Home LiteratureArticle Details
PMID: 3311027 Published · ppublish English Journal Article Review

Biochemistry of bile secretion.

The Biochemical journal ·Vol. 244 ·No. 2 ·1987-06-01 ·Pages 249-61

Coleman R

Abstract

暂无摘要

MeSH Terms
Animals Anions/metabolism Bile/metabolism Bile Acids and Salts/metabolism Bile Ducts/physiology Cholesterol/metabolism Endocytosis Humans Lipid Metabolism Liver/physiology
Chemicals
Anions Bile Acids and Salts Cholesterol
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Coleman R
Department of Biochemistry, University of Birmingham, U.K.
References (132)
132 references, click to expand
  1. Phospholipid degradation in, and protein content of, rat fistula bile. Contamination of bile with pancreatic juice.
    J Hepatol. 1986;3(2):233-40 PMID: 2432111
  2. Mechanisms of experimentally induced intrahepatic cholestasis.
    Prog Liver Dis. 1986;8:161-78 PMID: 3012636
  3. Hepatic bile salt transport. A review of subcellular binding sites.
    Biochem Soc Trans. 1981 Feb;9(1):170-4 PMID: 7011873
  4. Receptor-mediated biliary transport of immunoglobulin A and asialoglycoprotein: sorting and missorting of ligands revealed by two radiolabeling methods.
    J Cell Biol. 1984 Jan;98(1):79-89 PMID: 6323485
  5. The effects of colchicine on secretion into bile of bile salts, phospholipids, cholesterol and plasma membrane enzymes: bile salts are secreted unaccompanied by phospholipids and cholesterol.
    Biochem J. 1984 Jun 15;220(3):723-31 PMID: 6466298
  6. Synthesis and transport characteristics of photoaffinity probes for the hepatocyte bile acid transport system.
    J Biol Chem. 1983 Jul 25;258(14):8890-5 PMID: 6863315
  7. Intracellular bile acid transport in rat liver as visualized by electron microscope autoradiography using a bile acid analogue.
    Am J Physiol. 1983 Nov;245(5 Pt 1):G681-9 PMID: 6638192
  8. Abnormal secretion of proteins into bile from colchicine-treated isolated perfused rat livers.
    Biochem J. 1983 Nov 15;216(2):409-14 PMID: 6661206
  9. Selective biliary lipid secretion at low bile-salt-output rates in the isolated perfused rat liver. Effects of phalloidin.
    Biochem J. 1986 Jul 1;237(1):301-4 PMID: 3800886
  10. A biochemical dissection of the functional polarity of the plasma membrane of the hepatocyte.
    Biochim Biophys Acta. 1980 May 27;604(1):27-64 PMID: 6992871
  11. Functional hepatocellular heterogeneity.
    Hepatology. 1982 May-Jun;2(3):385-95 PMID: 7042508
  12. Biogenesis of the polymeric IgA receptor in rat hepatocytes. I. Kinetic studies of its intracellular forms.
    J Cell Biol. 1985 Apr;100(4):1248-54 PMID: 3920224
  13. Intrahepatic sources of biliary-like micelles.
    Biochim Biophys Acta. 1986 Mar 21;876(1):1-12 PMID: 3947663
  14. Taurocholate transport by rat liver sinusoidal membrane vesicles: evidence of sodium cotransport.
    Hepatology. 1982 Sep-Oct;2(5):572-9 PMID: 7118069
  15. No increase of biliary permeability in ethinylestradiol-treated rats.
    Gastroenterology. 1983 Oct;85(4):808-14 PMID: 6884706
  16. Isolated perfused rat liver technique.
    Methods Enzymol. 1981;77:81-94 PMID: 6799738
  17. Biliary secretion of sodium fluorescein in primary monolayer cultures of adult rat hepatocytes and its stimulation by nicotinamide.
    J Cell Sci. 1982 Aug;56:233-44 PMID: 6220021
  18. New concepts of mechanisms of hepatocyte bile formation.
    Physiol Rev. 1980 Apr;60(2):303-26 PMID: 6247725
  19. Mechanisms of taurocholate transport in canalicular and basolateral rat liver plasma membrane vesicles. Evidence for an electrogenic canalicular organic anion carrier.
