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PMID: 5284246 Published · ppublish ger Journal Article

Thymidylat-synthetase in white blood cells and bone marrow under normal and pathological conditions.

Die Thymidylat-Synthetase in weissen Blutzellen und im Knochenmark unter normalen und pathologischen Bedingungen.

Klinische Wochenschrift ·Vol. 49 ·No. 13 ·1971-07-01 ·Pages 755-62

Wilmanns W, Neef V

Abstract

暂无摘要

MeSH Terms
Anemia, Pernicious/enzymology Bone Marrow/enzymology Bone Marrow Cells Humans L-Lactate Dehydrogenase/blood Leukemia/enzymology Leukemia, Erythroblastic, Acute/enzymology Leukemia, Lymphoid/enzymology Leukemia, Myeloid/enzymology,therapy Leukocytes/enzymology Methyltransferases/blood Middle Aged Primary Myelofibrosis/enzymology Radiation Effects Spleen/radiation effects Tetrahydrofolate Dehydrogenase/blood Thymidine Kinase/blood Transferases/blood Uracil Nucleotides
Chemicals
Uracil Nucleotides L-Lactate Dehydrogenase Tetrahydrofolate Dehydrogenase Transferases Methyltransferases Thymidine Kinase
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Wilmanns W
Neef V
References (18)
18 references, click to expand
  1. Direct spectrophotometric evidence for the oxidation of tetrahydrofolate during the enzymatic synthesis of thymidylate.
    J Biol Chem. 1961 Mar;236:PC11-2 PMID: 13782537
  2. [Thymidine kinase in normal and leukemic myeloid cells].
    Klin Wochenschr. 1967 May 15;45(10):505-11 PMID: 5239336
  3. Proliferative activity of blast cells in leukemia and myelofibrosis. Morphological differences between proliferating and non-proliferating blast cells.
    Acta Med Scand. 1965 Sep;178(3):263-80 PMID: 5213256
  4. [Thymine nucleotide synthesis and proliferation of bone marrow cells in megaloblastic anemias under the effect of vitamin B 12].
    Klin Wochenschr. 1967 Feb 15;45(4):176-88 PMID: 5586138
  5. Structural requirements of the tetrahydropteridine cofactor for the serine aldolase and the thymidylate synthetase reactions.
    Biochem Biophys Res Commun. 1960 Dec;3:603-7 PMID: 13708237
  6. Leukemic cell proliferation as determined by in vitro deoxyribonucleic acid synthesis.
    J Clin Invest. 1962 Feb;41:360-9 PMID: 13881943
  7. STUDIES ON NORMAL AND LEUKEMIC LEUKOCYTES. VI. THYMIDYLATE SYNTHETASE AND DEOXYCYTIDYLATE DEAMINASE.
    J Clin Invest. 1963 Dec;42:1913-21 PMID: 14086778
  8. The biosynthesis of thymidylic acid. III. Purification of thymidylate synthetase and its spectrophotometric assay.
    J Biol Chem. 1962 Mar;237:812-8 PMID: 13869774
  9. Studies on fluorinated pyrimidines. XIII. Inhibition of thymidylate synthetase.
    J Biol Chem. 1961 Nov;236:3006-13 PMID: 13905041
  10. [THE SIGNIFICANCE OF THE FOLIC ACID METABOLISM FOR THE NORMAL AND PATHOLOGICAL MATURATION OF BLOOD CELLS].
    Klin Wochenschr. 1963 Nov 15;41:1077-82 PMID: 14109864
  11. The role of the folate coenzymes in cellular division. A review.
    Cancer Res. 1962 Apr;22:267-81 PMID: 14480820
  12. Virus-induced acquisition of metabolic function. III. Formation and some properties of thymidylate synthetase of bacteriophage-infected Escherichia coli.
    J Biol Chem. 1959 Nov;234:2981-6 PMID: 13823355
  13. [Desoxyribonucleic acid polymerase in the human leukocytes. Enzyme activity in leukemia and virus infections].
    Klin Wochenschr. 1968 Apr 15;46(8):407-13 PMID: 5247007
  14. The metabolic functions of vitamin B12.
    N Engl J Med. 1962 Apr 12;266:765-71 contd PMID: 13866301
  15. COBAMIDES AND RIBONUCLEOTIDE REDUCTION. I. COBAMIDE STIMULATION OF RIBONUCLEOTIDE REDUCTION IN EXTRACTS OF LACTOBACILLUS LEICHMANNII.
    J Biol Chem. 1965 May;240:2173-80 PMID: 14299643
  16. [FOLIC ACID METABOLISM AND ONE-CARBON UNITS].
    Klin Wochenschr. 1963 Nov 1;41:1030-8 PMID: 14098334
  17. [Autoradiographic and enzyme-chemical studies of DNA synthesis in leukemia cells. I. Correlation of thymidine-kinase and 3 H-thymidine labelling index].
    Klin Wochenschr. 1970 Jul 1;48(13):780-8 PMID: 5286417
  18. STUDIES ON UNBALANCED GROWTH IN ESCHERICHIA COLI.
    Proc Natl Acad Sci U S A. 1954 Oct;40(10):885-93 PMID: 16589586
Article Info
Journal
Klinische Wochenschrift
Abbr.
Klin Wochenschr
ISSN
0023-2173
DOI
10.1007/BF01495498
Published
1971-07-01
Pages
755-62
Language
ger
Region
Germany
NLM ID
2985205R
Subset
IM
External Links
PubMed source DOI: 10.1007/BF01495498
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