The origin of the vasopressinergic and oxytocinergic fibres of the external region of the median eminence of the rat hypophysis.

Cell and tissue research ·Vol. 180 ·No. 4 ·1977-06-13 ·Pages 443-52

Vandesande F, Dierickx K, De Mey J

Abstract

The origin of the vasopressinergic and oxytocinergic nerve fibres of the external region of the rat median eminence was investigated by means of hypothalamic lesions, adrenalectomy and immunocytochemistry. The results obtained in bilaterally adrenalectomized animals with complete, or incomplete, destruction of the suprachiasmatic nuclei showed that, at least, the great majority of the vasopressinergic and oxytocinergic nerve fibres of the external region of the rat median eminence do not originate from the suprachiasmatic nuclei. From the observations obtained in bilaterally adrenalectomized animals with total or subtotal destruction of both paraventricular hypothalamic nuclei, it appears that the paraventricular nuclei must be the origin of (nearly) all the vasopressinergic and oxytocinergic nerve fibres of the external region of the rat median eminence. The results strongly suggest that both types of fibres originate from all parts of the paraventricular nuclei.

MeSH Terms

Adrenalectomy Animals Hypothalamo-Hypophyseal System/cytology Hypothalamus Immunologic Techniques Median Eminence/cytology Oxytocin Paraventricular Hypothalamic Nucleus Rats/anatomy & histology Vasopressins

Chemicals

Vasopressins Oxytocin

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Vandesande F

Dierickx K

De Mey J

References (17)

17 references, click to expand

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Article Info

Journal

Cell and tissue research

Abbr.

Cell Tissue Res

ISSN

0302-766X

DOI

10.1007/BF00220167

Published

1977-06-13

Pages

443-52

Language

English

Region

Germany

NLM ID

0417625

Subset

External Links

PubMed source DOI: 10.1007/BF00220167 View journal details

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The origin of the vasopressinergic and oxytocinergic fibres of the external region of the median eminence of the rat hypophysis.

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