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Maturation of alpha-L-iduronidase in cultured human fibroblasts.
J Biol Chem. 1981 Mar 25;256(6):3044-8
PMID: 7204389
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UDP-N-acetylglucosamine:glycoprotein N-acetylglucosamine-1-phosphotransferase. Proposed enzyme for the phosphorylation of the high mannose oligosaccharide units of lysosomal enzymes.
J Biol Chem. 1981 May 10;256(9):4275-81
PMID: 6452459
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Enzymatic phosphorylation of lysosomal enzymes in the presence of UDP-N-acetylglucosamine. Absence of the activity in I-cell fibroblasts.
Biochem Biophys Res Commun. 1981 Feb 12;98(3):761-7
PMID: 6452876
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Fibroblasts from patients with I-cell disease and pseudo-Hurler polydystrophy are deficient in uridine 5'-diphosphate-N-acetylglucosamine: glycoprotein N-acetylglucosaminylphosphotransferase activity.
J Clin Invest. 1981 May;67(5):1574-9
PMID: 6262380
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Inhibition of lysosomal alpha-mannosidase by swainsonine, an indolizidine alkaloid isolated from Swainsona canescens.
Biochem J. 1980 Nov 1;191(2):649-51
PMID: 6786280
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Transport and processing of lysosomal enzymes by smooth muscle cells and endothelial cells.
Exp Cell Res. 1981 May;133(1):23-30
PMID: 7238595
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Processing of the phosphorylated recognition marker in lysosomal enzymes. Characterization and partial purification of a microsomal alpha-N-acetylglucosaminyl phosphodiesterase.
J Biol Chem. 1981 Jun 10;256(11):5717-21
PMID: 6263889
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Purification and characterization of rat liver alpha-N-acetylglucosaminyl phosphodiesterase.
J Biol Chem. 1981 Oct 10;256(19):9937-43
PMID: 6268636
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The mannose 6-phosphate receptor of Chinese hamster ovary cells. Compartmentalization of acid hydrolases in mutants with altered receptors.
J Biol Chem. 1981 Oct 25;256(20):10623-7
PMID: 6270123
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Biosynthesis of a lysosomal enzyme. Partial structure of two transient and functionally distinct NH2-terminal sequences in cathepsin D.
J Biol Chem. 1981 Nov 10;256(21):11224-31
PMID: 6116713
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Characterization of a membrane-associated receptor from bovine liver that binds phosphomannosyl residues of bovine testicular beta-galactosidase.
Proc Natl Acad Sci U S A. 1981 Jul;78(7):4289-93
PMID: 6270668
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Lysosomal enzyme targeting. N-Acetylglucosaminylphosphotransferase selectively phosphorylates native lysosomal enzymes.
J Biol Chem. 1981 Dec 10;256(23):11977-80
PMID: 6457829
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Morphologic study of the internalization of a lysosomal enzyme by the mannose 6-phosphate receptor in cultured Chinese hamster ovary cells.
Proc Natl Acad Sci U S A. 1981 Nov;78(11):6967-71
PMID: 6273898
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Cerebroside sulfatase activator deficiency induced metachromatic leukodystrophy.
Am J Hum Genet. 1981 Nov;33(6):900-6
PMID: 6119902
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Phosphorylation of lysosomal enzymes in fibroblasts. Marked deficiency of N-acetylglucosamine-1-phosphotransferase in fibroblasts of patients with mucolipidosis III.
Hoppe Seylers Z Physiol Chem. 1982 Feb;363(2):169-78
PMID: 6460679
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Identification of a variant of mucolipidosis III (pseudo-Hurler polydystrophy): a catalytically active N-acetylglucosaminylphosphotransferase that fails to phosphorylate lysosomal enzymes.
Proc Natl Acad Sci U S A. 1981 Dec;78(12):7773-7
PMID: 6461005
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Biosynthesis of lysosomal hydrolases: their synthesis in bound polysomes and the role of co- and post-translational processing in determining their subcellular distribution.
J Cell Biol. 1982 Apr;93(1):135-43
PMID: 7068751
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Cloning of a cDNA complementary to rat preputial gland beta-glucuronidase mRNA.
Biochem Biophys Res Commun. 1982 Feb 26;104(4):1271-8
PMID: 7041909
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Enhanced breakdown of arylsulfatase A in multiple sulfatase deficiency.
Eur J Biochem. 1982 Apr 1;123(2):317-21
PMID: 6122572
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Synthesis and processing of arylsulfatase A in human skin fibroblasts.
Hoppe Seylers Z Physiol Chem. 1982 Apr;363(4):425-30
PMID: 6122636
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Assay and purification of a solubilized membrane receptor that binds the lysosomal enzyme alpha-L-iduronidase.
Arch Biochem Biophys. 1982 Apr 1;214(2):681-7
PMID: 7092215
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Deficiency of UDP-N-acetylglucosamine:lysosomal enzyme N-acetylglucosamine-1-phosphotransferase in organs of I-cell patients.
