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PMID: 6278419 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

The genome of Plasmodium falciparum. I: DNA base composition.

Nucleic acids research ·Vol. 10 ·No. 2 ·1982-01-22 ·Pages 539-46

Pollack Y, Katzen AL, Spira DT, Golenser J

Abstract

Some structural properties of the DNA of Plasmodium falciparum were studied thoroughly using several techniques. Its G+C content was found to be extremely low (17-19%), the lowest reported for a living organism. The DNA seems to be composed only of the four major bases as no methylated bases were detected. This DNA had a Tm value of 62.5 degrees C and its denaturation profile showed no marked intramolecular heterogeneity.

MeSH Terms
Animals Base Composition Chromatography, High Pressure Liquid DNA/genetics DNA Restriction Enzymes Nucleic Acid Conformation Nucleic Acid Denaturation Plasmodium falciparum/genetics
Chemicals
DNA DNA Restriction Enzymes
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Pollack Y
Katzen A L
Spira D T
Golenser J
References (14)
14 references, click to expand
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Article Info
Journal
Nucleic acids research
Abbr.
Nucleic Acids Res
ISSN
0305-1048
DOI
10.1093/nar/10.2.539
Published
1982-01-22
Pages
539-46
Language
English
Region
England
NLM ID
0411011
PMCID
PMC326156
Subset
IM
External Links
PubMed source DOI: 10.1093/nar/10.2.539 PMC Full Text View journal details
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