Home LiteratureArticle Details
PMID: 4455477 Published · ppublish English Journal Article

Folic acid deficiency and epilepsy.

Drugs ·Vol. 8 ·No. 5 ·1974-00-00 ·Pages 366-85

Norris JW, Pratt RF

Abstract

暂无摘要

MeSH Terms
Abnormalities, Drug-Induced/etiology Absorption Anticonvulsants/adverse effects,therapeutic use Brain/metabolism Epilepsy/complications,drug therapy Female Folic Acid/metabolism Folic Acid Deficiency/complications Humans Mental Disorders/etiology Pregnancy Pregnancy Complications/etiology
Chemicals
Anticonvulsants Folic Acid
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Norris J W
Pratt R F
References (79)
79 references, click to expand
  1. A controlled study of folic acid in epilepsy. A controlled study of folic acid in epilepsy.
    Neurology. 1971 Jun;21(6):659-64 PMID: 4934771
  2. Interrelationships of vitamin B12 and folate in man.
    Am J Med. 1970 May;48(5):555-61 PMID: 4912929
  3. Absorption of unaltered folic acid from the gastro-intestinal tract in man.
    Br J Haematol. 1967 Sep;13(5):679-86 PMID: 6050860
  4. Conventional voltage electrophoresis for formiminoglutamic-acid determination in folic acid deficiency.
    J Clin Pathol. 1961 Jul;14:345-50 PMID: 13757596
  5. Effects of folic acid on fit-frequency and behaviour in epileptics on anticonvulsants.
    Lancet. 1970 Apr 25;1(7652):867-8 PMID: 4191511
  6. Relation of dosage and time of administration of diphenylhydantoin to its teratogenic effect in mice.
    Teratology. 1969 Nov;2(4):305-11 PMID: 5362424
  7. Epilepsy and folate deficiency.
    Br Med J. 1969 Dec 27;4(5686):807-8 PMID: 5359954
  8. Folic acid and neuropathy in epilepsy.
    Lancet. 1967 Dec 16;2(7529):1305-6 PMID: 4168628
  9. Effect of folic-acid supplement on serum-vitamin-B12 levels in patients on anticonvulsants.
    Lancet. 1969 Sep 27;2(7622):666-7 PMID: 4185411
  10. Brain folate concentration in folate-deficient rats receiving diphenylhydantoin.
    Neurology. 1970 Apr;20(4):403 PMID: 5535044
  11. Absorption and utilization of polyglutamyl forms of folate in man.
    Br Med J. 1968 Nov 30;4(5630):546-9 PMID: 5722315
  12. Further evidence on the nature of prefolic A.
    Biochem Biophys Res Commun. 1961 Jul 26;5:289-92 PMID: 13723690
  13. Folic acid deficiency and congenital malformation.
    J Obstet Gynaecol Br Commonw. 1972 Feb;79(2):159-61 PMID: 5038033
  14. Rare complication of phenytoin sodium treatment.
    Br Med J. 1956 Dec 29;2(5008):1529 PMID: 13374374
  15. Placental transfer of phenobarbitone in epileptic women, and elimination in newborns.
    Lancet. 1967 Oct 21;2(7521):860-1 PMID: 12387244
  16. Isolated defect of folic acid absorption associated with mental retardation and cerebral calcification.
    Blood. 1969 Oct;34(4):452-65 PMID: 4980683
  17. Congenital malformations among infants born to epileptic women.
    Lancet. 1973 Jan 6;1(7793):9-10 PMID: 4118585
  18. Maternal epilepsy and abnormalities of the fetus and newborn.
    Lancet. 1972 Oct 21;2(7782):839-43 PMID: 4116552
  19. The megaloblastic anemias.
    Annu Rev Med. 1960;11:333-52 PMID: 14423429
  20. MEGALOBLASTIC ANEMIA IN PREGNANCY AND THE PUERPERIUM.
    Am J Obstet Gynecol. 1964 Jun 15;89:532-4 PMID: 14168993
  21. Folic acid and anticonvulsants.
    Lancet. 1969 Jan 25;1(7587):207-8 PMID: 4178451
  22. Lactobacillus casei C.S.F. folate activity.
    Br Med J. 1967 Sep 30;3(5569):834-6 PMID: 6036432
  23. Transport characteristics of folates in cerebrospinal fluid; a study utilizing doubly labeled 5-methyltetrahydrofolate and 5-formyltetrahydrofolate.
    J Clin Invest. 1971 Jun;50(6):1301-8 PMID: 5314166
  24. Lack of effect of folic-acid administration on cerebral metabolism.
    Lancet. 1971 Oct 9;2(7728):798-800 PMID: 4106611
  25. Folic acid in folate-deficient patients with epilepsy.
