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PMID: 6094485 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

Two-component suppression of recF143 by recA441 in Escherichia coli K-12.

Journal of bacteriology ·Vol. 160 ·No. 2 ·1984-11-00 ·Pages 702-5

Volkert MR, Margossian LJ, Clark AJ

Abstract

Sensitivity to UV irradiation conferred by recF143 was partially suppressed by recA441 (also known as tif-1). A temperature-conditional component depended on uvrA function and is thought to involve thermal induction of excision repair enzymes. In a uvrA6 mutant, a temperature-independent component of suppression was seen. This is thought to indicate that recA441 also caused temperature-independent changes in recA activity. Two hypotheses are offered to explain how recA441 produced both thermosensitive and thermoindependent effects.

MeSH Terms
Bacterial Proteins/genetics,radiation effects Dose-Response Relationship, Radiation Escherichia coli/genetics,radiation effects Genes Genes, Bacterial Genotype Rec A Recombinases/genetics Suppression, Genetic Ultraviolet Rays
Chemicals
Bacterial Proteins Rec A Recombinases
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Volkert M R
Margossian L J
Clark A J
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29 references, click to expand
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Article Info
Journal
Journal of bacteriology
Abbr.
J Bacteriol
ISSN
0021-9193
Published
1984-11-00
Pages
702-5
Language
English
Region
United States
NLM ID
2985120R
PMCID
PMC214793
Subset
IM
Grants
NIAID NIH HHS · AI05371 · United States
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