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PMID: 6324106 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

The L1Md long interspersed repeat family in the mouse: almost all examples are truncated at one end.

Nucleic acids research ·Vol. 11 ·No. 24 ·1983-12-20 ·Pages 8847-59

Voliva CF, Jahn CL, Comer MB, Hutchison CA, Edgell MH

Abstract

We have characterized a large repetitive element which has been found at seven different locations within the beta globin locus of the BALB/c mouse. This repeat has an unusual structure in that each of the different members has the same end of the element conserved while the other end terminates at a different point in each repeat member. The sequences within the repeats from the beta globin locus have homology with other repetitive families such as the MIF-1, Bam-5, R, and the BamH1 families. These were recently proposed (T. Fanning, (1983) Nucleic Acids Res. 11, 5073-5091) to be part of a structure with the same organization which we found in the globin locus. Probing plaques from a BALB/c genomic library with sequences derived from the repeats in the globin locus shows that virtually all of the repeats from this family are organized in a manner consistent with the proposed structure.

MeSH Terms
Animals Cloning, Molecular DNA Restriction Enzymes Embryo, Mammalian Genes Globins/genetics Mice Mice, Inbred BALB C Nucleic Acid Hybridization Repetitive Sequences, Nucleic Acid
Chemicals
Globins DNA Restriction Enzymes
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Voliva C F
Jahn C L
Comer M B
Hutchison C A
Edgell M H
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24 references, click to expand
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Article Info
Journal
Nucleic acids research
Abbr.
Nucleic Acids Res
ISSN
0305-1048
DOI
10.1093/nar/11.24.8847
Published
1983-12-20
Pages
8847-59
Language
English
Region
England
NLM ID
0411011
PMCID
PMC326629
Subset
IM
Grants
NIAID NIH HHS · AI08998 · United States
NIGMS NIH HHS · GM07092 · United States
NIGMS NIH HHS · GM21313 · United States
Databases
GENBANK
X00233
External Links
PubMed source DOI: 10.1093/nar/11.24.8847 PMC Full Text View journal details
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