Home LiteratureArticle Details
PMID: 4192088 Published · ppublish English Journal Article

Genetic control of enzyme activity in higher organisms.

Biochemical genetics ·Vol. 4 ·No. 1 ·1970-02-00 ·Pages 105-25

Wyngaarden JB

Abstract

暂无摘要

MeSH Terms
Animals Arginase/biosynthesis Cell Differentiation Dactinomycin/pharmacology Dexamethasone/pharmacology Diet Enzyme Induction Enzyme Repression Enzymes/metabolism Feedback Fluorouracil/pharmacology Genes Genetic Code Gluconeogenesis Liver/metabolism Molecular Biology Protein Biosynthesis Puromycin/pharmacology RNA/metabolism Rabbits Tryptophan/pharmacology Tryptophan Oxygenase/biosynthesis Tyrosine Transaminase/biosynthesis Xanthine Oxidase/biosynthesis
Chemicals
Enzymes Dactinomycin Puromycin RNA Dexamethasone Tryptophan Tryptophan Oxygenase Xanthine Oxidase Tyrosine Transaminase Arginase Fluorouracil
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Wyngaarden J B
References (49)
49 references, click to expand
  1. Giant-size rapidly labeled nuclear ribonucleic acid and cytoplasmic messenger ribonucleic acid in immature duck erythrocytes.
    J Mol Biol. 1966 Sep;20(1):145-82 PMID: 5970657
  2. Decreased feedback inhibition in a 6-(methylmercapto)purine ribonucleoside-resistant tumor.
    Cancer Res. 1967 Oct;27(10):1773-8 PMID: 6064956
  3. Glutamine phosphoribosylpyrophosphate amidotransferase. Catalytic and conformational heterogeneity of the pigeon liver enzyme.
    Biochemistry. 1970 Mar 31;9(7):1498-505 PMID: 4314229
  4. Positive control in the L-arabinose gene-enzyme complex of Escherichia coli B/r exhibited with stable merodiploids.
    Cold Spring Harb Symp Quant Biol. 1966;31:345-7 PMID: 4866386
  5. The regulation of enzyme synthesis by steroid hormones: the role of translation.
    J Cell Physiol. 1965 Oct;66(2):Suppl 1:137-51 PMID: 4379390
  6. Genetic regulatory mechanisms in the synthesis of proteins.
    J Mol Biol. 1961 Jun;3:318-56 PMID: 13718526
  7. Interference with feedback control of enzyme activity.
    Cold Spring Harb Symp Quant Biol. 1961;26:323-9 PMID: 14476749
  8. Sequential transcription of the genes of the lactose operon and its regulation by protein synthesis.
    J Biol Chem. 1966 Oct 10;241(19):4434-43 PMID: 5332199
  9. Classification of aminotransferase (C gene) mutants in the histidine operon.
    J Mol Biol. 1966 Nov 14;21(2):335-55 PMID: 5339606
  10. The operon concept in bacteria and in higher organisms.
    Natl Cancer Inst Monogr. 1967 Nov;27:221-34 PMID: 5583766
  11. Differential effects of fasting and protein-free diets on levels of urea cycle enzymes in rat liver.
    J Biol Chem. 1962 Jun;237:1921-4 PMID: 14498420
  12. Frameshift mutations in the lactose operon of E. coli.
    Cold Spring Harb Symp Quant Biol. 1966;31:189-201 PMID: 4866375
  13. The interaction of RNA polymerase with histones.
    Proc Natl Acad Sci U S A. 1969 Apr;62(4):1218-25 PMID: 5256418
  14. Effect of inhibitors of nucleic acid synthesis on steroid-mediated induction of tyrosine aminotransferase in hepatoma cell cultures.
    J Mol Biol. 1967 Nov 28;30(1):49-61 PMID: 4383907
  15. Allosteric proteins and cellular control systems.
    J Mol Biol. 1963 Apr;6:306-29 PMID: 13936070
  16. Tyrosine transaminase induction in mammalian cells in tissue culture.
    Cold Spring Harb Symp Quant Biol. 1966;31:349-60 PMID: 4295324
  17. THE ENZYMOLOGY OF FEEDBACK INHIBITION OF GLUTAMINE PHOSPHORIBOSYLPYROPHOSPHATE AMIDOTRANSFERASE BY PURINE RIBONUCLEOTIDES.
    J Biol Chem. 1964 Aug;239:2570-9 PMID: 14235537
  18. Variations in purine metabolism of cultured skin fibroblasts from patients with gout.
    J Clin Invest. 1968 Jul;47(7):1511-6 PMID: 5658584
  19. Histone phosphorylation: stimulation by adenosine 3',5'-monophosphate.
    Science. 1968 Nov 1;162(3853):579-80 PMID: 4303296
  20. Glutamine phosphoribosylpyrophosphate amidotransferase. Purification, substructure, amino acid composition, and absorption spectra.
    J Biol Chem. 1968 Dec 25;243(24):6373-83 PMID: 4302392
  21. An analysis of the kinetics of rat liver tryptophan pyrrolase induction: the significance of both enzyme synthesis and degradation.
    Biochem Biophys Res Commun. 1964 Mar 26;15(3):214-9 PMID: 5835384
  22. Induction of tyrosine alpha-ketoglutarate transaminase by steroid hormones in a newly established tissue culture cell line.
    Proc Natl Acad Sci U S A. 1966 Jul;56(1):296-303 PMID: 4381784
