Home LiteratureArticle Details

PMID: 2843821 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Site-specific AT-cluster insertions in the mitochondrial 15S rRNA gene of the yeast S. cerevisiae.

Nucleic acids research ·Vol. 16 ·No. 17 ·1988-09-12 ·Pages 8665-74

Hüttenhofer A, Sakai H, Weiss-Brummer B

Abstract

By comparing the mitochondrial 15S rRNA sequences of four wildtype yeast strains together with their respective secondary structures, with those of the 16S-like ribosomal RNA from other organisms we detected two optional and two invariant AT-clusters. The origin of these clusters is discussed with respect to their roles as possible mobile elements.

MeSH Terms

Adenine Base Sequence DNA Transposable Elements DNA, Mitochondrial/genetics Escherichia coli/genetics Genes, Fungal Models, Molecular Molecular Sequence Data Nucleic Acid Conformation Polymorphism, Genetic RNA, Ribosomal/genetics Saccharomyces cerevisiae/genetics Species Specificity Thymine

Chemicals

DNA Transposable Elements DNA, Mitochondrial RNA, Ribosomal Adenine Thymine

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Hüttenhofer A

Institute für Genetik und Mikrobiologie, Universität München, FRG.

Sakai H

Weiss-Brummer B

References (15)

15 references, click to expand

Mitochondrial genetics. V. Multifactorial mitochondrial crosses involving a mutation conferring paromomycin-resistance in Saccharomyces cerevisiae.
Mol Gen Genet. 1973 Sep 5;125(1):53-90 PMID: 4590264
The mitochondrial genome of wild-type yeast cells. IV. Genes and spacers.
J Mol Biol. 1974 Jul 15;86(4):825-41 PMID: 4610147
DNA sequencing with chain-terminating inhibitors.
Proc Natl Acad Sci U S A. 1977 Dec;74(12):5463-7 PMID: 271968
A system for shotgun DNA sequencing.
Nucleic Acids Res. 1981 Jan 24;9(2):309-21 PMID: 6259625
Cloning in single-stranded bacteriophage as an aid to rapid DNA sequencing.
J Mol Biol. 1980 Oct 25;143(2):161-78 PMID: 6260957
Identification of the paromomycin-resistance mutation in the 15 S rRNA gene of yeast mitochondria.
J Biol Chem. 1982 May 25;257(10):5921-8 PMID: 6279619
Nature of an inserted sequence in the mitochondrial gene coding for the 15S ribosomal RNA of yeast.
Nucleic Acids Res. 1982 Mar 11;10(5):1625-33 PMID: 6280154
Unequal excision of complementary strands is involved in the generation of palindromic repetitions of rho- mitochondrial DNA in yeast.
Cell. 1983 Feb;32(2):391-6 PMID: 6297793
Detailed analysis of the higher-order structure of 16S-like ribosomal ribonucleic acids.
Microbiol Rev. 1983 Dec;47(4):621-69 PMID: 6363901
Yeast mitochondrial genomes consisting of only A.T base pairs replicate and exhibit suppressiveness.
Proc Natl Acad Sci U S A. 1984 Nov;81(22):7156-60 PMID: 6390432
The GC clusters of the mitochondrial genome of yeast and their evolutionary origin.
Gene. 1986;41(1):1-22 PMID: 3009268
Compilation of small ribosomal subunit RNA sequences.
Nucleic Acids Res. 1986;14 Suppl:r73-118 PMID: 3085068
The primary structure of the mitochondrial genome of Saccharomyces cerevisiae--a review.
Gene. 1986;47(2-3):155-77 PMID: 3549452
The AT spacers and the var1 genes from the mitochondrial genomes of Saccharomyces cerevisiae and Torulopsis glabrata: evolutionary origin and mechanism of formation.
Gene. 1987;54(1):1-22 PMID: 3301538
Deletions in the cob gene of yeast mtDNA and their phenotypic effect.
Curr Genet. 1985;10(4):283-90 PMID: 3916810

Article Info

Journal

Nucleic acids research

Abbr.

Nucleic Acids Res

ISSN

0305-1048

DOI

10.1093/nar/16.17.8665

Published

1988-09-12

Pages

8665-74

Language

English

Region

England

NLM ID

0411011

PMCID

PMC338583

Subset

Databases

GENBANK

X07799, X07800

External Links

PubMed source DOI: 10.1093/nar/16.17.8665 PMC Full Text View journal details

Analysis Services

Site-specific AT-cluster insertions in the mitochondrial 15S rRNA gene of the yeast S. cerevisiae.

Contact

WeChat Official Account