    J Biol Chem. 1984 Aug 25;259(16):10614-22 PMID: 6469975
  20. Identification and characterization of a bile acid receptor in isolated liver surface membranes.
    J Clin Invest. 1976 Feb;57(2):496-508 PMID: 3520
  21. Preparation of mammalian hepatocytes.
    Methods Enzymol. 1981;77:130-7 PMID: 6276652
  22. Isolated rat hepatocyte couplets: a primary secretory unit for electrophysiologic studies of bile secretory function.
    Proc Natl Acad Sci U S A. 1984 Oct;81(20):6516-20 PMID: 6149546
  23. Hepatocytes of Zones 1 and 3 conjugate sulfobromophthalein with glutathione.
    Hepatology. 1984 May-Jun;4(3):467-76 PMID: 6724515
  24. Uptake of galactose, ouabain and taurocholate into centrilobular and periportal enriched hepatocyte subpopulations.
    J Pharmacol Exp Ther. 1981 Mar;216(3):634-9 PMID: 7205641
  25. Hepatobiliary clearance of IgA immune complexes formed in the circulation.
    Hepatology. 1982 May-Jun;2(3):328-33 PMID: 7076115
  26. Transfer of cholesterol from its site of synthesis to the plasma membrane.
    J Biol Chem. 1984 Dec 10;259(23):14624-30 PMID: 6501312
  27. Biliary excretion of drugs and other xenobiotics.
    Annu Rev Pharmacol Toxicol. 1978;18:81-96 PMID: 348071
  28. Coordinate secretion of acid hydrolases in rat bile.
    J Clin Invest. 1979 Oct;64(4):948-54 PMID: 113427
  29. Preparation of a low-density species of endocytic vesicle containing immunoglobulin A.
    Biochem J. 1983 Sep 15;214(3):823-7 PMID: 6626159
  30. Collection of metabolites in bile and urine from the rat.
    Methods Enzymol. 1981;77:21-30 PMID: 6799735
  31. Hepatocyte heterogeneity in glutamine and ammonia metabolism and the role of an intercellular glutamine cycle during ureogenesis in perfused rat liver.
    Eur J Biochem. 1983 Jun 15;133(2):269-75 PMID: 6852039
  32. Subcellular distribution of bile acids, bile salts, and taurocholate binding sites in rat liver.
    Biochemistry. 1984 Dec 18;23(26):6459-66 PMID: 6529562
  33. Primary cultures of rat hepatocytes as a model system of canalicular development, biliary secretion, and intrahepatic cholestasis. I. Distribution of filipin-cholesterol complexes during de novo formation of bile canaliculi.
    Eur J Cell Biol. 1982 Nov;29(1):68-76 PMID: 7151827
  34. The mechanism of biliary excretion of alpha 1-acid glycoprotein in the rat: evidence for a molecular weight-dependent, nonreceptor-mediated pathway.
    Hepatology. 1982 Nov-Dec;2(6):800-3 PMID: 7141391
  35. Distribution of secretory component in hepatocytes and its mode of transfer into bile.
    Biochem J. 1980 Sep 15;190(3):819-26 PMID: 7470082
  36. Functional implications of liver cell heterogeneity.
    Gastroenterology. 1981 Feb;80(2):393-403 PMID: 7004997
  37. Relatively high biliary secretory maximum for non-micelle-forming bile acid: possible significance for mechanism of secretion.
    Q J Exp Physiol. 1986 Jul;71(3):475-82 PMID: 3763809
  38. Subfractionation of hepatic endosomes in Nycodenz gradients and by free-flow electrophoresis. Separation of ligand-transporting and receptor-enriched membranes.
