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PMID: 5031265 Published · ppublish English Journal Article

Electrophoretic characterization of circulating human proinsulin and insulin.

Diabetologia ·Vol. 8 ·No. 2 ·1972-04-00 ·Pages 136-40

Gutman RA, Lazarus NR, Recant L

Abstract

暂无摘要

MeSH Terms
Acrylamides Body Weight Chromatography, Gel Electrophoresis Glucose/pharmacology Humans Insulin/analysis,blood Obesity/blood Proinsulin/analysis,blood Protein Conformation Tolbutamide/pharmacology
Chemicals
Acrylamides Insulin Proinsulin Tolbutamide Glucose
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Gutman R A
Lazarus N R
Recant L
References (11)
11 references, click to expand
  1. Significance of human plasma insulin Sephadex fractions.
    Diabetes. 1969 Dec;18(12):834-9 PMID: 4311900
  2. Human serum proinsulin.
    J Clin Invest. 1970 Mar;49(3):497-507 PMID: 5461203
  3. Studies on human proinsulin. Isolation and amino acid sequence of the human pancreatic C-peptide.
    J Biol Chem. 1971 Mar 10;246(5):1375-86 PMID: 5101771
  4. Identification of proinsulin and C-peptide in human serum by a specific immunoassay.
    Proc Natl Acad Sci U S A. 1970 Sep;67(1):148-55 PMID: 4318774
  5. The isolation of insulin from a single cat pancreas.
    Biochim Biophys Acta. 1962 Sep 10;63:150-3 PMID: 14025543
  6. Isolation and properties of proinsulin, intermediate forms, and other minor components from crystalline bovine insulin.
    Diabetes. 1968 Dec;17(12):725-36 PMID: 5726253
  7. A method for electrophoretic characterization on polyacrylamide gel of circulating insulin immunoreactive substances.
    Anal Biochem. 1971 Apr;40(2):241-6 PMID: 5102549
  8. Circulating proinsulin-like material in patients with functioning insulinomas.
    N Engl J Med. 1971 May 6;284(18):1003-8 PMID: 4324225
  9. Isolation and characterization of proinsulin C-peptide from bovine pancreas.
    J Biol Chem. 1971 Mar 10;246(5):1365-74 PMID: 5545080
  10. [Bovine proinsulin: isolation, properties and activation by trypsin].
    Hoppe Seylers Z Physiol Chem. 1968 Sep;349(9):1157-68 PMID: 5706142
  11. "Big insulin": a new component of plasma insulin detected by immunoassay.
    Proc Natl Acad Sci U S A. 1968 Sep;61(1):138-45 PMID: 4301586
Article Info
Journal
Diabetologia
Abbr.
Diabetologia
ISSN
0012-186X
DOI
10.1007/BF01235639
Published
1972-04-00
Pages
136-40
Language
English
Region
Germany
NLM ID
0006777
Subset
IM
External Links
PubMed source DOI: 10.1007/BF01235639 View journal details
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