Home LiteratureArticle Details
PMID: 3827358 Published · ppublish English Journal Article

Subtotal resection of the head of the pancreas combined with ductal obliteration of the distal pancreas in chronic pancreatitis.

Annals of surgery ·Vol. 205 ·No. 3 ·1987-03-00 ·Pages 240-5

Kerremans RP, Penninckx FM, De Groote J, Fevery J

Abstract

Subtotal resection of the head of the pancreas combined with duct obliteration of the distal pancreas by prolamine was performed in 12 selected patients who had chronic alcohol-induced pancreatitis with most destruction in the proximal pancreas. The main indication for operation was intractable pain. There was no postoperative mortality but morbidity was high when no pancreaticojejunostomy was constructed. After a follow-up period of 32 months, lasting pain relief was obtained in 10 patients; pseudocyst formation occurred in three patients; calcification of the distal pancreas, absent before operation, was demonstrated in four of six patients; six of 11 nondiabetic patients became hyperglycemic either abruptly (1 patient) or progressively (5 patients); quality of life improved in most patients. This procedure preserves the stomach, duodenum, spleen, distal pancreas and common bile duct if possible. However, pancreatic ductal obliteration with prolamine does not prevent relapses of chronic pancreatitis.

MeSH Terms
Adult Calcinosis/etiology Chronic Disease Diabetes Mellitus, Type 1/etiology Diatrizoate Drug Combinations Fatty Acids Follow-Up Studies Humans Hyperglycemia/etiology Male Middle Aged Pancreatectomy/adverse effects,methods,mortality Pancreatic Ducts Pancreatic Pseudocyst/etiology Pancreatitis/pathology,physiopathology,surgery Propylene Glycols Proteins/therapeutic use Quality of Life Zein
Chemicals
Drug Combinations Fatty Acids Propylene Glycols Proteins Diatrizoate Zein alcoholic prolamine solution
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Kerremans R P
Penninckx F M
De Groote J
Fevery J
References (51)
51 references, click to expand
  1. Obstruction of the pancreatic duct by ligature in the treatment of pancreatitis.
    Ann Surg. 1967 Jan;165(1):56-60 PMID: 6018297
  2. The effect of duct obliteration on the histology and endocrine function of the canine pancreas.
    Transplantation. 1984 Jul;38(1):13-7 PMID: 6377605
  3. Long term follow-up study of fifty patients with pancreaticojejunostomy.
    Surg Gynecol Obstet. 1973 Mar;136(3):353-8 PMID: 4688800
  4. Chronic alcoholic pancreatitis. Treatment by ductal obstruction.
    Am J Surg. 1973 May;125(5):538-41 PMID: 4699197
  5. Current status of pancreatojejunostomy in the management of chronic pancreatitis.
    Am J Surg. 1977 Jan;133(1):46-51 PMID: 319695
  6. Pancreatectomy for chronic pancreatitis.
    Ann Surg. 1976 Oct;184(4):403-13 PMID: 1015887
  7. [Blocking of pancreatic exocrine function in the treatment of chronic pancreatitis (author's transl)].
    Dtsch Med Wochenschr. 1977 Mar 18;102(11):392-5 PMID: 321199
  8. Pancreatic autotransplantation following resection.
    Surgery. 1978 Mar;83(3):359-60 PMID: 343288
  9. Preservation of the pylorus in pancreaticoduodenectomy.
    Surg Gynecol Obstet. 1978 Jun;146(6):959-62 PMID: 653575
  10. [Occlusion of pancreatic duct system by injection of a fast-solidifying amino acid solution (author's transl)].
    Langenbecks Arch Chir. 1978 Oct 16;346(3):149-66 PMID: 732402
  11. Pain relief by surgery in chronic pancreatitis? Relationship between pain relief, pancreatic dysfunction, and alcohol withdrawal.
    Scand J Gastroenterol. 1979;14(2):209-15 PMID: 86198
  12. [A new concept in the surgery of chronic pancreatitis (author's transl)].
    Dtsch Med Wochenschr. 1979 Jul 13;104(28):1003-6 PMID: 456273
  13. Pancreatic duct ligation in the therapy of chronic pancreatitis.
    Am Surg. 1979 Jul;45(7):449-52 PMID: 380423
  14. [Comparative study of 117 cases of total or subtotal duodeno-pancreatectomies for chronic pancreatitis. First results from sclerosis of the pancreatic tail during operation (author's transl)].
    Chirurgie. 1979;105(3):187-92 PMID: 467155
  15. Duct obstruction with an acrylate glue for treatment of chronic alcoholic pancreatitis.
    Lancet. 1979 Sep 15;2(8142):557-9 PMID: 89560
  16. Surgical treatment of chronic pancreatitis. Twenty-two years' experience.
    Ann Surg. 1979 Sep;190(3):312-9 PMID: 485605
  17. Long-term patency, pancreatic function, and pain relief after lateral pancreaticojejunostomy for chronic pancreatitis.
    Gastroenterology. 1980 Aug;79(2):289-93 PMID: 7399232
  18. [Experiences with duodenum-sparing pancreas head resection in chronic pancreatitis].
    Chirurg. 1980 May;51(5):303-7 PMID: 7408575
  19. Ductal drainage or resection for chronic pancreatitis.
    Am J Surg. 1981 Jan;141(1):28-33 PMID: 7457724
  20. Distal pancreatectomy and islet autotransplantation for chronic pancreatitis.
    Ann Surg. 1981 Mar;193(3):312-7 PMID: 6782958
