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PMID: 3460333 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Localization of the gene encoding human erythroid-potentiating activity to chromosome region Xp11.1----Xp11.4.

American journal of human genetics ·Vol. 38 ·No. 6 ·1986-06-00 ·Pages 819-26

Huebner K, Isobe M, Gasson JC, Golde DW, Croce CM

Abstract

We have localized the human gene for erythroid potentiating activity (EPA) to the X chromosome by analysis of its segregation pattern in mouse-human somatic cell hybrids. The EPA gene has been further localized to human chromosome region Xp11.1----Xp11.4 by in situ hybridization of a molecularly cloned EPA genomic fragment to metaphase chromosomes.

MeSH Terms
Animals Chromosome Mapping DNA/genetics Genetic Markers Glycoproteins/genetics Humans Hybrid Cells Karyotyping Lymphokines/genetics Mice Nucleic Acid Hybridization Tissue Inhibitor of Metalloproteinases X Chromosome
Chemicals
Genetic Markers Glycoproteins Lymphokines Tissue Inhibitor of Metalloproteinases DNA
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Huebner K
Isobe M
Gasson J C
Golde D W
Croce C M
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23 references, click to expand
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Article Info
Journal
American journal of human genetics
Abbr.
Am J Hum Genet
ISSN
0002-9297
Published
1986-06-00
Pages
819-26
Language
English
Region
United States
NLM ID
0370475
PMCID
PMC1684855
Subset
IM
Grants
NCI NIH HHS · CA-10805 · United States
NCI NIH HHS · CA-16685 · United States
NCI NIH HHS · CA-21124 · United States
External Links
PubMed source PMC Full Text View journal details
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