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PMID: 342909 Published · ppublish English Journal Article

[Correlation between a novel phenotype towards streptomycin and the binding of an additional protein to the ribosome in mutants of Escherichia coli B].

Molecular & general genetics : MGG ·Vol. 158 ·No. 1 ·1977-12-14 ·Pages 55-61

Dabbs ER

Abstract

Mutants of Escherichia coli have been isolated containing streptomycin suppressors that exhibit novel phenotypes with respect to strA alleles. In one class of these mutants, the suppressor effect parallels a strong binding to the ribosome of an additional protein in at least stoichiometric amounts. Transduction experiments confirmed that the level of suppression and the degree of binding of this protein were correlated.

MeSH Terms
Bacterial Proteins/genetics,metabolism Drug Resistance, Microbial Escherichia coli/genetics Mutation Phenotype Ribosomal Proteins/genetics,metabolism Streptomycin/pharmacology Suppression, Genetic Transduction, Genetic
Chemicals
Bacterial Proteins Ribosomal Proteins Streptomycin
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Dabbs E R
References (18)
18 references, click to expand
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Article Info
Journal
Molecular & general genetics : MGG
Abbr.
Mol Gen Genet
ISSN
0026-8925
DOI
10.1007/BF00455119
Published
1977-12-14
Pages
55-61
Language
English
Region
Germany
NLM ID
0125036
Subset
IM
External Links
PubMed source DOI: 10.1007/BF00455119
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