In vitro activities of ofloxacin and four other new quinoline-carboxylic acids against Chlamydia trachomatis.

Antimicrobial agents and chemotherapy ·Vol. 32 ·No. 11 ·1988-11-00 ·Pages 1735-7

Nagayama A, Nakao T, Taen H

Abstract

The in vitro activities of five new quinoline-carboxylic acids against 2 reference strains and 45 clinical isolates of Chlamydia trachomatis of genital origin were compared with the activities of minocycline and doxycycline. Ofloxacin was the third most active agent (after the two tetracyclines), followed by ciprofloxacin, NY-198, and AM-833.

MeSH Terms

Anti-Infective Agents/pharmacology Chlamydia trachomatis/drug effects,growth & development Ciprofloxacin/analogs & derivatives,pharmacology Doxycycline/pharmacology Fleroxacin Fluoroquinolones Minocycline/pharmacology Norfloxacin/pharmacology Ofloxacin/pharmacology Quinolones

Chemicals

Anti-Infective Agents Fluoroquinolones Quinolones Ciprofloxacin Ofloxacin Minocycline lomefloxacin Norfloxacin Doxycycline Fleroxacin

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Nagayama A

Department of Microbiology, Saga Medical School, Japan.

Nakao T

Taen H

References (18)

18 references, click to expand

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Article Info

Journal

Antimicrobial agents and chemotherapy

Abbr.

Antimicrob Agents Chemother

ISSN

0066-4804

DOI

10.1128/AAC.32.11.1735

Published

1988-11-00

Pages

1735-7

Language

English

Region

United States

NLM ID

0315061

PMCID

PMC175961

Subset

External Links

PubMed source DOI: 10.1128/AAC.32.11.1735 PMC Full Text View journal details

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In vitro activities of ofloxacin and four other new quinoline-carboxylic acids against Chlamydia trachomatis.

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