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PMID: 6171517 Published · ppublish English Comparative Study Journal Article Research Support, Non-U.S. Gov't

Immunological nonidentity of heat-labile enterotoxins from human and porcine enterotoxigenic Escherichia coli.

Infection and immunity ·Vol. 34 ·No. 2 ·1981-11-00 ·Pages 337-40

Honda T, Tsuji T, Takeda Y, Miwatani T

Abstract

The Ouchterlony double-gel diffusion test demonstrated that heat-labile enterotoxin (LT) from human strains of enterotoxigenic Escherichia coli was antigenically related but not identical to that from porcine E. coli. All human strains examined produced immunologically identical LTs, and all porcine strains examined produced immunologically identical LTs. The Biken test (modified Elek test), developed for detection of E. coli LT (Honda et al., J. Clin. Microbiol. 13: 1-5, 1981), was useful for confirmation of these results.

MeSH Terms
Animals Antigens, Bacterial/analysis Bacterial Toxins Cross Reactions Enterotoxins/immunology Epitopes/analysis Escherichia coli/immunology,isolation & purification Escherichia coli Proteins Humans Immunodiffusion Swine/microbiology
Chemicals
Antigens, Bacterial Bacterial Toxins Enterotoxins Epitopes Escherichia coli Proteins heat-labile enterotoxin, E coli
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Honda T
Tsuji T
Takeda Y
Miwatani T
References (12)
12 references, click to expand
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Article Info
Journal
Infection and immunity
Abbr.
Infect Immun
ISSN
0019-9567
Published
1981-11-00
Pages
337-40
Language
English
Region
United States
NLM ID
0246127
PMCID
PMC350870
Subset
IM
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