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PMID: 39495 Published · ppublish English Comparative Study Journal Article Research Support, U.S. Gov't, P.H.S.

Survival of coxsackievirus B3 under diverse environmental conditions.

Applied and environmental microbiology ·Vol. 37 ·No. 5 ·1979-05-00 ·Pages 972-7

McGeady ML, Siak JS, Crowell RL

Abstract

The survival of coxsackievirus B3 was studied under various conditions of incubation. The comparative study demonstrated that coxsackievirus B3 was stable for 24h (less than 0.4-log decrease in titer) when suspended at neutral pH (6 or 23 degrees C) in the presence of 0.25% bovine serum albumin in saline regardless of whether the preparations were subjected to evaporation. Bovine serum albumin provided increased stability to the virus for each of the conditions tested. At 37 degrees C, evaporation greatly reduced the virus infectivity between 6 and 20 h of incubation. Nevertheless, coxsackievirus B3 was found to be stable for at least 24 h under conditions similar to those of a household environment, and its presence represents a potential biohazard to nonimmune persons. These data provide a rationale for using coxsackievirus B3 as a model for investigating the role of environmental surfaces in the transmission of enteroviral diseases.

MeSH Terms
Culture Media Enterovirus B, Human/physiology HeLa Cells Humidity Hydrogen-Ion Concentration Osmolar Concentration Serum Albumin, Bovine Temperature
Chemicals
Culture Media Serum Albumin, Bovine
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
McGeady M L
Siak J S
Crowell R L
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21 references, click to expand
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Article Info
Journal
Applied and environmental microbiology
Abbr.
Appl Environ Microbiol
ISSN
0099-2240
DOI
10.1128/aem.37.5.972-977.1979
Published
1979-05-00
Pages
972-7
Language
English
Region
United States
NLM ID
7605801
PMCID
PMC243334
Subset
IM
External Links
PubMed source DOI: 10.1128/aem.37.5.972-977.1979 PMC Full Text View journal details
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