Home LiteratureArticle Details
PMID: 6148752 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Pilus genes of Neisseria gonorrheae: chromosomal organization and DNA sequence.

Meyer TF, Billyard E, Haas R, Storzbach S, So M

Abstract

We have mapped two regions of the Neisseria gonorrheae genome, pilE1 and pilE2, which are involved in pilus expression. When the cells are in the piliated P+ state, these two loci carry sequences necessary for pilin production. A silent locus, pilS1, also maps near pilE1 and pilE2. pilS1 contains structural gene information but lacks pilus promoter sequences. The pilus gene sequences in pilE1 and pilE2 are identical in strain MS11.

MeSH Terms
Amino Acid Sequence Bacterial Outer Membrane Proteins/genetics Base Sequence Chromosome Mapping Chromosomes, Bacterial/physiology DNA Restriction Enzymes DNA, Bacterial/genetics Fimbriae Proteins Fimbriae, Bacterial/physiology Genes Genes, Bacterial Neisseria gonorrhoeae/genetics
Chemicals
Bacterial Outer Membrane Proteins DNA, Bacterial Fimbriae Proteins DNA Restriction Enzymes
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Meyer T F
Billyard E
Haas R
Storzbach S
So M
References (25)
25 references, click to expand
  1. Neisseria gonorrhoeae. II. Colonial variation and pathogenicity during 35 months in vitro.
    J Bacteriol. 1968 Sep;96(3):596-605 PMID: 4979098
  2. Neisseria gonorrhoeae 3. Demonstration of presumed appendages to cells from different colony types.
    Acta Pathol Microbiol Scand B Microbiol Immunol. 1971;79(3):437-9 PMID: 4997136
  3. Studies on gonococcus infection. IV. Pili: their role in attachment of gonococci to tissue culture cells.
    J Exp Med. 1973 Mar 1;137(3):571-89 PMID: 4631989
  4. A catenated DNA molecule as an intermediate in the replication of the resistance transfer factor R6K in Escherichia coli.
    Biochem Biophys Res Commun. 1973 Oct 15;54(4):1451-9 PMID: 4585292
  5. Differential attachment by piliated and nonpiliated Neisseria gonorrhoeae to human sperm.
    Infect Immun. 1974 May;9(5):897-902 PMID: 4207517
  6. The human fallopian tube: a laboratory model for gonococcal infection.
    J Infect Dis. 1974 Jun;129(6):650-9 PMID: 4209721
  7. Pili as a mediator of the attachment of gonococci to human erythrocytes.
    Infect Immun. 1976 May;13(5):1483-9 PMID: 818026
  8. The preparation and properties of gonococcal pili.
    J Gen Microbiol. 1977 Sep;102(1):169-77 PMID: 410905
  9. Neisseria pili proteins: amino-terminal amino acid sequences and identification of an unusual amino acid.
    Biochemistry. 1978 Feb 7;17(3):442-5 PMID: 413571
  10. Studies on gonococcus infection. XII. Colony color and opacity varienats of gonococci.
    Infect Immun. 1978 Jan;19(1):320-31 PMID: 415006
  11. Games parasites play: how parasites evade immune surveillance.
    Nature. 1979 May 3;279(5708):21-6 PMID: 88015
  12. Biological properties of two distinct pilus types produced by isogenic variants of Neisseria gonorrhoeae P9.
    J Bacteriol. 1980 Jan;141(1):393-6 PMID: 6101593
  13. Sequencing end-labeled DNA with base-specific chemical cleavages.
    Methods Enzymol. 1980;65(1):499-560 PMID: 6246368
  14. Comparative virulence of opacity variants of Neisseria gonorrhoeae strain P9.
    Infect Immun. 1981 Mar;31(3):965-70 PMID: 6785243
  15. Colony opacity and protein II compositions of gonococci.
    Infect Immun. 1982 Jul;37(1):359-68 PMID: 6809633
  16. Pilus expression in Neisseria gonorrhoeae involves chromosomal rearrangement.
    Cell. 1982 Aug;30(1):45-52 PMID: 6127165
  17. Biochemical comparison of pili from variants of Neisseria gonorrhoeae P9.
    J Gen Microbiol. 1982 Sep;128(9):2105-11 PMID: 6129285
  18. A pilus peptide vaccine for the prevention of gonorrhea.
    Prog Allergy. 1983;33:314-31 PMID: 6187017
  19. Cellular differentiation, cell lineages, and transposable genetic cassettes in yeast.
    Curr Top Dev Biol. 1983;18:1-14 PMID: 6301757
  20. Immunoglobulin gene rearrangement and expression during lymphocyte development.
    Curr Top Dev Biol. 1983;18:15-58 PMID: 6404604
  21. Studies on transformation of Escherichia coli with plasmids.
    J Mol Biol. 1983 Jun 5;166(4):557-80 PMID: 6345791
  22. Mechanisms of protein localization.
    Microbiol Rev. 1983 Sep;47(3):313-44 PMID: 6355805
  23. Gonococcal pili. Primary structure and receptor binding domain.
    J Exp Med. 1984 May 1;159(5):1351-70 PMID: 6143785
  24. Opacity determinants of Neisseria gonorrhoeae: gene expression and chromosomal linkage to the gonococcal pilus gene.
    Cell. 1984 Jun;37(2):447-56 PMID: 6144397
  25. NEISSERIA GONORRHOEAE. I. VIRULENCE GENETICALLY LINKED TO CLONAL VARIATION.
    J Bacteriol. 1963 Jun;85:1274-9 PMID: 14047217
Article Info
Journal
Proceedings of the National Academy of Sciences of the United States of America
Abbr.
Proc Natl Acad Sci U S A
ISSN
0027-8424
Published
1984-10-00
Pages
6110-4
Language
English
Region
United States
NLM ID
7505876
PMCID
PMC391869
Subset
IM
Grants
NIAID NIH HHS · AI 20845 · United States
Databases
GENBANK
K02078, K02079, K02080
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]