    Biochem J. 1985 Nov 15;232(1):25-32 PMID: 2867760
  39. Sources of the proteins of rat bile.
    Biochim Biophys Acta. 1978 Nov 1;543(4):497-507 PMID: 718986
  40. Liver cell membrane solubilization may control maximum secretory rate of cholic acid in the rat.
    Am J Physiol. 1987 Jan;252(1 Pt 1):G84-91 PMID: 3812691
  41. In vitro effect of free bile acids on the bile canalicular membrane phospholipids in the rat.
    Can J Biochem. 1976 Dec;54(12):1040-6 PMID: 189882
  42. Effect of organic anions on biliary lipids in the rat.
    Gastroenterology. 1982 Nov;83(5):1120-6 PMID: 7117794
  43. Cholesterol-phospholipid vesicles in human bile: an ultrastructural study.
    Biochim Biophys Acta. 1986 Oct 24;879(1):14-21 PMID: 3768382
  44. Membrane fluidity and bile salt damage.
    Biochim Biophys Acta. 1981 Jan 8;640(1):55-65 PMID: 7213693
  45. Acute effects of pentobarbital-anaesthesia on bile secretion.
    Biochem Pharmacol. 1985 May 15;34(10):1731-6 PMID: 4004889
  46. Alterations in hepatic pericanalicular cytoplasm during enhanced bile secretory activity.
    Lab Invest. 1979 Apr;40(4):512-7 PMID: 431048
  47. The liver: an integral part of the enteric mucosal immune system.
    Hepatology. 1982 May-Jun;2(3):379-84 PMID: 7042507
  48. Hepatic extraction of bile acids in rats.
    Biochem Pharmacol. 1982 Jan 15;31(2):205-9 PMID: 7059362
  49. Sources of proteins in human bile.
    Gut. 1985 May;26(5):500-9 PMID: 3996941
  50. Membrane lipid composition and susceptibility to bile salt damage.
    Biochim Biophys Acta. 1980 Jun 20;599(1):294-300 PMID: 7397151
  51. Rat liver canalicular membrane vesicles. Isolation and topological characterization.
    J Biol Chem. 1983 Apr 25;258(8):5183-8 PMID: 6833295
  52. Micellar theory of biliary cholesterol excretion.
    Am J Physiol. 1972 Jan;222(1):61-7 PMID: 5060227
  53. 1-Naphthylisothiocyanate-induced permeability of hepatic tight junctions to proteins.
    Biochem J. 1986 Sep 1;238(2):323-8 PMID: 3800941
  54. Uptake of bile acids by perfused rat liver.
    Am J Physiol. 1976 Sep;231(3):734-42 PMID: 788526
  55. Effects of bile salts of human erythrocytes. Plasma membrane vesiculation, phospholipid solubilization and their possible relationships to bile secretion.
    Biochim Biophys Acta. 1978 May 4;509(1):33-47 PMID: 647007
  56. Bile acid transport in cultured rat hepatocytes.
    Am J Physiol. 1982 Dec;243(6):G484-92 PMID: 7149031
  57. Primary hepatocytes in monolayer culture: a model for studies on lipoprotein metabolism.
    Annu Rev Physiol. 1984;46:403-15 PMID: 6370114
  58. The effects of colchicine and vinblastine on the biliary excretion of carcinoembryonic antigen.
    Hepatology. 1985 Mar-Apr;5(2):207-10 PMID: 3979951
  59. The influence of conjugation of cholic acid on its uptake and secretion: hepatic extraction of taurocholate and cholate in the dog.
    J Physiol. 1967 Apr;189(2):337-50 PMID: 6034118
  60. Debits and credits: a current account of cholesterol gall stone disease.
    Gut. 1984 Oct;25(10):1021-8 PMID: 6383962
  61. Newly identified bile acid binders in rat liver cytosol. Purification and comparison with glutathione S-transferases.
    J Biol Chem. 1983 Mar 25;258(6):3602-7 PMID: 6833218
  62. Mechanisms of cholestasis.
    Lab Invest. 1986 Jun;54(6):593-608 PMID: 2423777
  63. Studies on bile acids. Some observations on the intracellular localization of major bile acids in rat liver.
    Biochemistry. 1966 Nov;5(11):3662-8 PMID: 5972346
  64. Biliary proteins. Unique inhibitors of cholesterol crystal nucleation in human gallbladder bile.
    J Clin Invest. 1984 Jan;73(1):35-45 PMID: 6690482
  65. Bile secretory apparatus: evidence for a vesicular transport mechanism for proteins in the rat, using horseradish peroxidase and [125I]insulin.
