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PMID: 564911 Published · ppublish English Journal Article

Cytoplasmic filaments and gap junctions in epithelial cells and myofibroblasts during wound healing.

The Journal of cell biology ·Vol. 76 ·No. 3 ·1978-03-00 ·Pages 561-8

Gabbiani G, Chaponnier C, Hüttner I

Abstract

During the healing of an experimental skin wound, epidermal cells and granulation tissue fibroblasts (myofibroblasts) develop an extensive cytoplasmic contactile apparatus. Concurrently, the proportion of epidermal cell surface occupied by gap junctions increases when compared to normal skin, and newly formed gap junctions appear between myofibroblasts; this suggests that epidermal cell migration and granulation tissue contraction are synchronized phenomena.

MeSH Terms
Animals Cell Movement Cytoplasm/ultrastructure Cytoskeleton/ultrastructure Desmosomes/ultrastructure Epithelium/ultrastructure Fibroblasts/ultrastructure Intercellular Junctions/ultrastructure Rabbits Rats Skin/injuries,ultrastructure Wound Healing
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Gabbiani G
Chaponnier C
Hüttner I
References (25)
25 references, click to expand
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Article Info
Journal
The Journal of cell biology
Abbr.
J Cell Biol
ISSN
0021-9525
DOI
10.1083/jcb.76.3.561
Published
1978-03-00
Pages
561-8
Language
English
Region
United States
NLM ID
0375356
PMCID
PMC2110008
Subset
IM
External Links
PubMed source DOI: 10.1083/jcb.76.3.561 PMC Full Text View journal details
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