Effects of anti-EGF serum on newborn mice.

Experientia ·Vol. 44 ·No. 3 ·1988-03-15 ·Pages 249-51

Zschiesche W, Eckert K

Abstract

Administration of anti-EGF serum to newborn mice led to delay of eyelid opening and incisor tooth eruption, acceleration of hair growth and delay of weight gain. These results indicate that in the first week after birth EGF still has a physiological function, which can be abrogated by anti-EGF serum.

MeSH Terms

Animals Animals, Newborn/physiology Body Weight Cell Differentiation Ear/growth & development Epidermal Cells Epidermal Growth Factor/physiology Eyelids/growth & development Hair/growth & development Immunologic Techniques Mice Tooth/growth & development

Chemicals

Epidermal Growth Factor

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Zschiesche W

Akademie der Wissenschaften der DDR, Zentralinstitut für Molekularbiologie, Berlin.

Eckert K

References (17)

17 references, click to expand

A physiological role of epidermal growth factor in male reproductive function.
Science. 1986 Aug 29;233(4767):975-7 PMID: 3090686
Cleavage of structural proteins during the assembly of the head of bacteriophage T4.
Nature. 1970 Aug 15;227(5259):680-5 PMID: 5432063
Enhancement of epidermal regeneration by biosynthetic epidermal growth factor.
J Exp Med. 1986 May 1;163(5):1319-24 PMID: 3486247
Effects of epidermal growth factor on hair growth in the mouse.
J Endocrinol. 1981 Feb;88(2):293-9 PMID: 6970792
Epidermal growth factor and a new derivative. Rapid isolation procedures and biological and chemical characterization.
J Biol Chem. 1972 Dec 10;247(23):7609-11 PMID: 4636326
Evidence for physiological function of epidermal growth factor: pregestational sialoadenectomy of mice decreases milk production and increases offspring mortality during lactation period.
Proc Natl Acad Sci U S A. 1984 Oct;81(19):6059-63 PMID: 6385007
Epidermal growth factor: effects of androgens and adrenergic agents.
Endocrinology. 1974 Sep;95(3):776-82 PMID: 4368688
Immunohistochemical localization of epidermal growth factor in rat and man.
Histochemistry. 1986;85(5):389-94 PMID: 3536807
Embryonal carcinoma cell growth and differentiation. Production of and response to molecules with transforming growth factor activity.
Exp Cell Res. 1983 Jan;143(1):143-52 PMID: 6297938
Pancreatic cancer in the Syrian hamster induced by N-nitrosobis(2-oxopropyl)-amine: cocarcinogenic effect of epidermal growth factor.
Cancer Res. 1986 Jun;46(6):2954-7 PMID: 3009003
Physiological effects of transforming growth factor in the newborn mouse.
Science. 1985 Aug 16;229(4714):673-5 PMID: 3860952
Immunocytochemical localization of epidermal growth factor in mouse kidney.
J Histochem Cytochem. 1986 Sep;34(9):1155-60 PMID: 2426343
Growth of mammary epithelial cells in breast-cancer biopsies correlates with EGF binding.
Int J Cancer. 1987 Mar 15;39(3):279-82 PMID: 3493223
Role of epidermal growth factor in carcinogenesis.
Cancer Res. 1986 Mar;46(3):1030-7 PMID: 3002608
Enzyme-linked immunosorbent assay (ELISA). Quantitative assay of immunoglobulin G.
Immunochemistry. 1971 Sep;8(9):871-4 PMID: 5135623
Epidermal growth factor.
Annu Rev Biochem. 1979;48:193-216 PMID: 382984
Epidermal growth factor (EGF) accelerates the maturation of fetal mouse intestinal mucosa in utero.
Experientia. 1982 Sep 15;38(9):1096-7 PMID: 6290260

Article Info

Journal

Experientia

Abbr.

Experientia

ISSN

0014-4754

DOI

10.1007/BF01941725

Published

1988-03-15

Pages

249-51

Language

English

Region

Switzerland

NLM ID

0376547

Subset

External Links

PubMed source DOI: 10.1007/BF01941725

Analysis Services

Effects of anti-EGF serum on newborn mice.

Contact

WeChat Official Account