    Gastroenterology. 1980 Jun;78(6):1373-88 PMID: 6989703
  66. Origin and nature of the proteins of bile. II. A comparative analysis of serum, hepatic lymph and bile proteins in the dog.
    Eur J Clin Invest. 1974 Aug;4(4):241-6 PMID: 4421260
  67. The lipid composition of plasma membrane subfractions originating from the three major functional domains of the rat hepatocyte cell surface.
    Biochim Biophys Acta. 1976 Dec 14;455(3):655-64 PMID: 999933
  68. The composition and polymeric structure of mucus glycoprotein from human gallbladder bile.
    Biochim Biophys Acta. 1982 Sep 7;706(2):221-8 PMID: 7126600
  69. Biochemistry of gallstone formation.
    Clin Gastroenterol. 1983 Jan;12(1):25-48 PMID: 6347457
  70. Effects of bile salts on the plasma membranes of isolated rat hepatocytes.
    Biochem J. 1980 May 15;188(2):321-7 PMID: 7396866
  71. Mechanisms of bile formation, hepatic uptake, and biliary excretion.
    Pharmacol Rev. 1984 Mar;36(1):1-67 PMID: 6144113
  72. Hepatocellular uptake of organic anions.
    Prog Liver Dis. 1986;8:125-44 PMID: 3520658
  73. Structural and functional polarity of canalicular and basolateral plasma membrane vesicles isolated in high yield from rat liver.
    J Cell Biol. 1984 Mar;98(3):991-1000 PMID: 6699096
  74. Sublobular compartmentation of pharmacologic events (SCOPE): metabolic fluxes in periportal and pericentral regions of the liver lobule.
    Hepatology. 1985 Jan-Feb;5(1):144-51 PMID: 3967857
  75. Hepatic handling of bile salts and protein in the rat during intrahepatic cholestasis.
    Gastroenterology. 1983 May;84(5 Pt 1):978-86 PMID: 6832571
  76. Taurocholate transport by rat liver canalicular membrane vesicles. Evidence for the presence of an Na+-independent transport system.
    J Clin Invest. 1984 Mar;73(3):659-63 PMID: 6707198
  77. The architecture of bile secretion. A morphological perspective of physiology.
    Dig Dis Sci. 1980 Aug;25(8):609-29 PMID: 6995048
  78. Enzymes and proteins in bile. Variations in output in rat cannula bile during and after depletion of the bile-salt pool.
    Biochem J. 1981 Apr 15;196(1):11-6 PMID: 7306064
  79. Bile secretion and liver cell heterogeneity in the rat.
    J Lab Clin Med. 1978 Feb;91(2):350-62 PMID: 621433
  80. The liver in the IgA secretory immune system. Dogs, but not rats and rabbits, are suitable models for human studies.
    Hepatology. 1983 Nov-Dec;3(6):980-8 PMID: 6354905
  81. Bile-salt-binding polypeptides in plasma membranes of hepatocytes revealed by photoaffinity labelling.
    Eur J Biochem. 1982 Dec;129(1):13-24 PMID: 7160376
  82. Uptake and intracellular disposition of plasma-derived proteins and apoproteins by hepatocytes.
    Prog Liver Dis. 1982;7:51-69 PMID: 7051156
  83. Nature and origin of the proteins of bile. I. A comparative analysis of serum and bile proteins in man.
    Eur J Clin Invest. 1974 Aug;4(4):235-9 PMID: 4423686
  84. Changing concepts of cholesterol solubility in bile.
    Gastroenterology. 1986 Sep;91(3):772-5 PMID: 3732773
  85. Excretory function of the liver.
    Int Rev Physiol. 1980;21:103-50 PMID: 6993393
  86. Hepatic bile formation (first of two parts).
    N Engl J Med. 1976 Dec 23;295(26):1464-9 PMID: 792689
  87. Direct determination of the driving forces for taurocholate uptake into rat liver plasma membrane vesicles.
    J Clin Invest. 1983 Oct;72(4):1470-81 PMID: 6630516
  88. Transcytosis and paracellular movements of horseradish peroxidase across liver parenchymal tissue from blood to bile. Effects of alpha-naphthylisothiocyanate and colchicine.
