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PMID: 4347930 Published · ppublish English Journal Article

Time of enterotoxin formation and release during sporulation of Clostridium perfringens type A.

Journal of bacteriology ·Vol. 113 ·No. 2 ·1973-02-00 ·Pages 932-6

Duncan CL

Abstract

Clostridium perfringens enterotoxin was detected intracellularly about 3 hr after the inoculation of vegetative cells into sporulation medium. The subsequent increase in intracellular enterotoxin concentration roughly paralleled but followed by 2.5 to 5 hr the increase in number of heat-resistant spores. The increase in biologically active toxin coincided with the increase in enterotoxin antigen. Enterotoxin was released from the sporangium with its lysis, concomitantly with the mature spore release.

MeSH Terms
Animals Antigens, Bacterial/analysis Clostridium perfringens/growth & development,metabolism Culture Media Enterotoxins/analysis,biosynthesis Guinea Pigs Hot Temperature Immunodiffusion Skin Tests Spores, Bacterial/growth & development Thioglycolates Time Factors
Chemicals
Antigens, Bacterial Culture Media Enterotoxins Thioglycolates
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Duncan C L
References (14)
14 references, click to expand
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Article Info
Journal
Journal of bacteriology
Abbr.
J Bacteriol
ISSN
0021-9193
Published
1973-02-00
Pages
932-6
Language
English
Region
United States
NLM ID
2985120R
PMCID
PMC285311
Subset
IM
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