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PMID: 6289313 Published · ppublish English Journal Article

Chromosomal mapping of the simian sarcoma virus onc gene analogue in human cells.

Proceedings of the National Academy of Sciences of the United States of America ·Vol. 79 ·No. 15 ·1982-08-00 ·Pages 4691-5

Swan DC, McBride OW, Robbins KC, Keithley DA, Reddy EP, Aaronson SA

Abstract

The primate cell-derived transforming gene (v-sis) of simian sarcoma virus (SSV) is represented as a single copy marker within cellular DNAs of mammalian species including human. The human analogue of v-sis can be distinguished from its rodent counterparts by Southern blotting analysis of EcoRI-restricted DNAs. By testing for the presence of the human v-sis-related fragment, c-sis (human), in somatic cell hybrids possessing varying numbers of human chromosome, as well as in segregants of such hybrids, it was possible to assign c-sis to human chromosome 22.

MeSH Terms
Cell Transformation, Viral Chromosome Mapping Chromosomes, Human, 21-22 and Y Genes, Viral Humans Hybrid Cells/ultrastructure Nucleic Acid Hybridization Retroviridae/genetics Sarcoma Virus, Woolly Monkey/genetics
Authors & Affiliations
6 authors, click to expand affiliations / ORCID
Swan D C
McBride O W
Robbins K C
Keithley D A
Reddy E P
Aaronson S A
References (46)
46 references, click to expand
  1. Human-mouse hybrid cell lines containing partial complements of human chromosomes and functioning human genes.
    Proc Natl Acad Sci U S A. 1967 Sep;58(3):1104-11 PMID: 5233838
  2. Loss of T-antigen from somatic hybrids between mouse cells and SV40-transformed human cells.
    Proc Natl Acad Sci U S A. 1968 Apr;59(4):1132-5 PMID: 4297332
  3. C-type virus in tumor tissue of a woolly monkey (Lagothrix spp.) with fibrosarcoma.
    J Natl Cancer Inst. 1971 Oct;47(4):881-9 PMID: 4328953
  4. A rapid banding technique for human chromosomes.
    Lancet. 1971 Oct 30;2(7731):971-2 PMID: 4107917
  5. A review of enzyme polymorphism, linkage and electrophoretic conditions for mouse and somatic cell hybrids in starch gels.
    J Histochem Cytochem. 1973 Dec;21(12):1066-81 PMID: 4587225
  6. Properties and location of poly(A) in Rous sarcoma virus RNA.
    J Virol. 1974 Dec;14(6):1515-29 PMID: 4372409
  7. Mouse alpha-globin genes and alpha-globin-like pseudogenes are not syntenic.
    Proc Natl Acad Sci U S A. 1981 Oct;78(10):6362-6 PMID: 6947235
  8. Developmental hierarchy of immunoglobulin gene rearrangements in human leukemic pre-B-cells.
    Proc Natl Acad Sci U S A. 1981 Nov;78(11):7096-100 PMID: 6273911
  9. Proposal for naming host cell-derived inserts in retrovirus genomes.
    J Virol. 1981 Dec;40(3):953-7 PMID: 7321107
  10. Generation of BALB-MuSV and Ha-MuSC by type C virus transduction of homologous transforming genes from different species.
    Cell. 1981 Oct;26(1 Pt 1):129-34 PMID: 6276008
  11. Cellular genes analogous to retroviral onc genes are transcribed in human tumour cells.
    Nature. 1982 Jan 14;295(5845):116-9 PMID: 6173755
  12. Chromosomal location of human kappa and lambda immunoglobulin light chain constant region genes.
    J Exp Med. 1982 May 1;155(5):1480-90 PMID: 6802926
  13. Primate origin of the cell-derived sequences of simian sarcoma virus.
    J Virol. 1982 Feb;41(2):721-5 PMID: 6281482
  14. Expression of cellular homologues of retroviral onc genes in human hematopoietic cells.
    Proc Natl Acad Sci U S A. 1982 Apr;79(8):2490-4 PMID: 6283530
  15. The use of drug-resistant markers to study the hybridization of mouse fibroblasts.
    Exp Cell Res. 1966 Jan;41(1):190-6 PMID: 4952025
  16. DELETION OF THYMIDINE KINASE ACTIVITY FROM L CELLS RESISTANT TO BROMODEOXYURIDINE.
    Exp Cell Res. 1963 Aug;31:297-312 PMID: 14056989
  17. Molecular cloning of integrated simian sarcoma virus: genome organization of infectious DNA clones.
    Proc Natl Acad Sci U S A. 1981 May;78(5):2918-22 PMID: 6265924
  18. DNA related to the transforming gene(s) of avian sarcoma viruses is present in normal avian DNA.
    Nature. 1976 Mar 11;260(5547):170-3 PMID: 176594
  19. A general method for isolation of high molecular weight DNA from eukaryotes.
    Nucleic Acids Res. 1976 Sep;3(9):2303-8 PMID: 987581
  20. Mechanisms of giemsa banding of chromosomes. I. Giemsa-11 banding with azure and eosin.
    Exp Cell Res. 1976 Oct 1;102(1):85-94 PMID: 61884
