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PMID: 4538029 Published · ppublish English Journal Article

Effects of intraventriculary injected 6-OH dopamine or midbrain raphe lesion on morphine analgesia in rats.

Psychopharmacologia ·Vol. 25 ·No. 2 ·1972-00-00 ·Pages 175-82

Samanin R, Bernasconi S

Abstract

暂无摘要

MeSH Terms
5-Hydroxytryptophan/pharmacology Analgesia Animals Brain Chemistry Catecholamines/analysis Dopamine/analysis,pharmacology Drug Antagonism Drug Synergism Female Morphine/antagonists & inhibitors Norepinephrine/analysis Rats Serotonin/analysis
Chemicals
Catecholamines Serotonin Morphine 5-Hydroxytryptophan Dopamine Norepinephrine
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Samanin R
Bernasconi S
References (22)
22 references, click to expand
  1. Studies on central nervous system depressants. (III). Influence of some tranquillizing agents on morphine analgesia.
    Arch Int Pharmacodyn Ther. 1963 Jan 1;141:223-32 PMID: 14024875
  2. THE ACTION OF RESERPINE AND ALPHA-METHYL-M-TYROSINE ON THE ANALGESIC EFFECT OF MORPHINE IN RATS AND MICE.
    J Pharm Pharmacol. 1964 Mar;16:198-206 PMID: 14163982
  3. A SENSITIVE METHOD FOR SPECTROPHOTOFLUOROMETRIC ASSAY OF CATECHOLAMINES.
    Int J Neuropharmacol. 1964 Dec;3:643-9 PMID: 14347090
  4. Effects of alpha-methyl-p-tyrosine, p-chlorophenylalanine, l-beta-(3,4-dihydroxyphenyl)alanine, 5-hydroxytryptophan and diethyldithiocarbamate on the analgesic activity of morphine and methylamphetamine in the mouse.
    Br J Pharmacol. 1971 Aug;42(4):512-21 PMID: 4256024
  5. The effect of reserpine and alpha-methyldopa on the analgesic action of morphine in the mouse.
    J Pharm Pharmacol. 1967 Nov;19(11):709-13 PMID: 4383691
  6. Modification of morphine analgesia by drugs affecting adrenergic and tryptaminergic mechanisms.
    J Pharm Pharmacol. 1970 Dec;22(12):930-5 PMID: 4395516
  7. Morphine and codeine. The analgesic effect in tolerant and non-tolerant rats.
    Acta Pharmacol Toxicol (Copenh). 1967;25:Suppl 3:3-83 PMID: 4861760
  8. The fluorometric assay of catecholamines and related compounds: improvements and extensions to the hydroxyindole technique.
    Anal Biochem. 1968 Feb;22(2):269-79 PMID: 4868086
  9. Increase of morphine-induced analgesia by stimulation of the nucleus raphe dorsalis.
    Eur J Pharmacol. 1971 Nov-Dec;16(3):298-302 PMID: 5132555
  10. A spectrofluorometric method for the simultaneous determination of 2-(5-hydroxyindol-3-yl) ethylamine (serotonin) and 5-hydroxyindol-3-yl-acetic acid in the brain.
    Pharmacology. 1969;2(3):171-5 PMID: 5346142
  11. Lesions of central norepinephrine terminals with 6-OH-dopamine: biochemistry and fine structure.
    Science. 1969 Dec 5;166(3910):1284-6 PMID: 5350323
  12. Effect of 5-hydroxytryptamine on morphine analgesia in rabbits.
    Ann Med Exp Biol Fenn. 1969;47(2):113-23 PMID: 5360652
  13. Effects of 6-hydroxydopamine on CNS catecholamines, spontaneous motor activity and amphetamine induced hyperactivity in rats.
    Nature. 1970 Mar 7;225(5236):961-2 PMID: 5415137
  14. Reduced effect of morphine in midbrain raphe lesioned rats.
    Eur J Pharmacol. 1970;10(3):339-43 PMID: 5422460
  15. Effects of 6-hydroxydopamine on catecholamine containing neurones in the rat brain.
    J Neurochem. 1970 Feb;17(2):269-78 PMID: 5494056
  16. Increased serotonin turnover in the acutely morphine treated rat.
    Life Sci I. 1971 Sep 1;10(17):977-83 PMID: 5570138
  17. Antagonism of the analgesic effect of morphine and other drugs by p-chlorophenylalanine, a serotonin depletor.
    Psychopharmacologia. 1968;12(4):278-85 PMID: 5652213
  18. Effect of reserpine and alpha-methyl-tyrosine on morphine analgesia.
    Int J Neuropharmacol. 1968 May;7(3):283-92 PMID: 5720518
  19. Studies on behavioural and biochemical changes in rats after lesion of midbrain raphé.
    Eur J Pharmacol. 1968 Nov;4(4):371-6 PMID: 5724914
  20. Morphine tolerance, physical dependence, and synthesis of brain 5-hydroxytryptamine.
    Science. 1968 Dec 13;162(3859):1290-2 PMID: 5748987
  21. Modification of morphine analgesia in the rat by biogenic amines administered intraventricularly.
    Br J Pharmacol. 1969 Feb;35(2):P362-3 PMID: 5774060
  22. A simple and rapid method for injecting H3-norepinephrine into the lateral ventricle of the rat brain.
    Life Sci. 1967 Feb 1;6(3):281-91 PMID: 6071872
Article Info
Journal
Psychopharmacologia
Abbr.
Psychopharmacologia
DOI
10.1007/BF00423195
Published
1972-00-00
Pages
175-82
Language
English
Region
Germany
NLM ID
7609417
Subset
IM
External Links
PubMed source DOI: 10.1007/BF00423195
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