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PMID: 6117475 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Effect of glucocorticoids on the appearance of gamma-glutamyl transpeptidase activity in primary cultures of adult rat hepatocytes.

Experientia ·Vol. 37 ·No. 9 ·1981-00-00 ·Pages 941-3

Coloma J, Gómez-Lechón MJ, García MD, Felíu JE, Báguena J

Abstract

Primary cultures of adult rat liver parenchymal cells showed a progressive rise of gamma-glutamyl transpeptidase (GGT) activity (E.C. 2.3.2.2) after the first 5 days of culture. The presence of dexamethasone and other synthetic glucocorticoids in the culture medium partially prevented this increase.

MeSH Terms
Animals Cells, Cultured Dexamethasone/pharmacology Glucocorticoids/pharmacology Kinetics Liver/cytology,enzymology Male Rats Rats, Inbred Strains Triamcinolone/pharmacology gamma-Glutamyltransferase/antagonists & inhibitors,metabolism
Chemicals
Glucocorticoids Triamcinolone Dexamethasone gamma-Glutamyltransferase
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Coloma J
Gómez-Lechón M J
García M D
Felíu J E
Báguena J
References (19)
19 references, click to expand
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Article Info
Journal
Experientia
Abbr.
Experientia
ISSN
0014-4754
DOI
10.1007/BF01971766
Published
1981-00-00
Pages
941-3
Language
English
Region
Switzerland
NLM ID
0376547
Subset
IM
External Links
PubMed source DOI: 10.1007/BF01971766
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