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PMID: 321437 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S.

Tn402: a new transposable element determining trimethoprim resistance that inserts in bacteriophage lambda.

Journal of bacteriology ·Vol. 129 ·No. 3 ·1977-03-00 ·Pages 1632-5

Shapiro JA, Sporn P

Abstract

We have found that the trimethoprim resistance determinant of the IncP plasmid R751 (Jacob et al., 1977; Jobanputra and Datta, 1974) transposes to bacteriophage lambda. We call this transposable element Tn402.

MeSH Terms
Coliphages DNA, Viral Drug Resistance, Microbial Escherichia coli/drug effects Lysogeny R Factors Transduction, Genetic Trimethoprim/pharmacology
Chemicals
DNA, Viral Trimethoprim
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Shapiro J A
Sporn P
References (9)
9 references, click to expand
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  2. Trimethoprim R factors in enterobacteria from clinical specimens.
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  3. The galactose operon of E. coli K-12. II. A deletion analysis of operon structure and polarity.
    Genetics. 1969 Jun;62(2):249-64 PMID: 4905872
  4. Site specific recA--independent recombination between bacterial plasmids: involvement of palindromes at the recombinational loci.
    Proc Natl Acad Sci U S A. 1975 Apr;72(4):1373-7 PMID: 1093180
  5. Mutagenesis by insertion of a drug-resistance element carrying an inverted repetition.
    J Mol Biol. 1975 Oct 5;97(4):561-75 PMID: 1102715
  6. Translocation of a plasmid DNA sequence which mediates ampicillin resistance: molecular nature and specificity of insertion.
    Proc Natl Acad Sci U S A. 1975 Sep;72(9):3623-7 PMID: 1103150
  7. Transposition of a deoxyribonucleic acid sequence encoding trimethoprim and streptomycin resistances from R483 to other replicons.
    J Bacteriol. 1976 Mar;125(3):800-10 PMID: 767328
  8. Transposition of R factor genes to bacteriophage lambda.
    Proc Natl Acad Sci U S A. 1975 Sep;72(9):3628-32 PMID: 1059152
  9. Mapping of deletions and substitutions in heteroduplex DNA molecules of bacteriophage lambda by electron microscopy.
    Science. 1969 Mar 21;163(3873):1343-8 PMID: 5765116
Article Info
Journal
Journal of bacteriology
Abbr.
J Bacteriol
ISSN
0021-9193
DOI
10.1128/jb.129.3.1632-1635.1977
Published
1977-03-00
Pages
1632-5
Language
English
Region
United States
NLM ID
2985120R
PMCID
PMC235145
Subset
IM
External Links
PubMed source DOI: 10.1128/jb.129.3.1632-1635.1977 PMC Full Text View journal details
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