Pigmentoarchitectonic pathology of the isocortex in juvenile neuronal ceroid-lipofuscinosis: axonal enlargements in layer IIIab and cell loss in layer V.

Acta neuropathologica ·Vol. 46 ·No. 1-2 ·1979-04-12 ·Pages 79-83

Braak H, Goebel HH

Abstract

Pigment preparations of 800 micrometer thickness and Golgi studies of the isocortex in juvenile neuronal ceroid-lipofuscinosis, morphologically proven by electron microscopy, revealed: 1. giant axonal dilatations of IIIab-pyramids. These expansions exceeded by far those found in pyramidal cell axons of other isocortical layers. 2. severe numerical reduction of neurons in the ganglionic layer.

MeSH Terms

Adolescent Axons/ultrastructure Cerebral Cortex/pathology,ultrastructure Ceroid Humans Lipidoses/pathology Lipofuscin Male Neurons/ultrastructure

Chemicals

Ceroid Lipofuscin

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Braak H

Goebel H H

References (32)

32 references, click to expand

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Article Info

Journal

Acta neuropathologica

Abbr.

Acta Neuropathol

ISSN

0001-6322

DOI

10.1007/BF00684808

Published

1979-04-12

Pages

79-83

Language

English

Region

Germany

NLM ID

0412041

Subset

External Links

PubMed source DOI: 10.1007/BF00684808 View journal details

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Pigmentoarchitectonic pathology of the isocortex in juvenile neuronal ceroid-lipofuscinosis: axonal enlargements in layer IIIab and cell loss in layer V.

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