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PMID: 3521489 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Plasmid-mediated high-level resistance to erythromycin in Escherichia coli.

Antimicrobial agents and chemotherapy ·Vol. 29 ·No. 3 ·1986-03-00 ·Pages 515-8

Andremont A, Gerbaud G, Courvalin P

Abstract

Escherichia coli BM2195 was found to be resistant to high levels of erythromycin. This new resistance phenotype was due to the constitutive synthesis of an erythromycin esterase which inactivates the antibiotic. The gene conferring resistance to erythromycin in this strain is carried on a 61-kilobase self-transferable plasmid, pIP1100, belonging to incompatibility group X.

MeSH Terms
Drug Resistance, Microbial Erythromycin/pharmacology Escherichia coli/drug effects,genetics Genes, Bacterial Kinetics Plasmids
Chemicals
Erythromycin
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Andremont A
Gerbaud G
Courvalin P
References (23)
23 references, click to expand
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Article Info
Journal
Antimicrobial agents and chemotherapy
Abbr.
Antimicrob Agents Chemother
ISSN
0066-4804
DOI
10.1128/AAC.29.3.515
Published
1986-03-00
Pages
515-8
Language
English
Region
United States
NLM ID
0315061
PMCID
PMC180425
Subset
IM
External Links
PubMed source DOI: 10.1128/AAC.29.3.515 PMC Full Text View journal details
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