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PMID: 327945 Published · ppublish English Journal Article

Evaluation of Vickers-Trexler isolator in children undergoing bone marrow transplantation.

Archives of disease in childhood ·Vol. 52 ·No. 7 ·1977-07-00 ·Pages 563-8

Watson JG, Rogers TR, Selwyn S, Smith RG

Abstract

Four children, 5 months to 15 years of age, underwent bone marrow transplantation in Vickers-Trexler isolator tents. Two grafts were elective. During 170 days of isolation no clinical infections due to exogenous micro-organisms developed despite severe immunodeficiency. The decontamination regimen and sterile procedures used, as well as the microbiological results, are described. This form of isolation in paediatric practice was found to be highly acceptable to both patients and staff.

MeSH Terms
Adolescent Bone Marrow Cells Bone Marrow Transplantation Child Evaluation Studies as Topic Fanconi Anemia/therapy Female Humans Immunologic Deficiency Syndromes/therapy Infant Male Patient Isolation/nursing Patient Isolators/instrumentation Pediatric Nursing/methods
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Watson J G
Rogers T R
Selwyn S
Smith R G
References (11)
11 references, click to expand
  1. Transplantation of bone-marrow cells and fetal thymus in an infant with lymphopenic immunological deficiency.
    Lancet. 1969 Jun 21;1(7608):1223-7 PMID: 4182410
  2. Infectious complications in bone marrow transplant patients.
    Br Med J. 1971 Jan 2;1(5739):18-23 PMID: 4395326
  3. Protected environments and prophylactic antibiotics. A prospective controlled study of their utility in the therapy of acute leukemia.
    N Engl J Med. 1973 Mar 8;288(10):477-83 PMID: 4630706
  4. Marrow transplantation in treatment of children with aplastic anaemia or acute leukaemia.
    Arch Dis Child. 1976 Jun;51(6):403-10 PMID: 8016
  5. Bone-marrow transplantation (second of two parts).
    N Engl J Med. 1975 Apr 24;292(17):895-902 PMID: 235092
  6. The gnotobiotic animal as a tool in the study of host microbial relationships.
    Bacteriol Rev. 1971 Dec;35(4):390-429 PMID: 4945725
  7. Defective bactericidal activity of monocytes in fatal granulomatous disease.
    Blood. 1969 Jun;33(6):813-20 PMID: 4890921
  8. Analysis of studies on protected environments and prophylactic antibiotics in adult acute leukemia.
    Eur J Cancer. 1975 Aug;11suppl:57-66 PMID: 815093
  9. Technique of bone marrow transplantation.
    Proc R Soc Med. 1975 Sep;68(9):580-2 PMID: 1105599
  10. Plastic isolators for treatment of acute leukaemia patients under "germ-free" conditions.
    Br Med J. 1975 Dec 6;4(5996):549-52 PMID: 1203666
  11. Defective candidacidal capacity of polymorphonuclear leukocytes in chronic granulomatous disease of childhood.
    J Pediatr. 1969 Aug;75(2):300-3 PMID: 5795350
Article Info
Journal
Archives of disease in childhood
Abbr.
Arch Dis Child
ISSN
1468-2044
Published
1977-07-00
Pages
563-8
Language
English
Region
England
NLM ID
0372434
PMCID
PMC1544761
Subset
IM
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