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PMID: 4207520 Published · ppublish English Journal Article

Rickettsial infectious antibody complexes: detection by antiglobulin plaque reduction technique.

Infection and immunity ·Vol. 9 ·No. 5 ·1974-05-00 ·Pages 966-8

Kenyon RH, McManus AT

Abstract

Rickettsia rickettsii and R. australis formed infectious antibody complexes when reacted with homologous convalescent serum. The addition of antiglobulin to these complexes showed neutralization of plaques proportional to the concentration of rickettsial immune serum.

MeSH Terms
Animals Antibodies, Anti-Idiotypic Antigen-Antibody Complex Goats/immunology Haplorhini/immunology Humans Immune Sera Neutralization Tests Rickettsia/immunology,pathogenicity Rickettsia Infections/immunology Viral Plaque Assay
Chemicals
Antibodies, Anti-Idiotypic Antigen-Antibody Complex Immune Sera
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Kenyon R H
McManus A T
References (6)
6 references, click to expand
  1. Assay of Coxiella burnetii by enumeration of immunofluorescent infected cells.
    J Immunol. 1966 Oct;97(4):492-7 PMID: 5334247
  2. Titration and neutralization of Rickettsia tsutsugamushi in tissue culture.
    J Immunol. 1968 Apr;100(4):825-30 PMID: 4967048
  3. Plaque assay for Rickettsia rickettsii.
    J Bacteriol. 1969 May;98(2):398-402 PMID: 4977475
  4. Preparation of vaccines for Rocky Mountain spotted fever from rickettsiae propagated in cell culture.
    J Infect Dis. 1972 Feb;125(2):146-52 PMID: 4621411
  5. Mechanisms of immunity in typhus infections. 3. Influence of human immune serum and complement on the fate of Rickettsia mooseri within the human macrophages.
    Infect Immun. 1973 Oct;8(4):631-40 PMID: 4795469
  6. The influence of certain salts, amino acids, sugars, and proteins on the stability of rickettsiae.
    J Bacteriol. 1950 Apr;59(4):509-22 PMID: 15436424
Article Info
Journal
Infection and immunity
Abbr.
Infect Immun
ISSN
0019-9567
DOI
10.1128/iai.9.5.966-968.1974
Published
1974-05-00
Pages
966-8
Language
English
Region
United States
NLM ID
0246127
PMCID
PMC414916
Subset
IM
External Links
PubMed source DOI: 10.1128/iai.9.5.966-968.1974 PMC Full Text View journal details
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