Biochem Biophys Res Commun. 1982 Apr 14;105(3):1052-8
PMID: 6212058
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Is there a mechanism for introducing acid hydrolases into liver lysosomes that is independent of mannose 6-phosphate recognition? Evidence from I-cell disease.
Biochem Biophys Res Commun. 1982 Apr 14;105(3):814-20
PMID: 6807313
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The internal reticular apparatus of Camillo Golgi: a complex, heterogeneous organelle, enriched in acid, neutral, and alkaline phosphatases, and involved in glycosylation, secretion, membrane flow, lysosome formation, and intracellular digestion.
J Histochem Cytochem. 1982 Jul;30(7):717-33
PMID: 6286754
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UDP-N-acetylglucosamine:lysosomal enzyme precursor N-acetylglucosamine-1-phosphotransferase. Partial purification and characterization of the rat liver Golgi enzyme.
J Biol Chem. 1982 Oct 25;257(20):12322-31
PMID: 6288715
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Molecular defect in combined beta-galactosidase and neuraminidase deficiency in man.
Proc Natl Acad Sci U S A. 1982 Aug;79(15):4535-9
PMID: 6812049
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Demonstration of the heterozygous state for I-cell disease and pseudo-Hurler polydystrophy by assay of N-acetylglucosaminylphosphotransferase in white blood cells and fibroblasts.
Am J Hum Genet. 1982 Sep;34(5):717-29
PMID: 6289658
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Synthesis of beta-hexosaminidase in cell-free translation and in intact fibroblasts: an insoluble precursor alpha chain in a rare form of Tay-Sachs disease.
Proc Natl Acad Sci U S A. 1982 Oct;79(20):6360-4
PMID: 6959123
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Mucolipidosis III is genetically heterogeneous.
Proc Natl Acad Sci U S A. 1982 Dec;79(23):7420-4
PMID: 6961420
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Biosynthesis of acid alpha-glucosidase in late-onset forms of glycogenosis type II (Pompe's disease).
FEBS Lett. 1982 Dec 13;150(1):69-76
PMID: 6761145
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Evidence for extensive subcellular organization of asparagine-linked oligosaccharide processing and lysosomal enzyme phosphorylation.
J Biol Chem. 1983 Mar 10;258(5):3159-65
PMID: 6402509
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Identification and characterization of cells deficient in the mannose 6-phosphate receptor: evidence for an alternate pathway for lysosomal enzyme targeting.
Proc Natl Acad Sci U S A. 1983 Feb;80(3):775-9
PMID: 6298775
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Synthesis and maturation of cross-reactive glycoprotein in fibroblasts deficient in arylsulfatase A activity.
Biochem Biophys Res Commun. 1983 Apr 15;112(1):198-205
PMID: 6132606
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Immunological evidence for deficiency in an activator protein for sulfatide sulfatase in a variant form of metachromatic leukodystrophy.
Proc Natl Acad Sci U S A. 1983 May;80(10):3074-7
PMID: 6134282
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Biosynthesis and transport of cathepsin D in cultured human fibroblasts.
J Cell Biol. 1983 Jul;97(1):1-5
PMID: 6863385
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Mucolipidosis II and III. The genetic relationships between two disorders of lysosomal enzyme biosynthesis.
J Clin Invest. 1983 Sep;72(3):1016-23
PMID: 6309902
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Juvenile and adult metachromatic leukodystrophy: partial restoration of arylsulfatase A (cerebroside sulfatase) activity by inhibitors of thiol proteinases.
Proc Natl Acad Sci U S A. 1983 Oct;80(19):6066-70
PMID: 6136972
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Translocation of a lysosomal enzyme across the microsomal membrane requires signal recognition particle.
Biochem Biophys Res Commun. 1983 Aug 30;115(1):275-80
PMID: 6137219
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Biosynthesis and maturation of arylsulfatase B in normal and mutant cultured human fibroblasts.
J Biol Chem. 1983 Dec 10;258(23):14322-6
PMID: 6417138
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Detection of early changes in androgen-induced mouse renal beta-glucuronidase messenger ribonucleic acid using cloned complementary deoxyribonucleic acid.
Biochemistry. 1983 Dec 20;22(26):6049-53
PMID: 6689271
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The mannose-6-phosphate receptor for lysosomal enzymes is concentrated in cis Golgi cisternae.
Cell. 1984 Feb;36(2):295-307
PMID: 6319015
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Processing of human beta-galactosidase in GM1-gangliosidosis and Morquio B syndrome.
J Biol Chem. 1984 Feb 10;259(3):1974-7
PMID: 6420416
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Golgi apparatus, GERL, and lysosomes of neurons in rat dorsal root ganglia, studied by thick section and thin section cytochemistry.
J Cell Biol. 1971 Sep;50(3):859-86
PMID: 4329159
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A hypothesis for I-cell disease: defective hydrolases that do not enter lysosomes.
Biochem Biophys Res Commun. 1972 Nov 15;49(4):992-9
PMID: 4345092
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Phosphohexosyl components of a lysosomal enzyme are recognized by pinocytosis receptors on human fibroblasts.
