Antigenic relationship between serotype-specific agglutinogen and fimbriae of Bordetella pertussis.

Infection and immunity ·Vol. 37 ·No. 3 ·1982-09-00 ·Pages 1278-81

Ashworth LA, Irons LI, Dowsett AB

Abstract

The widely held view that the filamentous hemagglutinin (FHA) of Bordetella pertussis is derived from fimbriae (pili) is not supported by studies of fimbriation and FHA content of the organism. Fimbriae do not label specifically with antibody to FHA in immuno-electron microscopy but do label with antibody to serotype-specific agglutinogen.

MeSH Terms

Agglutinins/immunology Antigens, Bacterial/immunology Bordetella pertussis/classification,immunology,ultrastructure Fimbriae, Bacterial/immunology Hemagglutinins/immunology Microscopy, Electron Serotyping

Chemicals

Agglutinins Antigens, Bacterial Hemagglutinins

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Ashworth L A

Irons L I

Dowsett A B

References (7)

7 references, click to expand

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Purified K-agglutinogen of Bordetella pertussis and its properties.
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Leukocytosis-promoting factor of Bordetella pertussis. 3. Its identity with protective antigen.
Infect Immun. 1974 May;9(5):801-10 PMID: 4363229
Isolation and properties of the leukocytosis- and lymphocytosis-promoting factor of Bordetella pertussis.
J Exp Med. 1976 Jun 1;143(6):1483-502 PMID: 58054
Separation and characterization of two distinct hemagglutinins contained in purified leukocytosis-promoting factor from Bordetella pertussis.
Biochim Biophys Acta. 1976 Oct 22;444(3):765-82 PMID: 186106
Fimbrial hemagglutinin in stationary and shake cultures of Bordetella pertussis.
Infect Immun. 1979 Aug;25(2):764-7 PMID: 39897
Rabbit nasopharyngeal colonization by Bordetella pertussis: the effects of immunization on clearance and on serum and nasal antibody levels.
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Article Info

Journal

Infection and immunity

Abbr.

Infect Immun

ISSN

0019-9567

DOI

10.1128/iai.37.3.1278-1281.1982

Published

1982-09-00

Pages

1278-81

Language

English

Region

United States

NLM ID

0246127

PMCID

PMC347675

Subset

External Links

PubMed source DOI: 10.1128/iai.37.3.1278-1281.1982 PMC Full Text View journal details

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Antigenic relationship between serotype-specific agglutinogen and fimbriae of Bordetella pertussis.

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