    Biochem J. 1985 Jul 15;229(2):529-37 PMID: 4038279
  89. LECITHIN FATTY ACID COMPOSITION IN BILE AND PLASMA OF MAN, DOGS, RATS, AND OXEN.
    J Lipid Res. 1965 Jan;6:96-9 PMID: 14280480
  90. Hepatocyte bile secretion: current views and controversies.
    Hepatology. 1981 Jul-Aug;1(4):352-9 PMID: 6269984
  91. Rapid kinetic analysis of the bile-salt-dependent secretion of phospholipid, cholesterol and a plasma-membrane enzyme into bile.
    Biochem J. 1984 Sep 15;222(3):631-7 PMID: 6091620
  92. Ampicillin inhibits biliary cholesterol secretion.
    Dig Dis Sci. 1985 Mar;30(3):253-6 PMID: 3971836
  93. Purification of bile acid-binding proteins from rat hepatic cytosol. Use of a photoaffinity label to detect novel Y' binders.
    Biochim Biophys Acta. 1986 Feb 12;875(2):270-85 PMID: 3942766
  94. Cholic acid binding to isolated rat liver plasma membranes.
    Hoppe Seylers Z Physiol Chem. 1977 May;358(5):543-53 PMID: 881162
  95. Bile as a source of potential reactive metabolites.
    Toxicology. 1982;25(2-3):99-111 PMID: 6760466
  96. Hepatocyte handling of immunoglobulin A in the rat: the role of microtubules.
    Gastroenterology. 1983 Jul;85(1):130-40 PMID: 6343176
  97. Effect of taurochenodeoxycholate or tauroursodeoxycholate upon biliary output of phospholipids and plasma-membrane enzymes, and the extent of cell damage, in isolated perfused rat livers.
    Biochem J. 1983 Oct 15;216(1):107-11 PMID: 6316931
  98. Autoradiographic evidence for hepatic lobular concentration gradient of bile acid derivative.
    Am J Physiol. 1980 Mar;238(3):G233-7 PMID: 7369371
  99. Nature of bile acid maximum secretory rate in the rat.
    Am J Physiol. 1981 Oct;241(4):G337-43 PMID: 7315971
  100. Mechanisms of secretion of proteins into bile: studies in the perfused rat liver.
    Hepatology. 1986 Jul-Aug;6(4):587-94 PMID: 3525367
  101. Biliary excretion of lecithin and cholesterol in the dog.
    J Clin Invest. 1972 Jun;51(6):1337-50 PMID: 5024035
  102. Contractility of bile canaliculi: implications for liver function.
    Science. 1981 May 29;212(4498):1041-2 PMID: 7015506
  103. Vesicle-mediated transfer of phospholipids to plasma membrane during cell aggregation of Dictyostelium discoideum.
    J Biol Chem. 1981 Jun 10;256(11):5845-50 PMID: 7240176
  104. Role of membranes in bile formation. Comparison of the composition of bile and a liver bile-canalicular plasma-membrane subfraction.
    Biochem J. 1976 Mar 15;154(3):589-95 PMID: 182122
  105. Physicochemical properties of bile acids and their relationship to biological properties: an overview of the problem.
    J Lipid Res. 1984 Dec 15;25(13):1477-89 PMID: 6397555
  106. Mechanisms of hepatic bile formation.
    Annu Rev Physiol. 1977;39:323-47 PMID: 192137
  107. Control of biliary phospholipid secretion. Effect of continuous and discontinuous infusion of taurocholate on biliary phospholipid secretion.
    Biochem J. 1986 Mar 1;234(2):421-7 PMID: 3718477
  108. Culturing hepatocytes and other differentiated cells.
    Hepatology. 1984 May-Jun;4(3):548-59 PMID: 6373552
  109. Movement of endocytic shuttle vesicles from the sinusoidal to the bile canalicular face of hepatocytes does not depend on occupation of receptor sites.
