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PMID: 2998339 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Ca2+-induced polyphosphoinositide breakdown due to phosphomonoesterase activity in chicken erythrocytes.

The Biochemical journal ·Vol. 231 ·No. 1 ·1985-10-01 ·Pages 179-83

Raval PJ, Allan D

Abstract

Treatment of chicken erythrocytes with ionophore A23187 and Ca2+ caused the breakdown of a large proportion of the cellular polyphosphoinositides. Since no diacylglycerol or phosphatidate was generated, but there was a small increase in the level of phosphatidylinositol, it was concluded that breakdown occurred as a result of phosphomonoesterase activation. Experiments with subcellular fractions showed that the phosphomonoesterase activity was present in the cytosolic fraction of the cells.

MeSH Terms
Animals Calcimycin/pharmacology Calcium/pharmacology Chickens Erythrocytes/drug effects,metabolism Phosphatidylinositol Phosphates Phosphatidylinositols/blood Phosphoric Monoester Hydrolases/blood Subcellular Fractions/drug effects,metabolism
Chemicals
Phosphatidylinositol Phosphates Phosphatidylinositols Calcimycin Phosphoric Monoester Hydrolases Calcium
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Raval P J
Allan D
References (23)
23 references, click to expand
  1. Characteristics of rat liver phosphatidylinositol kinase and its presence in the plasma membrane.
    Biochim Biophys Acta. 1967 Dec 5;144(3):649-58 PMID: 4294903
  2. A rapid method of total lipid extraction and purification.
    Can J Biochem Physiol. 1959 Aug;37(8):911-7 PMID: 13671378
  3. Isocratic separation of some purine nucleotide, nucleoside, and base metabolites from biological extracts by high-performance liquid chromatography.
    J Chromatogr. 1976 Jun 23;121(2):251-62 PMID: 6484
  4. Purification and properties of polyphosphoinositide phosphomonoesterase from rat brain.
    Biochim Biophys Acta. 1977 Feb 9;480(2):390-402 PMID: 13841
  5. Calcium ion-dependent diacylglycerol accumulation in erythrocytes is associated with microvesiculation but not with efflux of potassium ions.
    Biochem J. 1977 Sep 15;166(3):495-9 PMID: 339908
  6. A calcium-activated polyphosphoinositide phosphodiesterase in the plasma membrane of human and rabbit erythrocytes.
    Biochim Biophys Acta. 1978 Apr 4;508(2):277-86 PMID: 205246
  7. Rapid transbilayer diffusion of 1,2-diacylglycerol and its relevance to control of membrane curvature.
    Nature. 1978 Nov 16;276(5685):289-90 PMID: 714162
  8. Hormonally regulated phosphoprotein of turkey erythrocytes: localization to plasma membrane.
    J Cell Biol. 1979 Oct;83(1):1-15 PMID: 229109
  9. Human erythrocyte cytosol phosphatidyl-inositol-bisphosphate phosphatase.
    Biochim Biophys Acta. 1981 Oct 13;661(2):323-33 PMID: 6271223
  10. The Mg2+-activated phosphatidylinositol 4,5-bisphosphate-specific phosphomonoesterase of erythrocyte membrane.
    FEBS Lett. 1982 Jul 19;144(1):16-20 PMID: 6286356
  11. Microvesiculation and sphingomyelinase activation in chicken erythrocytes treated with ionophore A23187 and Ca2+.
    Biochim Biophys Acta. 1982 Dec 8;693(1):53-67 PMID: 6295484
  12. The enzymology of stimulated inositol lipid turnover.
    Cell Calcium. 1982 Oct;3(4-5):295-309 PMID: 6297738
  13. Inositol lipids and membrane function in erythrocytes.
    Cell Calcium. 1982 Oct;3(4-5):451-65 PMID: 6218879
  14. A modified procedure for thin-layer chromatography of phospholipids.
    J Lipid Res. 1982 Dec;23(9):1373-4 PMID: 7161566
  15. Limited breakdown of cytoskeletal proteins by an endogenous protease controls Ca2+-induced membrane fusion events in chicken erythrocytes.
    Biochim Biophys Acta. 1983 May 5;730(2):351-8 PMID: 6303411
  16. Phosphorylation of rat liver nuclear envelopes. II. Characterization of in vitro lipid phosphorylation.
    J Biol Chem. 1983 Aug 10;258(15):9368-73 PMID: 6308005
  17. Evidence for a specific phosphatidylinositol 4-phosphate phosphatase in human erythrocyte membranes.
    J Lipid Res. 1984 Jan;25(1):75-85 PMID: 6323606
  18. Phosphoinositide metabolism and the morphology of human erythrocytes.
    J Cell Biol. 1984 Jun;98(6):1992-8 PMID: 6327723
  19. Calcium-dependent hydrolyses of polyphosphoinositides in human erythrocyte membranes.
    Can J Biochem Cell Biol. 1984 Jun;62(6):363-8 PMID: 6088012
  20. The Ca2+-activated polyphosphoinositide phosphodiesterase of human and rabbit neutrophil membranes.
    Biochem J. 1984 Jul 15;221(2):477-82 PMID: 6089740
  21. Subcellular localisation of inositol lipid kinases in rat liver.
    Biochim Biophys Acta. 1985 May 30;845(2):163-70 PMID: 2986717
  22. Phosphorus assay in column chromatography.
    J Biol Chem. 1959 Mar;234(3):466-8 PMID: 13641241
  23. Chicken erythrocyte membranes: comparison of nuclear and plasma membranes from adults and embryos.
    Exp Cell Res. 1974 Mar 15;84(1):159-66 PMID: 4274149
Article Info
Journal
The Biochemical journal
Abbr.
Biochem J
ISSN
0264-6021
DOI
10.1042/bj2310179
Published
1985-10-01
Pages
179-83
Language
English
Region
England
NLM ID
2984726R
PMCID
PMC1152719
Subset
IM
External Links
PubMed source DOI: 10.1042/bj2310179 PMC Full Text View journal details
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