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PMID: 3058297 Published · ppublish English Journal Article Review

Laboratory, clinical, and epidemiological aspects of coagulase-negative staphylococci.

Clinical microbiology reviews ·Vol. 1 ·No. 3 ·1988-07-00 ·Pages 281-99

Pfaller MA, Herwaldt LA

Abstract

Coagulase-negative staphylococci, particularly Staphylococcus epidermidis, are increasingly important causes of nosocomial infection. Microbiologists and clinicians no longer can afford to disregard clinical isolates of coagulase-negative staphylococci as contaminants. Accurate species identification and antimicrobial susceptibility testing, in a clinically relevant time frame, are important aids in the diagnosis and management of serious coagulase-negative staphylococcal infections. Emphasis in the clinical laboratory should be placed on the routine identification of S. epidermidis and Staphylococcus saprophyticus, with identification of other species of coagulase-negative staphylococci as clinically indicated. The application of newer techniques, such as plasmid analysis and tests for slime production and adherence, contribute to our understanding of the epidemiology and pathogenesis of coagulase-negative staphylococci and may also be helpful in establishing the diagnosis of infection.

MeSH Terms
Coagulase/metabolism Cross Infection/epidemiology,etiology Epidemiologic Methods Humans Staphylococcal Infections/epidemiology,etiology Staphylococcus/classification,enzymology,isolation & purification
Chemicals
Coagulase
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Pfaller M A
Veterans Administration Medical Center, Iowa City, Iowa.
Herwaldt L A
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Article Info
Journal
Clinical microbiology reviews
Abbr.
Clin Microbiol Rev
ISSN
0893-8512
DOI
10.1128/CMR.1.3.281
Published
1988-07-00
Pages
281-99
Language
English
Region
United States
NLM ID
8807282
PMCID
PMC358051
Subset
IM
External Links
PubMed source DOI: 10.1128/CMR.1.3.281 PMC Full Text View journal details
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