Proc Natl Acad Sci U S A. 1977 May;74(5):2026-30
PMID: 266721
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AB variant of infantile GM2 gangliosidosis: deficiency of a factor necessary for stimulation of hexosaminidase A-catalyzed degradation of ganglioside GM2 and glycolipid GA2.
Proc Natl Acad Sci U S A. 1978 Aug;75(8):3979-83
PMID: 99746
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Excretion-reuptake route of beta-hexosaminidase in normal and I-cell disease cultured fibroblasts.
J Clin Invest. 1979 Apr;63(4):595-601
PMID: 438323
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Biosynthesis of lysosomal enzymes in fibroblasts. Synthesis as precursors of higher molecular weight.
J Biol Chem. 1980 May 25;255(10):4937-45
PMID: 6989821
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Chloroquine inhibits lysosomal enzyme pinocytosis and enhances lysosomal enzyme secretion by impairing receptor recycling.
J Cell Biol. 1980 Jun;85(3):839-52
PMID: 7190150
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Biosynthesis and maturation of alpha-N-acetylglucosaminidase in normal and Sanfilippo B-fibroblasts.
Am J Hum Genet. 1984 Jan;36(1):93-100
PMID: 6421152
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Cloning a cDNA for the lysosomal alpha-glucosidase.
Biochem Biophys Res Commun. 1984 Feb 29;119(1):252-8
PMID: 6367744
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Role of basic residues in the phosphorylation of synthetic peptides by myosin light chain kinase.
Proc Natl Acad Sci U S A. 1983 Dec;80(24):7471-5
PMID: 6584865
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Ultrastructural localization of the mannose 6-phosphate receptor in rat liver.
J Cell Biol. 1984 Jun;98(6):2047-54
PMID: 6327724
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Detergent dissociation of bovine liver phosphomannosyl binding protein.
J Cell Biochem. 1984;24(4):319-30
PMID: 6088561
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cDNA clone for the alpha-chain of human beta-hexosaminidase: deficiency of alpha-chain mRNA in Ashkenazi Tay-Sachs fibroblasts.
Proc Natl Acad Sci U S A. 1984 Sep;81(17):5394-8
PMID: 6236461
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Isolation of cDNA clones for human beta-glucocerebrosidase using the lambda gt11 expression system.
Biochem Biophys Res Commun. 1984 Sep 17;123(2):574-80
PMID: 6091633
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Five related Lebanese individuals with high plasma lysosomal hydrolases: a new defect in mannose-6-phosphate receptor recognition?
Am J Hum Genet. 1984 Sep;36(5):1001-14
PMID: 6238528
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Lysosomal enzyme phosphorylation. Recognition of a protein-dependent determinant allows specific phosphorylation of oligosaccharides present on lysosomal enzymes.
J Biol Chem. 1984 Dec 10;259(23):14663-71
PMID: 6094568
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The mannose 6-phosphate receptor: function, biosynthesis and translocation.
Biol Cell. 1984;51(2):207-14
PMID: 6240303
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Isolation of cDNA clones coding for the beta subunit of human beta-hexosaminidase.
Proc Natl Acad Sci U S A. 1985 Feb;82(4):1184-8
PMID: 2579389
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Molecular cloning of a cDNA for human alpha-L-fucosidase.
Proc Natl Acad Sci U S A. 1985 Feb;82(4):1262-5
PMID: 2983333
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Defects in synthesis, phosphorylation, and maturation of acid alpha-glucosidase in glycogenosis type II.
J Biol Chem. 1985 Jul 15;260(14):8336-41
PMID: 3159730
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Lysosomal enzyme binding to mouse P388D1 macrophage membranes lacking the 215-kDa mannose 6-phosphate receptor: evidence for the existence of a second mannose 6-phosphate receptor.
Proc Natl Acad Sci U S A. 1985 Jul;82(13):4428-32
PMID: 3160044
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Cloning and sequence analysis of cDNA for human cathepsin D.
Proc Natl Acad Sci U S A. 1985 Aug;82(15):4910-4
PMID: 3927292
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Assembly of asparagine-linked oligosaccharides.
Annu Rev Biochem. 1985;54:631-64
PMID: 3896128
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Internalization of blocking antibodies against mannose-6-phosphate specific receptors.
EMBO J. 1985 Jul;4(7):1725-30
PMID: 3161725
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Purification and characterization of a cation-dependent mannose 6-phosphate receptor from murine P388D1 macrophages and bovine liver.
J Biol Chem. 1985 Oct 5;260(22):12008-14
PMID: 2931431
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Lysosomal enzyme phosphorylation in human fibroblasts. Kinetic parameters offer a biochemical rationale for two distinct defects in the uridine diphospho-N-acetylglucosamine:lysosomal enzyme precursor N-acetylglucosamine-1-phosphotransferase.
J Clin Invest. 1985 Dec;76(6):2191-5
PMID: 3001146