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PMID: 321973 Published · ppublish ger English Abstract Journal Article Review

[Membrane permeability and antibiotic resistance in bacteria].

Membranpermeation und Antibiotika-Resistenz bei Bakterien

Die Naturwissenschaften ·Vol. 64 ·No. 3 ·1977-03-00 ·Pages 126-32

Braun V

Abstract

The resistance of mainly gram-negative bacteria against antibiotics is discussed with respect to new discoveries on the permeability barrier of the outer membrane. Proteins originally characterized as virus receptors have been found to be involved in the translocation of certain substrates across the membrane. Antibiotics can reach their target by the same "pores".

MeSH Terms
Anti-Bacterial Agents/pharmacology Bacteria/drug effects,ultrastructure Bacterial Proteins/physiology Bacteriophages/metabolism Cell Membrane/physiology,ultrastructure Cell Membrane Permeability/drug effects Cell Wall/physiology Diffusion Drug Resistance, Microbial Iron/metabolism Lipopolysaccharides/physiology Membrane Proteins/physiology Models, Biological Mutation Plasmids Protein Binding Receptors, Drug/physiology
Chemicals
Anti-Bacterial Agents Bacterial Proteins Lipopolysaccharides Membrane Proteins Receptors, Drug Iron
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Braun V
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55 references, click to expand
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Article Info
Journal
Die Naturwissenschaften
Abbr.
Naturwissenschaften
ISSN
0028-1042
DOI
10.1007/BF00450570
Published
1977-03-00
Pages
126-32
Language
ger
Region
Germany
NLM ID
0400767
Subset
IM
External Links
PubMed source DOI: 10.1007/BF00450570 View journal details
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