Ferritinaemia in leukaemia and Hodgkin's disease.

British journal of cancer ·Vol. 27 ·No. 3 ·1973-03-00 ·Pages 212-7

Jones PA, Miller FM, Worwood M, Jacobs A

Abstract

The serum ferritin concentration is increased in both acute myeloblastic leukaemia and Hodgkin's disease. In acute leukaemia the mean concentration is about ten times the normal level and is associated with a high concentration of transferrin-bound iron. In Hodgkin's disease abnormal ferritinaemia is associated with a low concentration of transferrin-bound iron and appears to result from a block of reticuloendothelial iron release. Increased concentrations of circulating ferritin have also been observed in a few cases of chronic leukaemia and myelomatosis.

MeSH Terms

Acute Disease Anemia/blood Chronic Disease Female Ferritins/blood Hodgkin Disease/blood Humans Leukemia/blood Leukemia, Myeloid, Acute/blood Leukocyte Count Male Multiple Myeloma/blood

Chemicals

Ferritins

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Jones P A

Miller F M

Worwood M

Jacobs A

References (13)

13 references, click to expand

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Ferritin in body fluids.
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Elevated serum iron, low unbound transferrin and candidiasis in acute leukemia.
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The anaemia of chronic disorders.
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The measurement of reticuloendothelial iron release using iron-dextran.
Br J Haematol. 1971 Dec;21(6):617-22 PMID: 5132947
An immunoradiometric assay for ferritin in the serum of normal subjects and patients with iron deficiency and iron overload.
J Clin Pathol. 1972 Apr;25(4):326-9 PMID: 5063755
Ferritin in the serum of normal subjects and patients with iron deficiency and iron overload.
Br Med J. 1972 Oct 28;4(5834):206-8 PMID: 5082548
Iron metabolism in Hodgkin's disease.
Br J Cancer. 1972 Dec;26(6):444-52 PMID: 4567182
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Blood. 1959 Aug;14(8):935-49 PMID: 13671087
METHOD FOR THE AUTOMATIC DETERMINATION OF SERUM IRON.
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Article Info

Journal

British journal of cancer

Abbr.

Br J Cancer

ISSN

0007-0920

DOI

10.1038/bjc.1973.26

Published

1973-03-00

Pages

212-7

Language

English

Region

England

NLM ID

0370635

PMCID

PMC2008776

Subset

External Links

PubMed source DOI: 10.1038/bjc.1973.26 PMC Full Text View journal details

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