Abstract
Campylobacter coli and Campylobacter jejuni share a limited number of highly conserved DNA sequences with members of the family Enterobacteriaceae. One of these sequences was cloned from C. coli VC167, and the region of homology to the enteric sequences was determined to be confined to a 700-base-pair region. The DNA represented in this clone undergoes a programmed, reversible rearrangement in VC167 that is associated with flagellar antigenic variation.
MeSH Terms
Antigenic Variation
Antigens, Bacterial/genetics,immunology
Base Sequence
Campylobacter/genetics,immunology
Cloning, Molecular
DNA Restriction Enzymes
DNA, Bacterial/genetics
Deoxyribonuclease HindIII
Enterobacteriaceae/genetics,immunology
Flagella/immunology
Genes, Bacterial
Nucleic Acid Hybridization
Sequence Homology, Nucleic Acid
Chemicals
Antigens, Bacterial
DNA, Bacterial
DNA Restriction Enzymes
Deoxyribonuclease HindIII
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Guerry P
Infectious Diseases Department, Naval Medical Research Institute, Bethesda, Maryland 20814.
Logan S M
Trust T J
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