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PMID: 3911021 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

A new dispensable genetic locus of the terminus region involved in control of cell division in Escherichia coli.

Molecular & general genetics : MGG ·Vol. 201 ·No. 2 ·1985-00-00 ·Pages 146-50

Béjar S, Bouché JP

Abstract

Temperature-sensitive mutants defective in cell division were isolated after localised mutagenesis of the terminus region of the Escherichia coli chromosome. The defective gene in one of these mutants, dicA, was mapped at 34.9 min by linkage with manA and with three physically characterized Tn10 insertions. Temperature-sensitivity conferred by mutation dicA1 in a recA background [corrected] was suppressed by the presence of hybrid plasmids carrying the wild-type gene. In addition, the mutation was suppressed either by tranposon inactivation of a nearby gene, dicB, or by deletion of the entire dicA-dicB interval. These results define the dicA-dicB locus as a new dispensable genetic cluster involved in the control of cell division.

MeSH Terms
Escherichia coli/genetics,growth & development Genes, Bacterial Genetic Vectors Genotype Mutation Plasmids
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Béjar S
Bouché J P
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24 references, click to expand
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Article Info
Journal
Molecular & general genetics : MGG
Abbr.
Mol Gen Genet
ISSN
0026-8925
DOI
10.1007/BF00425651
Published
1985-00-00
Pages
146-50
Language
English
Region
Germany
NLM ID
0125036
Subset
IM
External Links
PubMed source DOI: 10.1007/BF00425651
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