    Br Med J. 1970 Dec 12;4(5736):644-8 PMID: 4922754
  26. NEUROLOGICAL SEQUELAE FOLLOWING DILANTIN OVERDOSE IN A PATIENT AND IN EXPERIMENTAL ANIMALS.
    Neurology. 1965 Sep;15:823-9 PMID: 14334957
  27. Experimental nutritional folate deficiency in man.
    Trans Assoc Am Physicians. 1962;75:307-20 PMID: 13953904
  28. Subnormal serum folate due to anticonvulsive therapy. A double-blind study of the effect of folic acid treatment in patients with drug-induced subnormal serum folates.
    Arch Neurol. 1970 Feb;22(2):181-2 PMID: 4902774
  29. Studies on the identification of a folate compound of human serum.
    J Clin Invest. 1962 May;41:1134-8 PMID: 13906633
  30. Folic acid metabolism.
    Physiol Rev. 1967 Jan;47(1):83-116 PMID: 5343223
  31. Anticonvulsant drugs in human epileptogenic brain. Correlation of phenobarbital and diphenylhydantoin levels with plasma.
    Arch Neurol. 1973 Aug;29(2):73-7 PMID: 4197955
  32. The absorption of some B-group vitamins by surviving rat intestine preparations.
    Q J Exp Physiol Cogn Med Sci. 1962 Apr;47:107-33 PMID: 13923209
  33. MEGALOBLASTIC ANEMIA AND NEUROLOGIC DISTURBANCES COMBINED WITH FOLIC ACID DEFICIENCY. OBSERVATIONS ON AN EPILEPTIC PATIENT TREATED WITH ANTICONVULSANTS.
    Acta Med Scand. 1964 Aug;176:243-51 PMID: 14213892
  34. URINARY FORMIMINO-GLUTAMIC ACID EXCRETION IN PREGNANCY.
    Br Med J. 1963 Nov 2;2(5365):1103-4 PMID: 14060147
  35. Megaloblastic anaemia due to phenytoin sodium.
    Lancet. 1954 Oct 9;267(6841):737-8 PMID: 13202487
  36. Anticonvulsant drugs and congenital abnormalities.
    Lancet. 1968 Dec 14;2(7581):1296 PMID: 4177489
  37. Intestinal conversion of folinic acid to 5-methyltetrahydrofolate in man.
    Br J Haematol. 1972 Jan;22(1):63-72 PMID: 4621839
  38. The assay and nature of folic acid activity in human serum.
    J Clin Invest. 1961 Jan;40:81-91 PMID: 13713522
  39. Formiminotransferase-deficiency syndrome: a new inborn error of folic acid metabolism.
    Ann Paediatr. 1965;205(1):1-11 PMID: 5897668
  40. Megaloblastic anaemia due to phenobarbitone; the convulsant action of therapeutic doses of folic acid.
    Br Med J. 1960 Apr 9;1(5179):1099-102 PMID: 13809099
  41. Associations between drugs administered during pregnancy and congenital abnormalities of the fetus.
    Br Med J. 1971 Mar 6;1(5748):523-7 PMID: 4396080
  42. Results of intensive (narcosis) and standard medical treatment of epilepsy.
    J Am Med Assoc. 1953 Aug 8;152(15):1400-6 PMID: 13061286
  43. Dementia and folate deficiency.
    Q J Med. 1967 Apr;36(142):189-204 PMID: 5340551
  44. Folic acid and neuropathy in epilepsy.
    Lancet. 1968 Jan 20;1(7534):146 PMID: 4169634
  45. Psychiatric syndromes due to avitaminosis B 12 with normal blood and marrow.
    Q J Med. 1965 Jul;34(135):303-17 PMID: 5838263
  46. Pharmacology and mechanisms of action of diphenylhydantoin.
    Psychiatr Neurol Neurochir. 1971 Mar-Apr;74(2):91-115 PMID: 4338044
  47. Anticonvulsant-associated megaloblastic anemia. Response to 25 microgm. of folic acid administered by mouth daily.
    N Engl J Med. 1962 Sep 6;267:483-5 PMID: 13887968
  48. A microbiologic method for detecting folic acid deficiency in man.
    Clin Chem. 1959 Aug;5(4):275-80 PMID: 13671739
  49. Evidence for reduction and methylation of folate in the intestine during normal absorption.
    Lancet. 1969 Oct 11;2(7624):776-8 PMID: 4186025
  50. Schizophrenia-like psychoses of epilepsy and disturbances of folate and vitamin B12 metabolism induced by anticonvulsant drugs.
    Br J Psychiatry. 1967 Aug;113(501):911-9 PMID: 6048376
  51. New light on pernicious anaemia.
    Lancet. 1973 Sep 8;2(7828):538-9 PMID: 4125298
  52. Folates in plasma and bile of man after feeding folic acid--3H and 5-formyltetrahydrofolate (folinic acid).
