Home LiteratureArticle Details
PMID: 4372403 Published · ppublish English Journal Article

Nucleic acid homology of murine type-C viral genes.

Journal of virology ·Vol. 14 ·No. 6 ·1974-12-00 ·Pages 1394-403

Callahan R, Benveniste RE, Lieber MM, Todaro GJ

Abstract

The nucleic acid sequence homology between various murine, endogenous type-C viruses (three host range classes of BALB/c virus, the AT-124 virus, and the CCL 52 virus) and two laboratory strains of murine leukemia virus (Rauscher and Kirsten) was determined by DNA:RNA hybridization. The viral sequences exhibit varying degrees of partial homology. DNA:DNA hybridizations were performed between [(3)H]DNA probes prepared from N- and X-tropic BALB/c endogenous viruses and cellular DNAs from BALB/c, NIH Swiss, and AKR inbred mouse strains as well as from California feral mice and the Asian mouse subspecies Mus musculus molossinus and M. musculus castaneus. All of these strains of mice are shown to possess multiple (six to seven per haploid genome), partially related copies of type-C virogenes in their DNAs. Thermal melting profiles of the DNA:RNA and DNA:DNA hybrids suggest that the partial homology of the viral nucleic acid sequences is the result of base alterations throughout the viral genomes, rather than the loss of discrete segments of viral sequences.

