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PMID: 406630 Published · ppublish English Journal Article

An automated method for studying exploratory and stereotyped behaviour in rats.

Psychopharmacology ·Vol. 52 ·No. 3 ·1977-05-09 ·Pages 271-7

Makanjuola RO, Hill G, Maben I, Dow RC, Ashcroft GW

Abstract

A technique is described for studying exploratory as well as stereotyped behaviour in rats using an automated hole-board. Both visual and automated recordings can be employed using the technique. Hole dipping is monitored automatically using an infra-red detector system. Repetitive patterns of hole-dipping are used as parameters of stereotyped behaviour while the more random patterns of hole-dipping are used as parameters of exploration. There was a high significant correlation between the records of hole-dipping behaviour as recorded visually and automatically. There was also a high significant correlation between the measures of repetitiveness/randomness of hole-dipping behaviour from automatic and visual recordings. The pattern and levels of hole-dipping conformed with expectations both as regards changes with time and with increasing doses of dl-amphetamine.

MeSH Terms
Amphetamines/pharmacology Animals Behavior/drug effects Exploratory Behavior/drug effects Humans Male Rats Research Design Stereotyped Behavior/drug effects
Chemicals
Amphetamines
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Makanjuola R O
Hill G
Maben I
Dow R C
Ashcroft G W
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33 references, click to expand
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Article Info
Journal
Psychopharmacology
Abbr.
Psychopharmacology (Berl)
ISSN
0033-3158
DOI
10.1007/BF00426711
Published
1977-05-09
Pages
271-7
Language
English
Region
Germany
NLM ID
7608025
Subset
IM
External Links
PubMed source DOI: 10.1007/BF00426711 View journal details
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