Home LiteratureArticle Details
PMID: 2993665 Published · ppublish English Comparative Study Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Cross-reactivity between herpes simplex virus glycoprotein B and a 63,000-dalton varicella-zoster virus envelope glycoprotein.

Journal of virology ·Vol. 56 ·No. 1 ·1985-10-00 ·Pages 333-6

Edson CM, Hosler BA, Respess RA, Waters DJ, Thorley-Lawson DA

Abstract

Cross-reactive monoclonal antibodies recognizing both herpes simplex virus (HSV) glycoprotein B and a major 63,000-dalton varicella-zoster virus (VZV) envelope glycoprotein were isolated and found to neutralize VZV infection in vitro. None of the other VZV glycoproteins was recognized by any polyclonal anti-HSV serum tested. These results demonstrate that HSV glycoprotein B and the 63,000-dalton VZV glycoprotein share antigenic epitopes and raise the possibility that these two proteins have a similar function in infection.

MeSH Terms
Antibodies, Monoclonal Cross Reactions Glycoproteins/immunology Herpesvirus 3, Human/immunology Molecular Weight Neutralization Tests Protein Conformation Simplexvirus/immunology Viral Envelope Proteins/immunology Viral Proteins/immunology
Chemicals
Antibodies, Monoclonal Glycoproteins Viral Envelope Proteins Viral Proteins glycoprotein B, Simplexvirus
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Edson C M
Hosler B A
Respess R A
Waters D J
Thorley-Lawson D A
References (34)
34 references, click to expand
  1. Antigenic relationship between varicella-herpes zoster and herpes simplex viruses studied by the gel precipitation reaction.
    Acta Virol. 1971 Jul;15(4):293-300 PMID: 4398080
  2. A rapid procedure for the enrichment of undenaturated, antigenically active herpes simplex virus glycoproteins.
    J Virol Methods. 1984 Feb;8(1-2):27-45 PMID: 6200489
  3. Neutralizing antibody responses to varicella-zoster virus.
    Infect Immun. 1975 Sep;12(3):606-13 PMID: 170206
  4. Rapid isolation of antigens from cells with a staphylococcal protein A-antibody adsorbent: parameters of the interaction of antibody-antigen complexes with protein A.
    J Immunol. 1975 Dec;115(6):1617-24 PMID: 1102604
  5. Identification of a common antigen of herpes simplex virus bovine herpes mammillitis virus, and B virus.
    J Virol. 1978 Jun;26(3):712-7 PMID: 78988
  6. Molecular genetics of herpes simplex virus. II. Mapping of the major viral glycoproteins and of the genetic loci specifying the social behavior of infected cells.
    J Virol. 1979 Feb;29(2):677-97 PMID: 219254
  7. Membrane proteins specified by herpes simplex viruses. III. Role of glycoprotein VP7(B2) in virion infectivity.
    J Virol. 1979 Mar;29(3):1149-58 PMID: 221669
  8. A new mouse myeloma cell line that has lost immunoglobulin expression but permits the construction of antibody-secreting hybrid cell lines.
    J Immunol. 1979 Oct;123(4):1548-50 PMID: 113458
  9. Polypeptides of the Epstein-Barr virus membrane antigen complex.
    J Virol. 1979 Nov;32(2):458-67 PMID: 228070
  10. Structure of the haemagglutinin membrane glycoprotein of influenza virus at 3 A resolution.
    Nature. 1981 Jan 29;289(5796):366-73 PMID: 7464906
  11. Fine mapping of mutations in the fusion-inducing MP strain of herpes simplex virus type 1.
    Virology. 1984 Jul 15;136(1):100-9 PMID: 6330988
  12. Three major glycoprotein genes of varicella-zoster virus whose products have neutralization epitopes.
    J Virol. 1984 Oct;52(1):293-7 PMID: 6207311
  13. Varicella-zoster viral glycoproteins analyzed with monoclonal antibodies.
    J Virol. 1984 Oct;52(1):55-62 PMID: 6090710
  14. Analysis of three late varicella-zoster virus proteins, a 125,000-molecular-weight protein and gp1 and gp3.
    J Virol. 1984 Dec;52(3):953-9 PMID: 6092723