  23. Evidence for the steroid-induced accumulation of tyrosine-aminotransferase messenger RNA in the absence of protein synthesis.
    Proc Natl Acad Sci U S A. 1968 May;60(1):222-8 PMID: 4385387
  24. Structural organization of nuclear complexes containing DNA-like RNA.
    J Mol Biol. 1968 Apr 14;33(1):251-63 PMID: 5646646
  25. Alternative modes of derepression of the histidine operon observed in Salmonella typhimurium.
    J Biol Chem. 1966 Oct 10;241(19):4426-33 PMID: 5332198
  26. Nonsense mutants and polarity in the lac operon of Escherichia coli.
    J Mol Biol. 1965 Nov;14(1):290-6 PMID: 5327654
  27. ON THE NATURE OF ALLOSTERIC TRANSITIONS: A PLAUSIBLE MODEL.
    J Mol Biol. 1965 May;12 :88-118 PMID: 14343300
  28. False feedback inhibition: inhibition of tryptophan biosynthesis by 5-methyltryptophan.
    J Biol Chem. 1960 Apr;235:1098-102 PMID: 14424820
  29. The L-arabinose operon in Escherichia coli B-r: a genetic demonstration of two functional states of the product of a regulator gene.
    Proc Natl Acad Sci U S A. 1969 Apr;62(4):1100-7 PMID: 4894687
  30. ISOLATION OF THE lambda PHAGE REPRESSOR.
    Proc Natl Acad Sci U S A. 1967 Feb;57(2):306-13 PMID: 16591470
  31. THE ROLES OF SYNTHESIS AND DEGRADATION IN THE CONTROL OF RAT LIVER TRYPTOPHAN PYRROLASE.
    J Biol Chem. 1965 Jan;240:322-31 PMID: 14253432
  32. On the transcription of the tryptophan operon in Escherichia coli. II. Production of the specific messenger RNA.
    J Mol Biol. 1965 Aug;13(1):157-68 PMID: 5323612
  33. A PARADOXICAL EFFECT OF ACTINOMYCIN D: THE MECHANISM OF REGULATION OF ENZYME SYNTHESIS BY HYDROCORTISONE.
    Proc Natl Acad Sci U S A. 1964 Oct;52:1121-9 PMID: 14224391
  34. The hormonal control of tryptophan peroxidase in the rat.
    J Biol Chem. 1955 May;214(1):307-13 PMID: 14367389
  35. Isolation of the lac repressor.
    Proc Natl Acad Sci U S A. 1966 Dec;56(6):1891-8 PMID: 16591435
  36. The mechanism of dietary alterations in rat hepatic xanthine oxidase levels.
    J Biol Chem. 1966 Dec 10;241(23):5571-6 PMID: 5928198
  37. The lac operator is DNA.
    Proc Natl Acad Sci U S A. 1967 Dec;58(6):2415-21 PMID: 4873589
  38. Nonsense codons and polarity in the tryptophan operon.
    J Mol Biol. 1966 Nov 14;21(2):313-34 PMID: 5339605
  39. THE IMPORTANCE OF BOTH SYNTHESIS AND DEGRADATION IN THE CONTROL OF ARGINASE LEVELS IN RAT LIVER.
    J Biol Chem. 1964 Nov;239:3808-17 PMID: 14257612
  40. Application of genetic regulatory mechanisms to human genetics.
    Am J Med. 1963 May;34:680-91 PMID: 13941505
  41. Synthesis and induction of tyrosine aminotransferase in synchronized hepatoma cells in culture.
    Proc Natl Acad Sci U S A. 1969 Jan;62(1):248-55 PMID: 4388856
  42. Studies on the induction and repression of enzymes in rat liver. V. Regulation of the rate of synthesis and degradation of serine dehydratase by dietary amino acids and glucose.
    J Biol Chem. 1968 Jun 10;243(11):3057-66 PMID: 4968185
  43. Polarity in the histidine operon.
    J Mol Biol. 1966 Nov 14;21(2):357-69 PMID: 4291404
  44. Environmental control of enzyme synthesis and degradation.
    J Cell Physiol. 1965 Oct;66(2):Suppl 1:11-22 PMID: 5863362
  45. Adaptation of the rat liver tyrosine-alpha-ketoglutarate transaminase.
    Biochim Biophys Acta. 1957 Oct;26(1):85-8 PMID: 13479464
  46. THE OPERON: ON ITS THIRD ANNIVERSARY. MODULATION OF TRANSFER RNA SPECIES CAN PROVIDE A WORKABLE MODEL OF AN OPERATOR-LESS OPERON.
    Science. 1964 May 15;144(3620):816-20 PMID: 14149392
  47. Sequential biosynthesis of the peptide chains of hemoglobin.
    Proc Natl Acad Sci U S A. 1962 Oct 15;48:1822-30 PMID: 13937734
  48. STUDIES ON THE INDUCTION AND REPRESSION OF ENZYMES IN RAT LIVER. 3. INDUCTION OF ORNITHINE DELTA-TRANSAMINASE AND THREONINE DEHYDRASE BY ORAL INTUBATION OF FREE AMINO ACIDS.
    J Biol Chem. 1965 Jul;240:3039-43 PMID: 14342330
  49. An inherited molecular lesion of erythrocyte pyruvate kinase. Identification of a kinetically aberrant isozyme associated with premature hemolysis.
    J Clin Invest. 1968 Aug;47(8):1929-46 PMID: 5666119
Article Info
Journal
Biochemical genetics
Abbr.
Biochem Genet
ISSN
0006-2928
DOI
10.1007/BF00484024
Published
1970-02-00
Pages
105-25
Language
English
Region
United States
NLM ID
0126611
Subset
IM
External Links
PubMed source DOI: 10.1007/BF00484024 View journal details
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2