MeSH Terms
Animals Base Sequence Cell Line Cornea Dogs Fibroblasts Gammaretrovirus Genes Hot Temperature Mice Mice, Inbred Strains/embryology Nucleic Acid Hybridization RNA, Viral Rabbits Retroviridae Thymus Gland
Chemicals
RNA, Viral
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Callahan R
Benveniste R E
Lieber M M
Todaro G J
References (29)
29 references, click to expand
  1. Host-range restrictions of murine leukemia viruses in mouse embryo cell cultures.
    J Virol. 1970 Feb;5(2):221-5 PMID: 4317349
  2. The presence of unique DNA sequences after viral induction of leukemia in mice. (RNA tumor virus-nucleic acid hybridization-insertion of viral DNA).
    Proc Natl Acad Sci U S A. 1974 May;71(5):1705-9 PMID: 4525459
  3. Repeated demonstration of a mouse leukemia virus after treatment with chemical carcinogens.
    J Natl Cancer Inst. 1971 Apr;46(4):751-62 PMID: 4324812
  4. Leukemia virus release in chemically or physically induced lymphomas in BALB-c mice.
    Natl Cancer Inst Monogr. 1966 Sep;22:701-11 PMID: 4288571
  5. Spontaneous release of type C viruses from clonal lines of spontaneously transformed Blab-3T3 cells.
    Nat New Biol. 1972 Nov 29;240(100):157-60 PMID: 4118366
  6. Mammalian cells in culture frequently release type C viruses.
    Science. 1973 Oct 5;182(4107):56-9 PMID: 4125845
  7. Infidelity of DNA synthesis by reverse transcriptase.
    Biochem Biophys Res Commun. 1973 May 15;52(2):401-6 PMID: 4123058
  8. A distinct class of inducible murine type-C viruses that replicates in the rabbit SIRC cell line.
    Proc Natl Acad Sci U S A. 1974 Mar;71(3):602-6 PMID: 4132531
  9. Induction of murine C-type viruses from clonal lines of virus-free BALB-3T3 cells.
    Science. 1971 Oct 8;174(4005):157-9 PMID: 5119627
  10. Detection of baboon type C viral sequences in various primate tissues by molecular hybridization.
    J Virol. 1974 Jul;14(1):56-67 PMID: 4365323
  11. Expression of malignancy in interspecies Chinese hamster X mouse cell hybrids.
    J Natl Cancer Inst. 1973 Sep;51(3):781-92 PMID: 4355218
  12. Xenotropic viruses: murine leukemia viruses associated with NIH Swiss, NZB, and other mouse strains.
    Science. 1973 Dec 14;182(4117):1151-3 PMID: 4356281
  13. Characterization of murine leukaemia virus-specific DNA present in normal mouse cells.
    Nat New Biol. 1973 Jul 18;244(133):76-9 PMID: 4352888
  14. Repeated sequences in DNA. Hundreds of thousands of copies of DNA sequences have been incorporated into the genomes of higher organisms.
    Science. 1968 Aug 9;161(3841):529-40 PMID: 4874239
  15. Leukemogenic activity of filtrates from radiation-induced lymphoid tumors of mice.
    Science. 1959 Aug 14;130(3372):387-8 PMID: 13675761
  16. Related base sequences in the DNA of simple and complex organisms. VI. The extent of base sequence divergence among the DNAs of various rodents.
    Biochem Genet. 1970 Jun;4(3):425-46 PMID: 4991032
  17. A type-C virus in human rhabdomyosarcoma cells after inoculation into NIH Swiss mice treated with antithymocyte serum.
    Proc Natl Acad Sci U S A. 1973 Mar;70(3):859-62 PMID: 4123693
  18. Relatedness of mouse satellite deoxyribonucleic acid to deoxyribonucleic acid of various Mus species.
    Proc Natl Acad Sci U S A. 1973 Dec;70(12):3546-50 PMID: 4519644
  19. Independent segregation of loci for activation of biologically distinguishable RNA C-type viruses in mouse cells.
    Proc Natl Acad Sci U S A. 1973 Jul;70(7):2055-8 PMID: 4352968
  20. RNA in mammalian sarcoma virus transformed nonproducer cells homologous to murine leukemia virus RNA.
    Virology. 1973 Feb;51(2):370-82 PMID: 4120907
  21. Release of C-type particles from normal rat thymus cultures and those infected with Moloney leukemia virus.
    J Natl Cancer Inst. 1971 Jan;46(1):11-23 PMID: 4251036
  22. Homology between type-C viruses of various species as determined by molecular hybridization.
    Proc Natl Acad Sci U S A. 1973 Dec;70(12):3316-20 PMID: 4357865
  23. S-tropic murine type-C viruses: frequency of isolation from continuous cell lines, leukemia virus preparations and normal spleens.
    Int J Cancer. 1974 May 15;13(5):587-98 PMID: 4135772
  24. Evidence that the AKR murine-leukemia-virus genome is complete in DNA of the high-virus AKR mouse and incomplete in the DNA of the "virus-negative" NIH mouse.
    Proc Natl Acad Sci U S A. 1974 Jan;71(1):167-71 PMID: 4359326
  25. Prevalence of the group-specific (gs) antigen and infectious virus expressions of the murine C-type RNA viruses during the life span of BALB-cCr mice.
    Int J Cancer. 1972 Sep 15;10(2):283-9 PMID: 4122307
  26. "Spontaneous" leukemia developing in C3H mice following inoculation in infancy, with AK-leukemic extracts, or AK-embrvos.
    Proc Soc Exp Biol Med. 1951 Jan;76(1):27-32 PMID: 14816382
  27. [Serial cell-free passage of a radiation-activated mouse leukemia agent].
    Proc Soc Exp Biol Med. 1959 Jan;100(1):102-5 PMID: 13634050
  28. A virus-induced disease of mice characterized by erythrocytopoiesis and lymphoid leukemia.
    J Natl Cancer Inst. 1962 Sep;29:515-43 PMID: 14490596
  29. Reduction in the rate of DNA reassociation by sequence divergence.
    J Mol Biol. 1973 Dec 5;81(2):123-35 PMID: 4591183
Article Info
Journal
Journal of virology
Abbr.
J Virol
ISSN
0022-538X
DOI
10.1128/JVI.14.6.1394-1403.1974
Published
1974-12-00
Pages
1394-403
Language
English
Region
United States
NLM ID
0113724
PMCID
PMC355667
Subset
IM
External Links
PubMed source DOI: 10.1128/JVI.14.6.1394-1403.1974 PMC Full Text View journal details
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2