developmental gene spoVE.
    J Gen Microbiol. 1986 Jul;132(7):1883-90 PMID: 3098901
  10. Production of single-stranded plasmid DNA.
    Methods Enzymol. 1987;153:3-11 PMID: 3323803
  11. Determinations of the DNA sequence of the mreB gene and of the gene products of the mre region that function in formation of the rod shape of Escherichia coli cells.
    J Bacteriol. 1988 Oct;170(10):4619-24 PMID: 3049542
  12. Cloning and characterization of Bacillus subtilis homologs of Escherichia coli cell division genes ftsZ and ftsA.
    J Bacteriol. 1988 Oct;170(10):4855-64 PMID: 3139638
  13. Nucleotide sequence of the rodA gene, responsible for the rod shape of Escherichia coli: rodA and the pbpA gene, encoding penicillin-binding protein 2, constitute the rodA operon.
    J Bacteriol. 1989 Jan;171(1):558-60 PMID: 2644207
  14. Negative control of cell division by mreB, a gene that functions in determining the rod shape of Escherichia coli cells.
    J Bacteriol. 1989 Jun;171(6):3123-7 PMID: 2656641
  15. New mutations fts-36, lts-33, and ftsW clustered in the mra region of the Escherichia coli chromosome induce thermosensitive cell growth and division.
    J Bacteriol. 1989 Oct;171(10):5523-30 PMID: 2676977
  16. Inhibition of growth of ftsQ, ftsA, and ftsZ mutant cells of Escherichia coli by amplification of a chromosomal region encompassing closely aligned cell division and cell growth genes.
    J Bacteriol. 1989 Nov;171(11):6379-82 PMID: 2553679
  17. Temperature-sensitive mutants of Escherichia coli K-12 with low activities of the L-alanine adding enzyme and the D-alanyl-D-alanine adding enzyme.
    J Bacteriol. 1972 Apr;110(1):35-40 PMID: 4552998
  18. Cell wall peptidoglycan mutants of Escherichia coli K-12: existence of two clusters of genes, mra and mrb, for cell wall peptidoglycan biosynthesis.
    J Bacteriol. 1972 Nov;112(2):950-8 PMID: 4563986
  19. Prediction of protein antigenic determinants from amino acid sequences.
    Proc Natl Acad Sci U S A. 1981 Jun;78(6):3824-8 PMID: 6167991
Article Info
Journal
Journal of bacteriology
Abbr.
J Bacteriol
ISSN
0021-9193
DOI
10.1128/jb.171.11.6375-6378.1989
Published
1989-11-00
Pages
6375-8
Language
English
Region
United States
NLM ID
2985120R
PMCID
PMC210516
Subset
IM
External Links
PubMed source DOI: 10.1128/jb.171.11.6375-6378.1989 PMC Full Text View journal details
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2