Home LiteratureArticle Details
PMID: 4613733 Published · ppublish English Journal Article

Immunological studies in a case of T-cell leukaemia.

Journal of clinical pathology ·Vol. 27 ·No. 11 ·1974-11-00 ·Pages 851-9

Stathopoulos G, Papamichail M, Sheldon P, Catovsky D, Davies AJ, Holborow EJ, Wiltshaw E

Abstract

The blood lymphocytes from a case of prolymphocytic leukaemia were subjected to a battery of different tests in order to establish as certainly as possible their T or B cell type of origin. The results of the tests for surface markers indicated the T-cell origin of the leukaemic cells in this patient, and this provided a good opportunity to determine the participation of T cells in the various tests proposed for measuring human lymphocyte function.

MeSH Terms
Aminosalicylic Acids/immunology Animals Antibodies/analysis Autoradiography Complement System Proteins/immunology Concanavalin A Electrophoresis Erythrocytes/immunology Female Fluorescent Antibody Technique Humans Immune Adherence Reaction Immune Sera Immunoglobulins/analysis Immunologic Techniques Lectins Leukemia, Lymphoid/immunology Lymphocytes/ultrastructure Microscopy, Electron Middle Aged Mitogens/immunology Sheep/immunology T-Lymphocytes/immunology,metabolism Thymidine/metabolism Tritium
Chemicals
Aminosalicylic Acids Antibodies Immune Sera Immunoglobulins Lectins Mitogens Tritium Concanavalin A Complement System Proteins Thymidine
Authors & Affiliations
7 authors, click to expand affiliations / ORCID
Stathopoulos G
Papamichail M
Sheldon P
Catovsky D
Davies A J
Holborow E J
Wiltshaw E
References (24)
24 references, click to expand
  1. The mitogenic effects of endotoxin and staphylococcal enterotoxin B on mouse spleen cells and human peripheral lymphocytes.
    J Immunol. 1970 Dec;105(6):1453-8 PMID: 4921787
  2. A population of lymphocytes bearing a membrane receptor for antigen-antibody-complement complexes. I. Separation and characterization.
    J Exp Med. 1970 Oct 1;132(4):702-20 PMID: 4101362
  3. Binding of sheep red blood cells to a large population of human lymphocytes.
    Nature. 1971 Apr 23;230(5295):531-2 PMID: 4927757
  4. Immunoglobulins on the surface of lymphocytes. IV. Distribution in hypogammaglobulinemia, cellular immune deficiency, and chronic lymphatic leukemia.
    J Clin Invest. 1971 Nov;50(11):2368-75 PMID: 4999540
  5. Immunoglobulins on the surface of human lymphocytes.
    Lancet. 1971 Oct 16;2(7729):850-2 PMID: 4106875
  6. Surface-bound immunoglobulin as a marker of B lymphocytes in man.
    Nat New Biol. 1971 Dec 22;234(51):251-2 PMID: 4942988
  7. Subpopulations of human peripheral blood lymphocytes distinguished by combined rosette formation and membrane immunofluorescence.
    Lancet. 1972 Jul 8;2(7767):64-6 PMID: 4113306
  8. Interaction of aggregated -globulin with B lymphocytes.
    J Exp Med. 1972 Jul 1;136(1):191-6 PMID: 4113510
  9. Surface markers on human T and B lymphocytes. I. A large population of lymphocytes forming nonimmune rosettes with sheep red blood cells.
    J Exp Med. 1972 Aug 1;136(2):207-15 PMID: 4114496
  10. Surface bound immunoglobulins as a cell marker in human lymphoproliferative diseases.
    Blood. 1972 Dec;40(6):777-94 PMID: 4628444
  11. PPD tuberculin--a B-cell mitogen.
    Nat New Biol. 1972 Dec 13;240(102):198-200 PMID: 4539345
  12. Characterisation of malignant mediastinal lymphoid neoplasm (Sternberg sarcoma) as thymic in origin.
    Lancet. 1973 Jan 13;1(7794):74-7 PMID: 4118652
  13. An antigenic marker for human thymic lymphocytes.
    J Immunol. 1973 Mar;110(3):884-7 PMID: 4540134
  14. Periodate-induced lymphocyte transformation. II. Character of response and comparison with phytohemagglutinin and pokeweed mitogen stimulation.
    Exp Cell Res. 1973 Apr;78(2):279-86 PMID: 4349013
  15. Thymic origin of atypical lymphoid cells in infectious mononucleosis.
    Lancet. 1973 May 26;1(7813):1153-5 PMID: 4123541
  16. Lymphocyte binding of aggregated IgG and surface Ig staining in chronic lymphocytic leukaemia.
    Clin Exp Immunol. 1973 May;14(1):97-106 PMID: 4577289
  17. Membrane antigens specific for human lymphoid cells in the dividing phase.
    J Exp Med. 1973 Jul 1;138(1):64-70 PMID: 4577622
  18. Indications of the thymus-derived nature of the proliferating cells in six patients with Sézary's syndrome.
    N Engl J Med. 1973 Aug 16;289(7):341-4 PMID: 4268776
  19. Prolymphocytic leukaemia of B and T cell type.
    Lancet. 1973 Aug 4;2(7823):232-4 PMID: 4124423
  20. Thymus-derived proliferating lymphocytes in chronic lymphocytic leukaemia.
    Lancet. 1973 Aug 4;2(7823):263-4 PMID: 4124455
  21. Elicitation of selective T and B lymphocyte responses by cell surface binding ligands.
    Transplant Rev. 1972;11:87-130 PMID: 4588912
  22. Antibodies specific for human T lymphocytes in cold agglutinin and lymphocytotoxic sera.
    Eur J Immunol. 1973 Dec;3(12):824-8 PMID: 4205559
  23. Activation of human T and B lymphocytes by polyclonal mitogens.
    Nature. 1974 Apr 19;248(5450):698-701 PMID: 4545414
  24. Sezary syndrome--a malignant reticulemic erythroderma.
    JAMA. 1961 Aug 19;177:465-72 PMID: 13775424
Article Info
Journal
Journal of clinical pathology
Abbr.
J Clin Pathol
ISSN
0021-9746
DOI
10.1136/jcp.27.11.851
Published
1974-11-00
Pages
851-9
Language
English
Region
England
NLM ID
0376601
PMCID
PMC475512
Subset
IM
External Links
PubMed source DOI: 10.1136/jcp.27.11.851 PMC Full Text View journal details
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2