  21. Segmental pancreas autotransplantation in man following total or near total pancreatectomy for serious recurrent chronic pancreatitis.
    Transplant Proc. 1980 Dec;12(4 Suppl 2):15-8 PMID: 6784304
  22. Follow-up study of chronic pancreatitis.
    Gastroenterol Jpn. 1981;16(1):46-53 PMID: 7227758
  23. Results of partial and total pancreaticoduodenectomy in 117 patients with chronic pancreatitis.
    World J Surg. 1981 Mar;5(2):269-75 PMID: 7245796
  24. Liver histopathology in chronic common bile duct stenosis due to chronic alcoholic pancreatitis.
    Hepatology. 1981 Jan-Feb;1(1):65-72 PMID: 7286890
  25. Segmental pancreatic autotransplantation for chronic pancreatitis.
    Am J Surg. 1983 Apr;145(4):437-42 PMID: 6340550
  26. [Current trends in the surgical treatment of chronic pancreatitis].
    Acta Chir Belg. 1983 Jan-Feb;83(1):60-4 PMID: 6858530
  27. Evolution of pain in chronic relapsing pancreatitis: a study of operated and nonoperated patients.
    Am J Gastroenterol. 1983 Aug;78(8):495-501 PMID: 6192709
  28. Common bile duct strictures associated with chronic pancreatitis.
    Am Surg. 1983 Jul;49(7):350-8 PMID: 6614652
  29. Chronic pancreatitis: long-term surgical results of pancreatic duct drainage, pancreatic resection, and near-total pancreatectomy and islet autotransplantation.
    Surgery. 1984 Oct;96(4):608-16 PMID: 6435270
  30. [Experiences with pancreas occlusion following cephalic duodenopancreatectomy].
    Zentralbl Chir. 1984;109(17):1112-21 PMID: 6495915
  31. Surgical treatment of chronic pancreatitis.
    Am J Surg. 1984 Dec;148(6):754-9 PMID: 6507746
  32. [Endoscopic occlusion treatment in patients with chronic pancreatitis].
    Chirurg. 1985 Jan;56(1):36-40 PMID: 3971787
  33. Duodenum-preserving resection of the head of the pancreas in patients with severe chronic pancreatitis.
    Surgery. 1985 Apr;97(4):467-73 PMID: 3983823
  34. Conservation of pancreatic tissue by combined gastric, biliary, and pancreatic duct drainage for pain from chronic pancreatitis.
    Am J Surg. 1985 Apr;149(4):563-9 PMID: 2580454
  35. Pancreatic function after endoscopic and surgical occlusion of the pancreatic duct in patients with chronic pancreatitis.
    Endoscopy. 1985 Mar;17(2):60-3 PMID: 3886372
  36. [Therapeutic pancreatic duct occlusion in chronic pancreatitis: clinical, exocrine and endocrine consequences in a 12 month follow-up study].
    Langenbecks Arch Chir. 1985;363(3):149-63 PMID: 3887075
  37. Pyloric preservation with the Whipple procedure.
    Surg Clin North Am. 1985 Apr;65(2):263-71 PMID: 4012528
  38. Evaluation of the surgical treatment of chronic calcifying pancreatitis.
    Surg Gynecol Obstet. 1985 Aug;161(2):117-28 PMID: 4023892
  39. The effects of duct obliteration and of autotransplantation on the endocrine function of canine pancreatic segments.
    Diabetes. 1985 Oct;34(10):1008-13 PMID: 3899803
  40. Pancreatogastrostomy: an ideal complement to pancreatic head resection with preservation of the pylorus in the treatment of chronic pancreatitis.
    Am J Surg. 1985 Nov;150(5):608-11 PMID: 4061742
  41. [Surgical drainage in the treatment of chronic pancreatitis. Apropos of 81 cases].
    Chirurgie. 1985;111(4):371-7 PMID: 4064829
  42. Redrainage of the pancreatic duct in chronic pancreatitis.
    Am J Surg. 1986 Jan;151(1):150-6 PMID: 2418698
  43. Parapancreatic biliary and intestinal obstruction in chronic obstructive pancreatitis. Is prophylactic bypass necessary?
    Am J Surg. 1986 Feb;151(2):256-8 PMID: 3946760
  44. Subtotal pancreatic head resection combined with left pancreatic duct obstruction in chronic pancreatitis.
    Acta Gastroenterol Belg. 1985 Nov-Dec;48(6):603-6 PMID: 3837585
  45. Experience with ligation of the pancreatic ducts in the treatment of chronic relapsing pancreatitis.
    Am J Surg. 1955 Aug;90(2):266-80 PMID: 13238681
  46. The role of surgery for chronic pancreatitis and its complications.
    Surg Annu. 1983;15:283-305 PMID: 6623318
  47. Coeliac plexus block for pain in pancreatic cancer and chronic pancreatitis.
    Br J Surg. 1983 Dec;70(12):730-2 PMID: 6640255
  48. Course and outcome of chronic pancreatitis. Longitudinal study of a mixed medical-surgical series of 245 patients.
    Gastroenterology. 1984 May;86(5 Pt 1):820-8 PMID: 6706066
  49. Pancreas and islet transplant registry data.
    World J Surg. 1984 Apr;8(2):270-5 PMID: 6428064
  50. [Chronic alcoholic pancreatitis: relation of pain to withdrawal and pancreatic surgery].
    Gastroenterol Clin Biol. 1984 May;8(5):419-25 PMID: 6735054
  51. Late effect of pancreatic duct ligation on beta cell function.
    Am J Surg. 1969 Jan;117(1):33-9 PMID: 4882420
Article Info
Journal
Annals of surgery
Abbr.
Ann Surg
ISSN
0003-4932
DOI
10.1097/00000658-198703000-00004
Published
1987-03-00
Pages
240-5
Language
English
Region
United States
NLM ID
0372354
PMCID
PMC1492707
Subset
IM
External Links
PubMed source DOI: 10.1097/00000658-198703000-00004 PMC Full Text View journal details
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2