  15. Antigenic and biochemical analysis of gB of herpes simplex virus type 1 and type 2 and of cross-reacting glycoproteins induced by bovine mammillitis virus and equine herpesvirus type 1.
    J Gen Virol. 1985 Feb;66 ( Pt 2):231-47 PMID: 2981966
  16. Varicella-zoster virus envelope glycoproteins: biochemical characterization and identification in clinical material.
    Virology. 1985 Aug;145(1):62-71 PMID: 2990103
  17. A virion-associated glycoprotein essential for infectivity of herpes simplex virus type 1.
    Virology. 1981 Nov;115(1):149-60 PMID: 6270896
  18. Monoclonal antibodies to herpes simplex virus type 1 proteins, including the immediate-early protein ICP 4.
    Infect Immun. 1981 Dec;34(3):684-92 PMID: 6277788
  19. Further evidence for common antigens in herpes simplex and varicella-zoster viruses.
    J Med Virol. 1982;9(1):27-36 PMID: 6278070
  20. Polypeptides of varicella-zoster virus (VZV) and immunological relationship of VZV and herpes simplex virus (HSV).
    J Gen Virol. 1982 Aug;61 (Pt 2):255-69 PMID: 6288857
  21. Endo-beta-N-acetylglucosaminidase H sensitivity of precursors to herpes simplex virus type 1 glycoproteins gB and gC.
    J Virol. 1982 Oct;44(1):241-8 PMID: 6292487
  22. Nucleotide sequences of herpes simplex virus type 1 (HSV-1) affecting virus entry, cell fusion, and production of glycoprotein gb (VP7).
    Virology. 1982 Oct 30;122(2):411-23 PMID: 6293179
  23. Selective cleavage by endo-beta-N-acetylglucosaminidase H at individual glycosylation sites of Sindbis virion envelope glycoproteins.
    J Biol Chem. 1983 Feb 25;258(4):2555-61 PMID: 6401736
  24. GlycoProtein biosynthesis in yeast. protein conformation affects processing of high mannose oligosaccharides on carboxypeptidase Y and invertase.
    J Biol Chem. 1983 Feb 25;258(4):2562-7 PMID: 6401737
  25. O-linked oligosaccharides are acquired by herpes simplex virus glycoproteins in the Golgi apparatus.
    Cell. 1983 Mar;32(3):987-97 PMID: 6299584
  26. Monoclonal antibodies against three major glycoproteins of varicella-zoster virus.
    Infect Immun. 1983 Apr;40(1):381-8 PMID: 6299963
  27. Location and orientation of homologous sequences in the genomes of five herpesviruses.
    J Gen Virol. 1983 Sep;64 (Pt 9):1927-42 PMID: 6310033
  28. Genetic and phenotypic analysis of herpes simplex virus type 1 mutants conditionally resistant to immune cytolysis.
    J Virol. 1983 Sep;47(3):568-85 PMID: 6312082
  29. Varicella virus in HeLa cells.
    Arch Gesamte Virusforsch. 1965;17(3):495-503 PMID: 4286826
  30. Synthesis and processing of glycoproteins of Varicella-Zoster virus (VZV) as studied with monoclonal antibodies to VZV antigens.
    Virology. 1983 Sep;129(2):357-68 PMID: 6312679
  31. Varicella-zoster virus-specific gp140: a highly immunogenic and disulfide-linked structural glycoprotein.
    Virology. 1984 Jan 15;132(1):138-46 PMID: 6320530
  32. Regulation of asparagine-linked oligosaccharide processing. Oligosaccharide processing in Aedes albopictus mosquito cells.
    J Biol Chem. 1984 Feb 25;259(4):2375-82 PMID: 6698972
  33. Carbohydrates of influenza virus. V. Oligosaccharides attached to individual glycosylation sites of the hemagglutinin of fowl plague virus.
    Virology. 1984 Feb;133(1):77-91 PMID: 6422625
  34. Continuous cultures of fused cells secreting antibody of predefined specificity.
    Nature. 1975 Aug 7;256(5517):495-7 PMID: 1172191
Article Info
Journal
Journal of virology
Abbr.
J Virol
ISSN
0022-538X
DOI
10.1128/JVI.56.1.333-336.1985
Published
1985-10-00
Pages
333-6
Language
English
Region
United States
NLM ID
0113724
PMCID
PMC252547
Subset
IM
Grants
NIAID NIH HHS · AI15310 · United States
NIAID NIH HHS · AI21674 · United States
NCI NIH HHS · CA28737 · United States
External Links
PubMed source DOI: 10.1128/JVI.56.1.333-336.1985 PMC Full Text View journal details
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2