  21. Improved techniques for the induction of mammalian cell hybridization by polyethylene glycol.
    Somatic Cell Genet. 1976 Mar;2(2):165-76 PMID: 1028164
  22. Retroviruses.
    Annu Rev Biochem. 1978;47:35-88 PMID: 354499
  23. Avian leukemia viruses: interaction with their target cells in vivo and in vitro.
    Biochim Biophys Acta. 1978 Nov 17;516(3):269-99 PMID: 215208
  24. A defined subgenomic fragment of in vitro synthesized Moloney sarcoma virus DNA can induce cell transformation upon transfection.
    Cell. 1979 Jan;16(1):63-75 PMID: 84715
  25. Philadelphia chromosome in human multiple myeloma.
    J Natl Cancer Inst. 1979 Jul;63(1):11-6 PMID: 286821
  26. Chromosomal assignment of the mouse kappa light chain genes.
    Proc Natl Acad Sci U S A. 1979 Jun;76(6):2735-9 PMID: 111241
  27. Nature and distribution of feline sarcoma virus nucleotide sequences.
    J Virol. 1979 Jun;30(3):821-7 PMID: 225544
  28. Chromosomal location of the genes for human immunoglobulin heavy chains.
    Proc Natl Acad Sci U S A. 1979 Jul;76(7):3416-9 PMID: 114999
  29. The transforming gene of Moloney murine sarcoma virus.
    Nature. 1979 Nov 22;282(5737):378-83 PMID: 503218
  30. Nonrandom chromosome changes involving the Ig gene-carrying chromosomes 12 and 6 in pristane-induced mouse plasmacytomas.
    Cell. 1979 Dec;18(4):1001-7 PMID: 519762
  31. Properties of a normal mouse cell DNA sequence (sarc) homologous to the src sequence of Moloney sarcoma virus.
    Science. 1980 Mar 14;207(4436):1222-4 PMID: 6243788
  32. Oligoribonucleotide map and protein of CMII: detection of conserved and nonconserved genetic elements in avian acute leukemia viruses CMII, MC29, and MH2.
    J Virol. 1979 Oct;32(1):208-19 PMID: 232172
  33. Abelson murine leukemia virus mutants with alterations in the virus-specific P120 molecule.
    J Virol. 1980 Jan;33(1):340-8 PMID: 6245237
  34. Chromosomal location of the structural gene cluster encoding murine immunoglobulin heavy chains.
    J Exp Med. 1980 Jun 1;151(6):1545-50 PMID: 6770027
  35. Mapping of transforming region of the Harvey murine sarcoma virus genome by using insertion-deletion mutants constructed in vitro.
    Proc Natl Acad Sci U S A. 1980 Aug;77(8):4674-8 PMID: 6254037
  36. Molecular cloning of a human histocompatibility antigen cDNA fragment.
    Proc Natl Acad Sci U S A. 1980 Oct;77(10):6081-5 PMID: 6934534
  37. Homology exists among the transforming sequences of avian and feline sarcoma viruses.
    Proc Natl Acad Sci U S A. 1980 Nov;77(11):6536-40 PMID: 6256742
  38. Chromosome abnormalities in human leukemia.
    Annu Rev Genet. 1980;14:17-39 PMID: 7011172
  39. A third class of avian sarcoma viruses, defined by related transformation-specific proteins of Yamaguchi 73 and Esh sarcoma viruses.
    Proc Natl Acad Sci U S A. 1981 Apr;78(4):2611-5 PMID: 6264485
  40. The p21 src genes of Harvey and Kirsten sarcoma viruses originate from divergent members of a family of normal vertebrate genes.
    Nature. 1981 Aug 6;292(5823):506-11 PMID: 6265801
  41. Cytogenetic studies on African Burkitt's lymphoma cell lines: t(8;14), t(2;8) and t(8;22) translocations.
    Cancer Genet Cytogenet. 1981 Jun;3(4):307-15 PMID: 7260888
  42. Molecular cloning and comparative analyses of the genomes of simian sarcoma virus and its associated helper virus.
    Proc Natl Acad Sci U S A. 1981 Jun;78(6):3373-7 PMID: 6267588
  43. A human onc gene homologous to the transforming gene (v-sis) of simian sarcoma virus.
    Nature. 1981 Jul 2;292(5818):31-5 PMID: 6268983
  44. Dispersion of alpha-like globin genes of the mouse to three different chromosomes.
    Nature. 1981 Sep 17-23;293(5829):196-200 PMID: 6168916
  45. Assignment of the genes for human lambda immunoglobulin chains to chromosome 22.
    Nature. 1981 Nov 12;294(5837):173-5 PMID: 6795508
  46. The role of gene dosage and genetic transpositions in carcinogenesis.
    Nature. 1981 Nov 26;294(5839):313-8 PMID: 7312030
Article Info
Journal
Proceedings of the National Academy of Sciences of the United States of America
Abbr.
Proc Natl Acad Sci U S A
ISSN
0027-8424
DOI
10.1073/pnas.79.15.4691
Published
1982-08-00
Pages
4691-5
Language
English
Region
United States
NLM ID
7505876
PMCID
PMC346742
Subset
IM
External Links
PubMed source DOI: 10.1073/pnas.79.15.4691 PMC Full Text View journal details
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