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PMID: 3897794 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

REV7, a new gene concerned with UV mutagenesis in yeast.

Molecular & general genetics : MGG ·Vol. 200 ·No. 1 ·1985-00-00 ·Pages 80-5

Lawrence CW, Das G, Christensen RB

Abstract

Three allelic mutations of a new yeast gene, which we have named REV7, have been isolated by testing 313 methyl methane sulfonate sensitive mutants for UV-induced reversion of a lys2 allele. Rev7 mutants are markedly deficient with respect to UV-induced reversion of lys2, are slightly sensitive to UV and appear to be in the RAD6 epistasis group for UV survival. Rev7-1, which is probably an amber mutation, does not appear to affect sporulation in homozygous diploids. The REV7 gene is located about 12 cM distal to HIS5 on chromosome IX.

MeSH Terms
Chromosome Mapping Crosses, Genetic Dose-Response Relationship, Radiation Genes, Fungal Genetic Complementation Test Kinetics Methyl Methanesulfonate/pharmacology Mutation Phenotype Recombination, Genetic Saccharomyces cerevisiae/drug effects,genetics,radiation effects Ultraviolet Rays
Chemicals
Methyl Methanesulfonate
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Lawrence C W
Das G
Christensen R B
References (17)
17 references, click to expand
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Article Info
Journal
Molecular & general genetics : MGG
Abbr.
Mol Gen Genet
ISSN
0026-8925
DOI
10.1007/BF00383316
Published
1985-00-00
Pages
80-5
Language
English
Region
Germany
NLM ID
0125036
Subset
IM
Grants
NIGMS NIH HHS · GM21858 · United States
External Links
PubMed source DOI: 10.1007/BF00383316
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