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PMID: 3003687 Published · ppublish English Journal Article

The complete coding sequence of the human raf oncogene and the corresponding structure of the c-raf-1 gene.

Nucleic acids research ·Vol. 14 ·No. 2 ·1986-01-24 ·Pages 1009-15

Bonner TI, Oppermann H, Seeburg P, Kerby SB, Gunnell MA, Young AC, Rapp UR

Abstract

The complete 648 amino acid sequence of the human raf oncogene was deduced from the 2977 nucleotide sequence of a fetal liver cDNA. The cDNA has been used to obtain clones which extend the human c-raf-1 locus by an additional 18.9 kb at the 5' end and contain all the remaining coding exons.

MeSH Terms
Amino Acid Sequence Base Sequence Cloning, Molecular DNA/analysis DNA Restriction Enzymes Female Humans Liver/embryology,metabolism Neoplasm Proteins/genetics Oncogenes Placenta/metabolism Pregnancy RNA, Messenger/genetics Structure-Activity Relationship
Chemicals
Neoplasm Proteins RNA, Messenger DNA DNA Restriction Enzymes
Authors & Affiliations
7 authors, click to expand affiliations / ORCID
Bonner T I
Oppermann H
Seeburg P
Kerby S B
Gunnell M A
Young A C
Rapp U R
References (19)
19 references, click to expand
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Article Info
Journal
Nucleic acids research
Abbr.
Nucleic Acids Res
ISSN
0305-1048
DOI
10.1093/nar/14.2.1009
Published
1986-01-24
Pages
1009-15
Language
English
Region
England
NLM ID
0411011
PMCID
PMC339479
Subset
IM
Databases
GENBANK
X03484
External Links
PubMed source DOI: 10.1093/nar/14.2.1009 PMC Full Text View journal details
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