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PMID: 293725 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Internal motions in DNA.

Proceedings of the National Academy of Sciences of the United States of America ·Vol. 76 ·No. 12 ·1979-12-00 ·Pages 6341-5

Hogan ME, Jardetzky O

Abstract

We have measured the 31P and 1H NMR parameters of fractionated double-stranded DNA fragments 600, 300, and 150 base pairs long. The results indicate that, inside an intact double helix, both the deoxyribose and the sugar-phosphate backbone of the helix fluctuate substantially from their equilibrium geometry. The time constant for those coupled motions is of the order of 1 nsec.

MeSH Terms
DNA/physiology Deoxyribose Magnetic Resonance Spectroscopy Models, Theoretical Molecular Weight Motion Nucleic Acid Conformation Phosphates Temperature
Chemicals
Phosphates Deoxyribose DNA
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Hogan M E
Jardetzky O
References (18)
18 references, click to expand
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Article Info
Journal
Proceedings of the National Academy of Sciences of the United States of America
Abbr.
Proc Natl Acad Sci U S A
ISSN
0027-8424
DOI
10.1073/pnas.76.12.6341
Published
1979-12-00
Pages
6341-5
Language
English
Region
United States
NLM ID
7505876
PMCID
PMC411860
Subset
IM
External Links
PubMed source DOI: 10.1073/pnas.76.12.6341 PMC Full Text View journal details
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