Home LiteratureArticle Details
PMID: 4022013 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Haploid expression of a unique c-abl transcript in the mouse male germ line.

Molecular and cellular biology ·Vol. 5 ·No. 7 ·1985-07-00 ·Pages 1791-4

Ponzetto C, Wolgemuth DJ

Abstract

RNA from immature mouse testes was shown to lack a low-molecular-weight c-abl transcript previously noted to be the predominant species in adult testes. The developmental pattern of appearance of this c-abl variant was determined by analyzing RNA obtained from purified populations of testicular cells in different stages of spermatogenesis. The appearance of the c-abl testicular variant was coincident with the entry of the germ cells into their haploid state and suggested that the regulated expression of this proto-oncogene may be important in the normal differentiation of the male germ line.

MeSH Terms
Animals Male Mice Oncogenes RNA, Messenger/genetics Sexual Maturation Spermatocytes/physiology Spermatogenesis Testis/physiology
Chemicals
RNA, Messenger
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Ponzetto C
Wolgemuth D J
References (25)
25 references, click to expand
  1. Intragenic DNA spacers interrupt the ovalbumin gene.
    Proc Natl Acad Sci U S A. 1978 Mar;75(3):1299-303 PMID: 274719
  2. Spermatogenic cells of the prepuberal mouse. Isolation and morphological characterization.
    J Cell Biol. 1977 Jul;74(1):68-85 PMID: 874003
  3. Efficient transfer of large DNA fragments from agarose gels to diazobenzyloxymethyl-paper and rapid hybridization by using dextran sulfate.
    Proc Natl Acad Sci U S A. 1979 Aug;76(8):3683-7 PMID: 291033
  4. Structure of the Abelson murine leukemia virus genome and the homologous cellular gene: studies with cloned viral DNA.
    Cell. 1980 Dec;22(3):777-85 PMID: 6257398
  5. Nucleotide and corresponding amino acid sequences encoded by alpha and beta tubulin mRNAs.
    Nature. 1981 Feb 19;289(5799):650-5 PMID: 7464932
  6. Two differentially regulated mRNAs with different 5' ends encode secreted with intracellular forms of yeast invertase.
    Cell. 1982 Jan;28(1):145-54 PMID: 7039847
  7. Differential expression of cellular oncogenes during pre- and postnatal development of the mouse.
    Nature. 1982 Oct 14;299(5884):640-4 PMID: 6289129
  8. Cellular RNA homologous to the Abelson murine leukemia virus transforming gene: expression and relationship to the viral sequence.
    Mol Cell Biol. 1983 May;3(5):773-9 PMID: 6306446
  9. cDNA clones encoding cytoplasmic poly(A)+ RNAs which first appear at detectable levels in haploid phases of spermatogenesis in the mouse.
    Dev Biol. 1983 Aug;98(2):455-64 PMID: 6688229
  10. Cellular oncogenes and retroviruses.
    Annu Rev Biochem. 1983;52:301-54 PMID: 6351725
  11. Expression of c-onc genes: c-fos transcripts accumulate to high levels during development of mouse placenta, yolk sac and amnion.
    EMBO J. 1983;2(5):679-84 PMID: 6641714
  12. Three different fibronectin mRNAs arise by alternative splicing within the coding region.
    Cell. 1983 Dec;35(2 Pt 1):421-31 PMID: 6317187
  13. A method for isolation of intact, translationally active ribonucleic acid.
    DNA. 1983;2(4):329-35 PMID: 6198133
  14. Haploid expression of a mouse testis alpha-tubulin gene.
    Science. 1984 Apr 6;224(4644):68-70 PMID: 6701535
  15. Alternative transcription and two modes of splicing results in two myosin light chains from one gene.
    Nature. 1984 Mar 22-28;308(5957):333-8 PMID: 6709041
  16. Expression of the src and abl cellular oncogenes during development of Drosophila melanogaster.
    Mol Cell Biol. 1984 May;4(5):982-4 PMID: 6203030
  17. Analysis of male sterile mutations in the mouse using haploid stage expressed cDNA probes.
    Nucleic Acids Res. 1984 May 25;12(10):4281-93 PMID: 6203099
  18. C-myc transcript is induced in rat liver at a very early stage of regeneration or by cycloheximide treatment.
    Nature. 1984 Aug 23-29;310(5979):697-8 PMID: 6472449
  19. Regulated transcription of c-Ki-ras and c-myc during compensatory growth of rat liver.
    Mol Cell Biol. 1984 Aug;4(8):1493-8 PMID: 6493228
  20. A gene sequence expressed only in undifferentiated EC, EK cells and testes.
    EMBO J. 1984 Oct;3(10):2279-85 PMID: 6209131
  21. A description of spermiogenesis in the mouse and its use in analysis of the cycle of the seminiferous epithelium and germ cell renewal.
    Am J Anat. 1956 Nov;99(3):391-413 PMID: 13402725
  22. The development of the mouse ovary from birth to maturity.
    Acta Endocrinol (Copenh). 1969 Sep;62(1):98-116 PMID: 5394354
  23. Purification of biologically active globin messenger RNA by chromatography on oligothymidylic acid-cellulose.
    Proc Natl Acad Sci U S A. 1972 Jun;69(6):1408-12 PMID: 4504350
  24. Cellular composition of fractions of mouse testis cells following velocity sedimentation separation.
    Exp Eye Res. 1973 Apr;79(1):213-27 PMID: 4575549
  25. t-Alleles and the possibility of post-meiotic gene expression during mammalian spermatogenesis.
    Fed Proc. 1978 Sep;37(11):2517-21 PMID: 357186
Article Info
Journal
Molecular and cellular biology
Abbr.
Mol Cell Biol
ISSN
0270-7306
DOI
10.1128/mcb.5.7.1791-1794.1985
Published
1985-07-00
Pages
1791-4
Language
English
Region
United States
NLM ID
8109087
PMCID
PMC367300
Subset
IM
Grants
NICHD NIH HHS · P50 HD05077 · United States
NICHD NIH HHS · R01 HD18122 · United States
NICHD NIH HHS · T32 HD07093 · United States
External Links
PubMed source DOI: 10.1128/mcb.5.7.1791-1794.1985 PMC Full Text View journal details
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2