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PMID: 2553679 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Inhibition of growth of ftsQ, ftsA, and ftsZ mutant cells of Escherichia coli by amplification of a chromosomal region encompassing closely aligned cell division and cell growth genes.

Journal of bacteriology ·Vol. 171 ·No. 11 ·1989-11-00 ·Pages 6379-82

Jung HK, Ishino F, Matsuhashi M

Abstract

Amplification of a 2.6-kilobase chromosomal fragment of the mra region of Escherichia coli encompassing the ftsI(pbpB) gene and an open reading frame upstream with lethal to E. coli strains with mutations of the flanking cell division genes ftsQ, ftsA, and ftsZ. A shortened fragment in which the major portion of ftsI was deleted also had lethal effects on ftsQ and ftsZ mutants.

MeSH Terms
Bacterial Proteins/genetics Cell Division Chromosomes, Bacterial/physiology Cloning, Molecular Escherichia coli/cytology,genetics,growth & development Gene Amplification Genes, Bacterial Genetic Markers/analysis Mutation Plasmids Restriction Mapping
Chemicals
Bacterial Proteins Genetic Markers
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Jung H K
Institute of Applied Microbiology, University of Tokyo, Japan.
Ishino F
Matsuhashi M
References (14)
14 references, click to expand
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Article Info
Journal
Journal of bacteriology
Abbr.
J Bacteriol
ISSN
0021-9193
DOI
10.1128/jb.171.11.6379-6382.1989
Published
1989-11-00
Pages
6379-82
Language
English
Region
United States
NLM ID
2985120R
PMCID
PMC210517
Subset
IM
External Links
PubMed source DOI: 10.1128/jb.171.11.6379-6382.1989 PMC Full Text View journal details
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