    FEBS Lett. 1980 May 5;113(2):201-5 PMID: 6248358
  110. A non-micellar mode of cholesterol transport in human bile.
    FEBS Lett. 1983 Jun 13;156(2):265-8 PMID: 6852259
  111. Identification and quantitation of cholanoic acids in hepatic and extra-hepatic tissues of rat.
    Lipids. 1975 Jun;10(6):340-7 PMID: 1134222
  112. Bile acid-dependent secretion of alkaline phosphatase in rat bile.
    Hepatology. 1982 Jul-Aug;2(4):433-9 PMID: 7095744
  113. Hepatic bile acid transport: effect of conjugation and position of hydroxyl groups.
    Am J Physiol. 1975 Aug;229(2):298-302 PMID: 1163658
  114. Contribution of vesicular and micellar carriers to cholesterol transport in human bile.
    J Lipid Res. 1985 Jun;26(6):699-704 PMID: 4031648
  115. Biliary protein output by isolated perfused rat livers. Effects of bile salts.
    Biochem J. 1983 Feb 15;210(2):549-57 PMID: 6305344
  116. Intracellular transport of cholesterol to the plasma membrane.
    J Biol Chem. 1982 Dec 10;257(23):14256-62 PMID: 6815192
  117. The lipid fluidity of rat liver membrane subfractions.
    Biochem J. 1983 Sep 15;214(3):851-4 PMID: 16743791
  118. Ultrastructural events in the translocation of polymeric IgA by rat hepatocytes.
    J Immunol. 1982 Mar;128(3):1181-7 PMID: 7057034
  119. Cell membrane potential and resistance in liver.
    J Physiol. 1978 Nov;284:105-26 PMID: 731453
  120. Secretory component: the polymeric immunoglobulin receptor. What's in it for the gastroenterologist and hepatologist?
    Gastroenterology. 1985 Sep;89(3):667-82 PMID: 3926595
  121. Tight junctions in normal and cholestatic liver: does the paracellular pathway have functional significance?
    Hepatology. 1983 Jul-Aug;3(4):614-7 PMID: 6345333
  122. Intracellular and transcellular transport of secretory component and albumin in rat hepatocytes.
    J Cell Biol. 1983 Nov;97(5 Pt 1):1582-91 PMID: 6630294
  123. Effect of primary bile acids on bile lipid secretion from perfused dog liver.
    Am J Physiol. 1975 Sep;229(3):714-20 PMID: 1211466
  124. Fluorescence anisotropy from diphenylhexatriene in rat liver plasma membranes.
    Biochim Biophys Acta. 1982 Jul 28;689(2):403-9 PMID: 7115717
  125. Increased tight junction permeability: a possible mechanism of oestrogen cholestasis.
    Eur J Clin Invest. 1983 Oct;13(5):383-90 PMID: 6416852
  126. Effect of colchicine on the transfer of IgA across hepatocytes into bile in isolated perfused rat livers.
    FEBS Lett. 1980 Nov 3;120(2):278-82 PMID: 7439402
  127. Factors affecting cholesterol monohydrate crystal nucleation time in model systems of supersaturated bile.
    J Lipid Res. 1985 Sep;26(9):1102-11 PMID: 4067431
  128. Lipid fluidity of hepatocyte plasma membrane subfractions and their differential regulation by calcium.
    Biochim Biophys Acta. 1983 Jan 5;727(1):209-12 PMID: 6824651
  129. Mechanisms and consequences of ion transport in the liver.
    Prog Liver Dis. 1986;8:145-59 PMID: 3012635
  130. Phospholipid, cholesterol, polypeptide and glycoprotein composition of hepatic endosome subfractions.
    Biochem J. 1985 Nov 15;232(1):33-6 PMID: 2867761
  131. Cellular mechanisms of bile formation.
    Gastroenterology. 1982 Feb;82(2):346-57 PMID: 6274732
  132. Development of intrahepatic cholestasis by alpha-naphthylisothiocyanate in rats.
    Gastroenterology. 1982 Mar;82(3):507-14 PMID: 7054045
Article Info
Journal
The Biochemical journal
Abbr.
Biochem J
ISSN
0264-6021
Published
1987-06-01
Pages
249-61
Language
English
Region
England
NLM ID
2984726R
PMCID
PMC1147985
Subset
IM
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]