Home LiteratureArticle Details
PMID: 4597710 Published · ppublish English Journal Article

Chloramphenicol acetyltransferases specified by fi minus R factors.

Antimicrobial agents and chemotherapy ·Vol. 3 ·No. 1 ·1973-01-00 ·Pages 99-104

Foster TJ, Shaw WV

Abstract

Chloramphenicol acetyltransferases specified by fi(-) (F fertility-noninhibiting) R factors were compared with those specified by the fi(+) R factors R1, 222, and R6-S. Three classes of enzyme were distinguished: class I was determined by group N fi(-) R factors and was indistinguishable from the enzyme determined by fi(+) R factors, class II was correlated with group W fi(-) R factors, and class III was determined by R387, an unclassified fi(-) R factor.

MeSH Terms
Acetyltransferases/metabolism Chloramphenicol Drug Resistance, Microbial Escherichia coli/enzymology Extrachromosomal Inheritance Microbial Sensitivity Tests
Chemicals
Chloramphenicol Acetyltransferases
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Foster T J
Shaw W V
References (21)
21 references, click to expand
  1. Episome-mediated transfer of drug resistance in Enterobacteriaceae. V. Spontaneous segregation and recombination of resistance factors in Salmonella typhimurium.
    J Bacteriol. 1962 Sep;84:422-30 PMID: 13999114
  2. EPISOME-MEDIATED TRANSFER OF DRUG RESISTANCE IN ENTEROBACTERIACEAE. VII. TWO TYPES OF NATURALLY OCCURRING R FACTORS.
    J Bacteriol. 1964 Sep;88:716-26 PMID: 14208512
  3. EPISOME-MEDIATED TRANSFER OF DRUG RESISTANCE IN ENTEROBACTERIACEAE. 8. SIX-DRUG-RESISTANCE R FACTOR.
    J Bacteriol. 1964 Oct;88:922-8 PMID: 14219055
  4. The relation of resistance transfer factors to the F-factor (sex-factor) of Escherichia coli K12.
    Genet Res. 1966 Feb;7(1):134-40 PMID: 5324663
  5. The enzymatic acetylation of chloramphenicol by extracts of R factor-resistant Escherichia coli.
    J Biol Chem. 1967 Feb 25;242(4):687-93 PMID: 5335032
  6. Enzymatic chlorampheicol acetylation and R factor induced antibiotic resistance in Enterobacteriaceae.
    Antimicrob Agents Chemother (Bethesda). 1966;6:221-6 PMID: 5985248
  7. The enzymatic acetylation of chloramphenicol by the multiple drug-resistant Escherichia coli carrying R factor.
    J Biol Chem. 1967 Oct 25;242(20):4722-30 PMID: 4964809
  8. Characterization of chloramphenicol acetyltransferase from chloramphenicol-resistant Staphylococcus aureus.
    J Bacteriol. 1968 Jan;95(1):28-36 PMID: 4965980
  9. Chloramphenicol resistance by enzymatic acetylation: comparative aspects.
    Antimicrob Agents Chemother (Bethesda). 1967;7:257-63 PMID: 4876090
  10. Transduction of various R factors by phage P1 in Escherichia coli and by phage P22 in Salmonella typhimurium.
    J Bacteriol. 1968 Nov;96(5):1791-5 PMID: 4882025
  11. A comparative study of eight distinct beta-lactamases synthesized by gram-negative bacteria.
    J Gen Microbiol. 1970 Apr;61(1):43-61 PMID: 5489064
  12. Detection of resistance factors in fish pathogen Aeromonas liquefaciens.
    J Gen Microbiol. 1971 Mar;65(3):343-9 PMID: 4933803
  13. The problems of drug-resistant pathogenic bacteria. Comparative enzymology of chloramphenicol resistance.
    Ann N Y Acad Sci. 1971 Jun 11;182:234-42 PMID: 5285289
  14. Compatibility groups among fi - R factors.
    Nature. 1971 Nov 26;234(5326):222-3 PMID: 5002028
  15. Properties of an R factor from Pseudomonas aeruginosa.
    J Bacteriol. 1971 Dec;108(3):1244-9 PMID: 4945193
  16. New type of R factors incapable of inactivating chloramphenicol.
    J Bacteriol. 1972 Jan;109(1):1-7 PMID: 4550661
  17. Recombination and complementation between R factors in Escheichia coli K 12.
    Genet Res. 1971 Dec;18(3):287-97 PMID: 4945740
  18. R124, an fi R factor of a new compatibility class.
    J Gen Microbiol. 1972 Jul;71(2):403-5 PMID: 4558791
  19. Hybridization of variants of chloramphenicol acetyltransferase specified by fi + and fi - R factors.
    Proc Natl Acad Sci U S A. 1972 Oct;69(10):3049-53 PMID: 4628098
  20. Chloramphenicol acetyl transferase formed by wild-type and complementing R factors in Escherichia coli K12.
    J Gen Microbiol. 1972 Aug;71(3):575-80 PMID: 4567226
  21. Episome-mediated transfer of drug resistance in Enterobacteriaceae. I. Transfer of resistance factors by conjugation.
    J Bacteriol. 1961 May;81:669-78 PMID: 13783344
Article Info
Journal
Antimicrobial agents and chemotherapy
Abbr.
Antimicrob Agents Chemother
ISSN
0066-4804
DOI
10.1128/AAC.3.1.99
Published
1973-01-00
Pages
99-104
Language
English
Region
United States
NLM ID
0315061
PMCID
PMC444367
Subset
IM
External Links
PubMed source DOI: 10.1128/AAC.3.1.99 PMC Full Text View journal details
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2