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PMID: 6188109 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Mitochondrial circular RNAs are absent in sporulating cells of Saccharomyces cerevisiae.

Nucleic acids research ·Vol. 11 ·No. 6 ·1983-03-25 ·Pages 1735-46

Schroeder R, Breitenbach M, Schweyen RJ

Abstract

During sporulation of Saccharomyces cerevisiae the mitochondria undergo a differentiation process, leading to a "spore mitochondrion", which differs both physiologically and morphologically from vegetative cell mitochondria. We report here the behaviour of the mitochondrial transcripts during this differentiation process. The circular transcripts representing spliced introns of the two mitochondrial split genes for cytochrome b and for the subunit 1 of the cytochrome c oxidase, which are very abundant during vegetative growth, are not detectable in sporulating cells. This loss does neither take place in haploid cells under sporulation conditions nor when erythromycin is added to the medium. The process of some mRNAs is advanced in relation to their precursors in sporulating cells.

MeSH Terms
Base Sequence DNA, Mitochondrial/genetics,isolation & purification Electron Transport Complex IV/genetics Kinetics Mitochondria/physiology Oxygen Consumption RNA/genetics RNA, Circular Saccharomyces cerevisiae/genetics,physiology Spores, Fungal/physiology Transcription, Genetic
Chemicals
DNA, Mitochondrial RNA, Circular RNA Electron Transport Complex IV
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Schroeder R
Breitenbach M
Schweyen R J
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20 references, click to expand
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Article Info
Journal
Nucleic acids research
Abbr.
Nucleic Acids Res
ISSN
0305-1048
DOI
10.1093/nar/11.6.1735
Published
1983-03-25
Pages
1735-46
Language
English
Region
England
NLM ID
0411011
PMCID
PMC325832
Subset
IM
External Links
PubMed source DOI: 10.1093/nar/11.6.1735 PMC Full Text View journal details
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