Genetic analysis of a mouse t complex locus that is homologous to a kidney cDNA clone.
A mouse kidney cDNA clone, pMK174, identifies restriction fragment length polymorphisms (RFLPs) that map to two unlinked loci. One, designated D17Rp17, has been mapped near quaking, (qk), on chromosome 17 using three sets of recombinant inbred (RI) strains. A study of several t haplotypes resulted in the identification of t-specific alleles of D17Rp17 that map to the proximal half of the t complex. Neither t-specific nor wild-type D17Rp17 alleles are present in chromosomes carrying either the T Orleans (TtOrl) or the T hairpin tail (Thp) deletions. Comparison with other molecular markers indicates that pMK174 identifies a new proximal t complex locus, Rp17. The second locus identified by pMK174, termed D4Rp18, is tentatively assigned to chromosome 4 by mouse-Chinese hamster somatic cell hybrid analysis.
15 references, click to expand
-
Genes for immunoglobulin heavy chain and serum prealbumin protein are linked in mouse.Nature. 1975 Aug 21;256(5519):644-6 PMID: 807855
-
Genetic analysis of the proximal portion of the mouse t complex: evidence for a second inversion within t haplotypes.Cell. 1986 Feb 14;44(3):469-76 PMID: 3455895
-
Dispersion of alpha-like globin genes of the mouse to three different chromosomes.Nature. 1981 Sep 17-23;293(5829):196-200 PMID: 6168916
-
Genetic control of cross-reactive cytotoxic T-lymphocyte responses to a BALB/c tumor.Immunogenetics. 1981;14(3-4):263-72 PMID: 6800944
-
Gene mapping within the T/t complex of the mouse. II. Anomalous position of the H-2 complex in t haplotypes.Cell. 1982 Mar;28(3):471-6 PMID: 7074683
-
DNA sequence polymorphism in an androgen-regulated gene is associated with alteration in the encoded RNAs.Proc Natl Acad Sci U S A. 1983 Jan;80(2):501-4 PMID: 6188152
-
Molecular clones of the mouse t complex derived from microdissected metaphase chromosomes.Cell. 1984 Mar;36(3):783-8 PMID: 6697397
-
The alpha-globin pseudogene on mouse chromosome 17 is closely linked to H-2.J Exp Med. 1984 Mar 1;159(3):958-63 PMID: 6321630
-
Evolution and variation of renin genes in mice.Genetics. 1984 Nov;108(3):651-67 PMID: 6389258
-
Molecular probes define different regions of the mouse t complex.Cell. 1985 Jan;40(1):63-9 PMID: 2981632
-
Linkage of genes for laminin B1 and B2 subunits on chromosome 1 in mouse.In Vitro Cell Dev Biol. 1985 Aug;21(8):477-84 PMID: 2993224
-
Mouse t haplotypes.Annu Rev Genet. 1985;19:179-208 PMID: 3909941
-
Male sterility of the mouse t-complex is due to homozygosity of the distorter genes.Cell. 1986 Jan 31;44(2):357-63 PMID: 3943128
-
Nonhomologous pairing in mice heterozygous for a t haplotype can produce recombinant chromosomes with duplications and deletions.Genetics. 1986 Jul;113(3):723-34 PMID: 3732789
-
Detection of specific sequences among DNA fragments separated by gel electrophoresis.J Mol Biol. 1975 Nov 5;98(3):503-17 PMID: 1195397
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