    J Clin Invest. 1971 Feb;50(2):455-62 PMID: 4992993
  53. The schizophrenialike psychoses of epilepsy.
    Br J Psychiatry. 1963 Jan;109:95-150 PMID: 13989174
  54. Diphenylhydantoin and selected congenital malformations.
    N Engl J Med. 1973 Nov 15;289(20):1049-52 PMID: 4742220
  55. Absorption of polyglutamic folate: participation of deconjugating enzymes of the intestinal mucosa.
    N Engl J Med. 1969 May 1;280(18):985-8 PMID: 5777925
  56. An evaluation of aminopterin as an abortifacient.
    Am J Obstet Gynecol. 1962 Jun 1;83:1474-7 PMID: 13899497
  57. Effects of folic acid on the mental state and fit-frequency of drug-treated epileptic patients.
    Lancet. 1967 May 20;1(7499):1086-8 PMID: 4164775
  58. Folate deficiency and neurological disease.
    Lancet. 1965 Oct 16;2(7416):763-7 PMID: 4157811
  59. Mental deterioration in epilepsy due to folate deficiency.
    Br Med J. 1970 Jun 27;2(5712):759-61 PMID: 5428738
  60. Folic acid deficiency: early onset of megaloblastosis.
    JAMA. 1972 Oct;222(4):490 PMID: 4627560
  61. Folate therapy in epilepsy. A controlled study.
    Arch Neurol. 1973 Aug;29(2):78-81 PMID: 4577819
  62. Folate metabolism and the anticonvulsant efficacy of phenobarbital.
    Arch Neurol. 1973 Jan;28(1):18-22 PMID: 4682068
  63. Congenital anomalies due to attempted abortion with 4-aminopteroglutamic acid.
    J Am Med Assoc. 1956 Jul 28;161(13):1253 PMID: 13331791
  64. SUBNORMAL SERUM FOLATE AND MACROCYTOSIS ASSOCIATED WITH ANTICONVULSANT DRUG THERAPY.
    Blood. 1964 Jan;23:68-86 PMID: 14107052
  65. Radioactive vitamin B12 absorption in the megaloblastic anaemia caused by anticonvulsant drugs.
    Q J Med. 1961 Jul;30:231-48 PMID: 13760309
  66. Anticonvulsant therapy, folic acid and vitamin B12 metabolism and mental symptoms.
    Epilepsia. 1966 Dec;7(4):261-70 PMID: 5227261
  67. Serum folic-acid and vitamin-B12 levels in anticonvulsant therapy.
    Br Med J. 1966 Apr 16;1(5493):955-7 PMID: 20790923
  68. Folate deficiency and neurological disease. One case with a close association.
    Arch Neurol. 1974 Mar;30(3):263-5 PMID: 4360146
  69. Mental retardation with hyperfolic-acidemia not associated with formiminoglutamic-acciduria: cyclohydrolase deficiency syndrome.
    Tohoku J Exp Med. 1966 Apr 25;88(4):341-52 PMID: 5954919
  70. Absorption of folic acid from the small intestine of the rat.
    Br J Pharmacol Chemother. 1962 Oct;19:313-20 PMID: 14016958
  71. Mental effects of anticonvulsants, and folic acid metabolism.
    Brain. 1968 Jun;91(2):197-214 PMID: 5721926
  72. Macrocytosis and macrocytic anaemia caused by anticonvulsant drugs.
    Q J Med. 1958 Jan;27(105):45-63 PMID: 13506010
  73. Folic acid and anticonvulsive drugs.
    Arch Neurol. 1969 Aug;21(2):208-14 PMID: 5797353
  74. Method of assay of red cell folate activity and the value of the assay as a test for folate deficiency.
    J Clin Pathol. 1966 Jan;19(1):17-28 PMID: 5904976
  75. IATROGENIC MEGALOBLASTIC ANAEMIA WITH NEUROLOGICAL COMPLICATIONS.
    Scott Med J. 1964 Sep;9:388-90 PMID: 14200165
  76. Absorption of crystalline folic acid in man.
    Lancet. 1968 Aug 10;2(7563):302-6 PMID: 4173731
  77. The use of labelled vitamin B12 and gastric biopsy in the investigation of anaemia.
    Proc R Soc Med. 1954 Jun;47(6):426-7 PMID: 13177546
  78. [Hemopoietic complications of hydantoin therapy of epilepsy].
    Med Klin. 1952 Oct 17;47(42):1397-1401 PMID: 13001915
  79. B 12 dependence of cell uptake of serum folate: an explanation for high serum folate and cell folate depletion in B 12 deficiency.
    Blood. 1973 Mar;41(3):465-9 PMID: 4690144
Article Info
Journal
Drugs
Abbr.
Drugs
ISSN
0012-6667
Published
1974-00-00
Pages
366-85
Language
English
Region
New Zealand
NLM ID
7600076
Subset
IM
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]