Home LiteratureArticle Details
PMID: 4524642 Published · ppublish English Journal Article

Synthesis of complementary strands of heterologous RNAs with Qbeta replicase.

Palmenberg A, Kaesberg P

Abstract

Qbeta replicase, in the presence of Mn(++), can use various RNAs as templates for synthesis of full-length RNA products and can also use Qbeta plus-strand RNA as template in the absence of host factors.

MeSH Terms
Base Sequence Coliphages/enzymology DNA-Directed RNA Polymerases/metabolism Electrophoresis, Polyacrylamide Gel Magnesium Manganese RNA/analysis,biosynthesis RNA Viruses/enzymology RNA, Ribosomal RNA, Transfer RNA, Viral/biosynthesis Ribonucleotides/metabolism Templates, Genetic Tritium
Chemicals
RNA, Ribosomal RNA, Viral Ribonucleotides Tritium Manganese RNA RNA, Transfer DNA-Directed RNA Polymerases Magnesium
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Palmenberg A
Kaesberg P
References (27)
27 references, click to expand
  1. Replication of RNA viruses. X. Replication of a natural 6 s RNA by the Q-beta RNA polymerase.
    J Mol Biol. 1969 Oct 28;45(2):181-93 PMID: 4904405
  2. Factor fraction required for the synthesis of bacteriophage Qbeta-RNA.
    Nature. 1968 Aug 10;219(5154):588-90 PMID: 4874917
  3. REPLICATION OF RNA VIRUSES I. CHARACTERIZATION OF A VIRAL RNA-DEPENDENT RNA POLYMERASE.
    J Mol Biol. 1965 Feb;11:257-71 PMID: 14290344
  4. Bacterial proteins required for replication of phage Q ribonucleic acid. Pruification and properties of host factor I, a ribonucleic acid-binding protein.
    J Biol Chem. 1972 Feb 10;247(3):824-31 PMID: 4550762
  5. Synthesis of bacteriophage Q-beta RNA.
    Cold Spring Harb Symp Quant Biol. 1968;33:73-81 PMID: 5254583
  6. Purification of viral RNA by means of bentonite.
    Virology. 1961 May;14:54-8 PMID: 13701154
  7. Subunit structure of Q-beta replicase.
    Nature. 1970 Nov 7;228(5271):525-7 PMID: 5472467
  8. PHYSICAL AND CHEMICAL PROPERTIES OF RNA FROM THE BACTERIAL VIRUS R17.
    Proc Natl Acad Sci U S A. 1963 Jul;50(1):68-75 PMID: 16578541
  9. Inhibition of Q replicase by excess template.
    Eur J Biochem. 1972 Jan 21;24(3):530-7 PMID: 5058598
  10. Terminal sequences of bacteriophage RNAs.
    Nature. 1968 Nov 9;220(5167):548-52 PMID: 5686725
  11. Polyethylene sulfonate as inhibitor of initiation by Q replicase.
    Biochim Biophys Acta. 1972 Jan 18;259(1):41-9 PMID: 4551896
  12. Replication of RNA viruses, IV. Initiation of RNA synthesis by the q-beta RNA polymerase.
    Proc Natl Acad Sci U S A. 1967 Apr;57(4):986-93 PMID: 5231359
  13. Comparison of two serologically distinct ribonucleic acid bacteriophages. II. Properties of the nucleic acids and coat proteins.
    J Bacteriol. 1966 Sep;92(3):739-45 PMID: 5922545
  14. Replication of RNA viruses. 8. Direction of chain growth in the Q-beta RNA polymerase reaction.
    J Mol Biol. 1969 Mar 28;40(3):445-55 PMID: 5364716
  15. Replication of RNA viruses. V. Template activity of synthetic ribopolymers in the Q-beta RNA polymerase reaction.
    Proc Natl Acad Sci U S A. 1967 Jun;57(6):1790-7 PMID: 5231413
  16. Specific interaction of tobacco mosaic virus RNA with Q beta-replicase.
    Virology. 1971 Jan;43(1):69-74 PMID: 5543289
  17. Histone or bacterial basic protein required for replication of bacteriophage RNA.
    Nat New Biol. 1972 May 24;237(73):105-8 PMID: 4555812
  18. Resolution of two factors required in the Q-beta-RNA polymerase reaction.
    Nature. 1968 Nov 2;220(5166):478-80 PMID: 4879600
  19. Recognition of size and sequence by an RNA replicase.
    Proc Natl Acad Sci U S A. 1965 Oct;54(4):1189-93 PMID: 5327257
  20. Characterization of the subunits of Q-beta replicase.
    Nature. 1970 Nov 7;228(5271):527-33 PMID: 5472468
  21. Replication of viral RNA, XVI. Enzymatic synthesis of infectious virual RNA with noninfectious Q-beta minus strands as template.
    Proc Natl Acad Sci U S A. 1968 Jan;59(1):145-52 PMID: 5242118
  22. Amber mutant of bacteriophage Q capable of causing overproduction of Q replicase.
    J Virol. 1973 Apr;11(4):603-5 PMID: 4573365
  23. An extracellular Darwinian experiment with a self-duplicating nucleic acid molecule.
    Proc Natl Acad Sci U S A. 1967 Jul;58(1):217-24 PMID: 5231602
  24. Multiple genetic components in bromegrass mosaic virus.
    Nat New Biol. 1971 Jul 14;232(28):40-3 PMID: 5284451
  25. Specific template requirments of RNA replicases.
    Proc Natl Acad Sci U S A. 1965 Aug;54(2):579-87 PMID: 5217445
  26. Phage-specific and host proteins in the replication of bacteriophage RNA.
    Fed Proc. 1970 May-Jun;29(3):1170-5 PMID: 4315363
  27. A new method for the purification of Q RNA-dependent RNA polymerase.
    Biochim Biophys Acta. 1972 Feb 23;262(1):88-100 PMID: 4552904
Article Info
Journal
Proceedings of the National Academy of Sciences of the United States of America
Abbr.
Proc Natl Acad Sci U S A
ISSN
0027-8424
Published
1974-04-00
Pages
1371-5
Language
English
Region
United States
NLM ID
7505876
PMCID
PMC388230
Subset
IM
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]